Indications
Uloric (active ingredient: febuxostat) is a prescription medication indicated for:
- Hyperuricemia in Gout: Uloric is used to lower blood uric acid levels in patients with hyperuricemia associated with gout.
Uloric belongs to a class of drugs known as xanthine oxidase inhibitors, which work by reducing the production of uric acid in the body. By lowering uric acid levels, Uloric helps to prevent gout attacks and associated symptoms such as joint pain, swelling, and inflammation.
Uses and Dosage
Uloric (febuxostat) is available in tablet form and is usually taken once daily with or without food. The dosage and duration of treatment may vary depending on the patient's medical condition and response to the treatment. Talk to your doctor before starting Uloric, and follow their instructions carefully to ensure safe and effective use of the medication.
The recommended starting dosage of Uloric is 40 mg once daily. If a patient does not achieve a serum uric acid (sUA) level of less than 6 mg/dL after two weeks, the recommended ULORIC dosage is increased to 80 mg once daily.
Side Effect
Common Side Effects of Uloric (Febuxostat):
- Gout flares
- Joint pain
- Liver problems
- Mild rash
- Nausea
Serious Side Effects of Uloric (Febuxostat):
- Chest pain or pressure
- Dark urine
- Fast heartbeats
- Fever
- Flu-like symptoms
- Lightheadedness
- Muscle aches
- Pain spreading to your jaw or shoulder
- Problems with vision or balance
- Severe weakness
- Shortness of breath
- Skin rash
- Slurred speech
- Sudden numbness or weakness
- Sudden severe headache
- Swollen glands
- Unusual bruising
- Unusual tiredness
- Upper right-side stomach pain
- Yellowing of your skin or eyes
Form and Strength
Uloric (Febuxostat) is available in the following forms and strength:
Uloric: Tablet
- 40 mg
- 80 mg
Febuxostat: Tablet
- 40 mg
- 80 mg
- 120 mg
Caution
- Uloric may increase the risk of heart-related problems, including heart attacks, strokes, and unstable angina.
- It may cause liver problems, including liver failure, jaundice, and elevated liver enzymes.
- Uloric may cause allergic reactions, including rash, hives, and swelling of the face, lips, tongue, and throat.
- Febuxostat may interact with other medications, including drugs that affect liver function or that increase the risk of bleeding.
- Febuxostat may cause kidney problems in some patients, especially those with pre-existing kidney disease.
- Uloric may cause gout flares in some patients, especially during the first few months of treatment.
- Some studies have suggested that Uloric may increase the risk of cancer, although the evidence is not conclusive.
- The safety of Uloric during pregnancy and breastfeeding is not known, and do not use in these populations unless the potential benefits outweigh the risks.
- Uloric may be less effective in elderly patients, and the dosage may need to be adjusted based on age and kidney function.
Frequently Asked Questions (FAQ)
How long does it take for Uloric to start working?
Uloric may take several weeks to start working, and it may take up to 6 months to see the full benefits of the medication.
Can I drink alcohol while taking Uloric?
It is generally safe to drink alcohol in moderation while taking Uloric, but it is important to talk to your doctor about any potential interactions or risks.
Is Uloric safe for use during pregnancy or breastfeeding?
The safety of Uloric during pregnancy or breastfeeding has not been established, and it is important to talk to your doctor if you are pregnant or breastfeeding before taking Uloric.
Is Uloric safe for use in elderly patients?
Uloric may be used in elderly patients, but the dosage may need to be adjusted based on age and kidney function. It is important to talk to your doctor about any special considerations for elderly patients.
How should I store Uloric?
Uloric should be stored at room temperature (between 68°F and 77°F) in a dry place, away from light and heat sources.
Resources
- https://www.hopkinsarthritis.org/patient-corner/drug-information/febuxostat-uloric/
- https://www.webmd.com/drugs/2/drug-151872/uloric-oral/details
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021856s013lbl.pdf
- https://www.rxlist.com/uloric-drug.htm
- https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=ae1e0d8a-03fc-419b-9d44-afa68fbd5681
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