Nolvadex D (Tamoxifen)

Indications

Nolvadex D is a medication that contains tamoxifen citrate and is used for various purposes, primarily in the treatment and prevention of breast cancer. It is used to treat hormone receptor-positive breast cancer. It can also be used to help prevent breast cancer in people at high risk for the disease.

Tamoxifen is an antiestrogen drug that blocks estrogen activity in the breast. This helps to stop the growth of breast tumors that rely on estrogen to multiply. It works by blocking the effects of the hormone estrogen in the body. Each tablet contains tamoxifen citrate equivalent to 20 mg of tamoxifen.

Use and Dosage

Nolvadex D comes in the form of Tablet to take by mouth with or without food as directed by your doctor, usually once or twice daily for 5 years. Take Nolvadex D by mouth with or without food, as directed by your doctor. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.

The recommended dose of tamoxifen is usually 20 mg to 40 mg daily. It may be taken as a single dose or divided into two doses. Your doctor will determine the appropriate dosage for your specific condition.

Take the medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Side Effects

Common Side Effects of Nolvadex D (Tamoxifen):

• Bone pain
• Changes in menstrual period
• Constipation
• Diarrhea
• Genital itching
• Hair loss (partial) or hair thinning
• Headache
• Hot flashes
• Leg cramps
• Lightheadedness
• Mild nausea and vomiting
• Muscle pain
• Skin rash
• Swelling of the feet, ankles, or lower leg
• Taste alterations
• Tiredness and weakness

Serious Side Effects of Nolvadex D (Tamoxifen):

• Abdominal pain, bloating, or swelling
• Blurred vision or vision changes
• Cough and shortness of breath
• Increased pain or growth of tumor
• Numbness or tingling of the skin
• Pain or feeling of pressure in the pelvis
• Severe nausea or vomiting

Forms and Strength

Nolvadex D (Tamoxifen) is available in the following forms and strength:

Nolvadex D: Tablet

• 20 mg

Tamoxifen: Tablet

• 20 mg

Cautions

• Pregnancy Category D: Nolvadex D is classified as Pregnancy Category D, which means it may cause harm to an unborn baby if taken during pregnancy. Inform your healthcare provider if you are pregnant or planning to become pregnant.
• Blood Clotting: Tamoxifen has been associated with an increased risk of blood clots. If you have a history of blood clots or are at an increased risk for blood clotting disorders, discuss this with your healthcare provider before taking Nolvadex D.
• Endometrial Cancer: Tamoxifen has been associated with an increased risk of developing endometrial cancer. Discuss the potential risks and benefits of tamoxifen therapy with your healthcare provider, especially if you have a history of endometrial cancer or other uterine conditions.
• Liver Disease: Nolvadex D may affect liver function. If you have a history of liver disease or liver problems, inform your healthcare provider before starting tamoxifen therapy.
• Other Medications: Tamoxifen may interact with certain medications, including selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine and paroxetine. These interactions can affect the effectiveness of tamoxifen or increase the risk of side effects.

Frequently Asked Questions (FAQ)

Who should use tamoxifen?

Tamoxifen is beneficial for people with hormone receptor-positive breast cancer. It can also be used by individuals who are at high risk of developing breast cancer due to a family history of the disease or mutated breast cancer genes.

Can tamoxifen increase the risk of blood clots?

Yes, tamoxifen may increase the risk of blood clots. Inform your doctor if you have a history of blood clots or if you experience symptoms such as leg swelling, redness, or pain.

How long is tamoxifen typically taken for?

The duration of tamoxifen treatment varies depending on individual circumstances. In some cases, it may be taken for 5 years or longer.

Can tamoxifen cause endometrial cancer?

Tamoxifen may slightly increase the risk of developing endometrial (uterine) cancer. Regular gynecological check-ups are important while taking tamoxifen to monitor for any changes or abnormalities.

Resources

• https://www.medbroadcast.com/drug/getdrug/nolvadex-d
• https://www.drugs.com/sfx/nolvadex-d-side-effects.html
• https://www.mims.com/hongkong/drug/info/nolvadex-d?type=full
• https://www.healthdirect.gov.au/medicines/brand/amt,55911000168107/nolvadex-d
• https://www.webmd.com/drugs/2/drug-4495/nolvadex-oral/details