Perphenazine is an oral tablet that should be taken two to four times a day at around the same time each day. Follow the instructions on your prescription label carefully and ask your doctor or pharmacist if you have any questions or do not understand any part of it. Do not take more or less of it or take it more often than prescribed by your doctor.
The recommended dosage of perphenazine varies depending on the condition being treated, individual patient factors, and other medications being taken. The typical starting dose can range from 4mg to 8mg, taken orally three times a day for schizophrenia. The maximum recommended dose is 24mg in a day, but a dose reduction to the minimum effective dose as soon as possible is desirable. The optimal clinical effect or benefit may be achieved at dosages of 24mg occasionally. Elderly patients may require a lower dosage to start.
Continue taking perphenazine even if you feel well. Do not stop taking perphenazine without talking to your doctor. If you suddenly stop taking perphenazine, you may experience withdrawal symptoms such as nausea, vomiting, stomach pain, dizziness, and shakiness. Your doctor will decrease your dose gradually and may prescribe other medication(s) for you to take for several weeks after you stop taking perphenazine to avoid withdrawal symptoms.
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