Seroquel (Quetiapine) is available in the form of tablets and should be taken orally as prescribed by your doctor, typically 2 or 3 times per day with or without food. Seroquel (Quetiapine) tablets should be swallowed whole, as chewing, crushing, or breaking the tablet can reduce its effectiveness. It is important to follow your doctor’s instructions for taking this medication for the best results.
The dosage of Seroquel (quetiapine) is based on the individual patient’s medical condition and response to treatment. Depending on the condition being treated, the dosage of Seroquel may be adjusted based on other medications you are taking. Your doctor will monitor your progress closely and adjust your dosage as needed.
Indication
Initial Dose and Titration
Recommended Dose
Maximum Dose
Schizophrenia – Adults
300 mg/day Dose increases can be made at intervals as short as 1 day and in increments of up to 300 mg/day
400-800 mg/day
800 mg/day
Schizophrenia – Adolescents (13 to 17 years)
Day 1: 50 mg/day
Day 2: 100 mg/day
Day 3: 200 mg/day
Day 4: 300 mg/day
Day 5: 400 mg/day
400-800 mg/day
800 mg/day
Schizophrenia Maintenance -Monotherapy – Adults
Not applicable
400-800 mg/day
800 mg/day
Bipolar I Disorder manic or mixed – Acute monotherapy or adjunct to lithium or divalproex – Adults
Day 1: 300 mg/day
Day 2: 600 mg/day
Day 3: between 400 and 800 mg/day
400-800 mg/day
800 mg/day
Bipolar I Disorder, manic – Acute monotherapy – Children and Adolescents (10 to 17 years)
Day 1: 50 mg/day
Day 2: 100 mg/day
Day 3: 200 mg/day
Day 4: 300 mg/day
Day 5: 400 mg/day
400-600 mg/day
600 mg/day
Bipolar Disorder, Depressive Episodes -Adults
Day 1: 50 mg/day
Day 2: 100 mg/day
Day 3: 200 mg/day
Day 4: 300 mg/day
300 mg/day
300 mg/day
Bipolar I Disorder Maintenance – Adjunct to lithium or divalproex – Adults
Not applicable
400-800 mg/day
800 mg/day
Major Depressive Disorder – Adjunctive Therapy with Antidepressants – Adults
Day 1: 50 mg/day
Day 2: 50 mg/day
Day 3: 150 mg/day
150-300 mg/day
300 mg/day
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