Zanaflex (Tizanidine)

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Zanaflex Brand
Dosage Quantity & Price
Tizanidine (Generic alternate to Zanaflex) Generic
Dosage Quantity & Price
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Zanaflex is a medication used to treat muscle spasms caused by certain conditions such as multiple sclerosis and spinal cord injuries. Zanaflex is a short-acting muscle relaxant that blocks nerve impulses (pain sensations) that are sent to the brain. It is a centrally acting α2-adrenergic agonist that works by binding to α2-adrenergic receptor sites in the brain and spinal cord, which leads to decreased activity of motor neurons, decreased muscle tone, and muscle relaxation.

Zanaflex can be taken with or without food and has been proven to be effective in reducing symptoms like stiffness and pain as well as improving mobility. Because of its effectiveness, it is prescribed by doctors around the world for people suffering from muscle spasms.

Uses and Dosage

To take Tizanidine, which comes as a tablet, orally, follow the instructions on your prescription label carefully, taking it exactly as directed. Typically, it is taken either always with or always without food two or three times daily, and your doctor will gradually increase your dose based on your response to the medication.

Do not stop taking Tizanidine without consulting your doctor. Suddenly stopping the medication may result in an increased heart rate or blood pressure, as well as muscle tightness. Your doctor will likely decrease your dose gradually to minimize withdrawal symptoms.

The typical dosing for tizanidine (Zanaflex) in adults over the age of 18 is to start with 2 mg taken orally up to three times a day. The dose can be gradually increased, if necessary, but should not exceed a total of 36 mg per day. Tizanidine is not approved for use in children under the age of 18.

Side Effect

Common Side Effects of Zanaflex (Tizanidine):

  • Back pain
  • Constipation
  • Depression
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Heartburn
  • Increased muscle spasms
  • Nervousness
  • Rash
  • Stomach pain
  • Sweating
  • Tingling sensation in the arms, legs, hands, and feet
  • Vomiting
  • Weakness

Serious Side Effects of Zanaflex (Tizanidine):

  • Changes in vision
  • Extreme tiredness
  • Lack of energy
  • Loss of appetite
  • Nausea
  • Pain in the upper right part of the stomach
  • Seeing things or hearing voices that do not exist
  • Slow heartbeat
  • Unexplained flu-like symptoms
  • Unusual bleeding or bruising
  • Yellowing of the skin or eyes

Form and Strength

Zanaflex (Tizanidine) is available in the following forms and strength:

Zanaflex: Tablet

  • 2 mg

Tizanidine: Tablet

  • 2 mg
  • 4 mg


  • Zanaflex can cause dizziness or drowsiness that may impair your ability to operate heavy machinery or drive a vehicle.
  • Tizanidine may cause low blood pressure in some patients.
  • Zanaflex may interact with other medications, such as certain antibiotics, antifungal medications, and blood pressure medications.
  • Tizanidine should be used with caution in patients with liver disease, as it may increase the risk of liver damage.
  • Zanaflex should not be used by pregnant women unless the potential benefits outweigh the potential risks to the fetus.
  • Zanaflex should not be used in patients with a known hypersensitivity to tizanidine or any of its components.
  • Tizanidine may cause dry mouth, which can increase the risk of tooth decay or gum disease.
  • Zanaflex may cause stomach upset or gastrointestinal side effects, such as nausea or vomiting.
  • Tizanidine may impair cognitive or physical abilities, so it should be used with caution in patients who require mental or physical sharpness, such as pilots or heavy machinery operators.
  • Zanaflex may cause withdrawal symptoms if it is stopped suddenly after long-term use.

Frequently Asked Questions (FAQ)

Is Zanaflex addictive?

Zanaflex can be addictive in some cases. Take the medication exactly as prescribed by your healthcare provider.

Can Zanaflex interact with other medications?

Zanaflex may interact with other medications, inform your healthcare provider about all the medications you are taking.

Can Zanaflex cause drowsiness?

Yes, Zanaflex may cause drowsiness or dizziness, so caution should be taken when operating heavy machinery or driving.

How should I take Zanaflex?

Zanaflex should be taken exactly as prescribed by your healthcare provider. It is typically taken by mouth with or without food, and doses should be spaced evenly throughout the day.


It's important to purchase Zanaflex from verified Canadian pharmacy.

Additional information

Generic name:





2mg, 4mg

Quantities Available:

60, 90, 100