Indications
Nizoral Cream is a topical antifungal medication used to treat various fungal infections of the skin, such as athlete's foot, jock itch, ringworm, and seborrheic dermatitis. It contains ketoconazole as its active ingredient. It works by preventing the growth and spread of fungus. It quickly penetrates the skin to kill the root cause of the fungal infection and relieves itching symptoms and reduces redness.
Ketoconazole cream interferes with the production of ergosterol, which is an essential component of the fungal cell membrane. By hindering the production of ergosterol, the fungal cell membrane becomes weak and prone to damage, causing the cell to die. It generally takes 2 to 4 weeks of regular use to see improvement in the condition being treated.
Uses and Dosage
Nizoral Cream is applied directly to the affected area of skin and is typically used once or twice per day for several weeks until the infection clears up. Nizoral Cream is only for use on the skin and should not be used in the eyes or mouth.
Using Nizoral Cream, clean and thoroughly dry the affected area of skin. Then, apply enough medication to cover the affected skin and some of the surrounding skin. Use the medication only on the skin and do not apply it in the eyes, nose, mouth, or vagina. If the medication gets in the eyes, rinse thoroughly with water.
The dosage and length of treatment depends on the type of infection being treated. Do not apply the medication more often than prescribed, as it will not clear the condition faster, but it may increase side effects. After applying the medication, wash your hands and do not wrap, cover, or bandage the area unless directed to do so by your doctor.
Use Nizoral Cream regularly at the same time(s) each day to get the most benefit from it. Continue to use the medication until the full prescribed amount is finished, even if symptoms disappear after starting ketoconazole. Stopping the medication too early may allow the fungus to continue to grow, which may result in a relapse of the infection.
If your condition lasts after the full prescribed amount of treatment, or if it gets worse at any time, inform your doctor.
Side Effect
Common Side Effects of Nizoral Cream (Ketoconazole):
- Itching
- Skin irritation
- Stinging
- Rash at application site
Serious Side Effects of Nizoral Cream (Ketoconazole):
- Acne
- Bleeding from sore in the mouth
- Blistering, crusting, irritation, itching, or reddening of the skin
- Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- Cracked, dry, or scaly skin
- Discoloration of the fingernails or toenails
- Dizziness
- Eye dryness, irritation, or swelling
- Red rash with watery, yellow-colored, or pus-filled blisters with or without thick yellow to honey-colored crusts
- Skin dryness, pain, rash, redness, or swelling
- Sore in the mouth or on the gums
- Swelling of the face
Form and Strength
Nizoral Cream (Ketoconazole) is available in the following forms and strength:
Nizoral Cream: Cream
- 2 %
Ketoconazole: Cream
- 2 %
Caution
- Allergic reactions: some people may have allergic reactions to ketoconazole, which may cause symptoms such as itching, rash, swelling, or difficulty breathing. If you experience any of these symptoms, stop using Nizoral Cream and seek medical attention immediately.
- Skin irritation: Nizoral Cream may cause skin irritation, burning, or itching in some people. If you experience any of these symptoms, stop using the cream and consult your doctor.
- Interactions with other medications: Nizoral Cream may interact with other medications you are taking, such as blood thinners or antacids. If you are taking other medications, talk to your doctor before using Nizoral Cream.
- Pregnancy and breastfeeding: Nizoral Cream should only be used during pregnancy or breastfeeding if recommended by a doctor, as safety data is limited.
- Liver problems: Ketoconazole has been known to cause liver problems, including liver damage and liver failure, in some rare cases. If you experience symptoms such as dark urine, yellowing of the eyes or skin, abdominal pain, or loss of appetite while using Nizoral Cream, stop using it and consult your doctor immediately.
- Age limitations: Nizoral Cream is not recommended for use in children under the age of 12, as safety and effectiveness in this age group have not been established.
- Non-fungal infections: Nizoral Cream is not effective for treating infections caused by bacteria or viruses, so it should not be used to treat non-fungal skin infections.
- Avoid contact with eyes and mouth: Nizoral Cream is for external use only, and should not come into contact with the eyes, mouth, or other mucous membranes. If this happens accidentally, rinse the affected area thoroughly with water.
Frequently Asked Questions (FAQ)
Can I use Nizoral Cream during pregnancy or breastfeeding?
Nizoral Cream should only be used during pregnancy or breastfeeding if recommended by a doctor, as safety data is limited.
Does Nizoral Cream interact with other medications?
Nizoral Cream may interact with other medications, such as blood thinners or antacids. If you are taking other medications, talk to your doctor before using Nizoral Cream.
Can Nizoral Cream be used for fungal infections on the scalp?
No, Nizoral Cream is not recommended for treating fungal infections on the scalp. Instead, a ketoconazole shampoo (such as Nizoral shampoo) may be used for this purpose.
How long should I use Nizoral Cream?
You should use Nizoral Cream for as long as your doctor or pharmacist recommends. In most cases, Nizoral Cream is used for several weeks until the infection clears up.
What should I do if I miss a dose of Nizoral Cream?
If you miss a dose of Nizoral Cream, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Resources
- https://www.goodrx.com/ketoconazole/what-is
- https://www.mayoclinic.org/drugs-supplements/ketoconazole-topical-route/side-effects/drg-20067739?p=1
- https://www.webmd.com/drugs/2/drug-11220-1052/nizoral-topical/ketoconazole-cream-topical/details
- https://www.rxlist.com/ketoconazole/generic-drug.htm
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/018533s041lbl.pdf
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