Indications
Salofalk is a prescription medication used to treat inflammatory bowel disease, specifically ulcerative colitis. It contains the active substance mesalazine, which is an anti-inflammatory agent. It works by reducing inflammation in the large intestine (colon) and rectum (back passage). However, it does not cure the disease.
Use and Dosage
To properly use Salofalk Enema, it must be inserted through the rectum as it should not be consumed orally. Administer the Salofalk 4g/60ml Enema preferably at bedtime.
Before using the enema, first empty the bowels, wash your hands, and shake the bottle for 30 seconds. After removing the protective cap from the applicator, place the bottle with the upper end in your hand and lie on your left side. Extend your left leg and bend your right leg to facilitate the action of the enema. Insert the applicator, which is coated with lubricant for easier insertion, into the rectum and point the bottle towards your navel. Gently and tightly squeeze the bottle while maintaining this position. Once the bottle is empty, remove the applicator from the rectum.
Continue with this position for at least 30 minutes to ensure the enema spreads throughout the lower part of the large intestine. Finally, wash your hands again and avoid emptying your bowels again for the rest of the night. Remember that Salofalk Enema should only be used rectally.
Side Effects
Common Side Effects of Salofalk Enema (Mesalazine):
- Upset stomach
- Abdominal pain
- Diarrhea
Serious Side Effects of Salofalk Enema (Mesalazine):
- Severe allergic reactions such as: rash, hives, difficulty breathing, and swelling of the face, lips, tongue, or throat
- Severe stomach pain
- Cramping
- Bloody diarrhea
- Pancreatitis, kidney problems, or liver problems
Forms and Strength
Salofalk Enema (Mesalazine) is available in the following forms and strength:
Salofalk Enema: Enema Kit
- 2g/60mL
- 4g/60mL
Cautions
- Hypersensitivity or allergic reactions: Salofalk Enema contains potassium metabisulphite, which can cause severe allergic reactions in some individuals. Seek medical attention immediately if you experience symptoms such as difficulty breathing, swelling, or rash.
- Renal impairment: Salofalk Enema should be used with caution in patients with renal impairment, as the medication is excreted by the kidneys. Dose adjustments may be necessary in these patients.
- Hepatic impairment: Salofalk Enema should also be used with caution in patients with hepatic impairment, as the medication is metabolized in the liver. Dose adjustments may be necessary in these patients.
- Blood disorders: Salofalk Enema may cause blood disorders such as leukopenia and thrombocytopenia. Patients with a history of blood disorders should use the medication with caution.
- Interaction with other medications: Salofalk Enema may interact with other medications, such as azathioprine and mercaptopurine, which can increase the risk of blood disorders. Inform your healthcare provider of all medications you are taking before using Salofalk Enema.
- Gastrointestinal disorders: Salofalk Enema may worsen gastrointestinal disorders such as stomach ulcers and Crohn's disease. Patients with these conditions should use the medication with caution.
- Electrolyte imbalance: Salofalk Enema may cause electrolyte imbalance, particularly in patients with severe diarrhea or dehydration. Blood tests should be performed regularly to monitor electrolyte levels.
- Pregnancy and breastfeeding: Salofalk Enema is considered safe to use during pregnancy and breastfeeding but consult a healthcare professional before using the medication.
- Children: Salofalk Enema can be used in children, but it should be used with caution and under the supervision of a healthcare professional.
- Infection risk: Salofalk Enema may increase the risk of infection. Patients using the medication should take precautions to avoid infection, such as washing their hands regularly and avoiding contact with individuals who are sick.
Frequently Asked Questions (FAQ)
How long does it take for Salofalk Enema to work for ulcerative colitis?
The effects of Salofalk Enema can vary depending on the severity of the ulcerative colitis and the individual. It can take up to 4-6 weeks to see the full effects of the medication.
Can Salofalk Enema be used for Crohn's disease?
Salofalk Enema is specifically indicated for the treatment of mild-to-moderate ulcerative colitis, not Crohn's disease. However, Mesalazine can be used in other formulations, such as tablets, for the treatment of Crohn's disease.
Can I use Salofalk Enema if I have kidney problems?
Salofalk Enema should be used with caution in patients with renal impairment, as the medication is excreted by the kidneys. Dose adjustments may be necessary in these patients. Consult a healthcare professional before using the medication if you have kidney problems.
Can Salofalk Enema cause hair loss?
Hair loss is not a known side effect of Salofalk Enema. However, consult a healthcare professional if you experience any unexpected side effects.
Resources
- https://www.nps.org.au/assets/medicines/1eafdc17-7b78-4a61-9704-a53300fed7d3.pdf
- https://www.hpra.ie/img/uploaded/swedocuments/2176634.PPA0465_266_001.66530ebb-58ef-43f5-a70c-e853ec03ee71.000001Salofalk%20PIL.160510.pdf
- https://www.mims.com/malaysia/drug/info/salofalk?type=full
- https://www.drfalk.co.uk/salofalk-rectal-preparations/
- https://galenica.gr/en/product/salofalk-enema/
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