Penlac Nail Lacquer (Ciclopirox)

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Penlac Nail Lacquer Brand
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Ciclopirox (Generic alternate to Penlac Nail Lacquer) Generic
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Penlac nail lacquer is a topical medication used to treat fungal infections of the toenails and fingernails. It contains the active ingredient ciclopirox, which is a synthetic antifungal agent. Ciclopirox acts by chelation of polyvalent cations leading to the inhibition of enzymes that are metal-dependent. These enzymes become responsible for the degradation of peroxides in the fungal cell. This action is thought to stop the growth of fungus.

Penlac nail lacquer may be used as part of a comprehensive treatment plan that can also involve the removal of infected nails and the use of other antifungal medications. When applied to the affected nails, Penlac nail lacquer works by preventing the growth and spread of the fungus, allowing the nails to gradually heal over time.

Uses and Dosage

Penlac Nail Lacquer is meant to be applied only to the nails and the skin around them. Before the start of the treatment, remove any loose nail material using a nail file or clipper. Apply Penlac Nail Lacquer once a day at bedtime, unless otherwise directed by your physician, with the applicator on the affected nail and the adjacent skin, avoiding the use of nail cosmetics.

Use Penlac Nail Lacquer on a regular basis and as prescribed by your doctor. Do not modify your medication dosage or frequency without seeking medical advice as it is based on your overall medical condition and response to the treatment. Moreover, avoid discontinuing the medication abruptly unless your physician advises otherwise.

To use Penlac 8% Topical Solution, follow the instructions provided by your doctor or pharmacist. Here are some general guidelines:

  1. Clean the affected nail(s) with soap and water and dry thoroughly.
  2. Apply a thin layer of the Penlac solution to the affected nail(s) and the surrounding skin using the applicator brush provided. Be careful not to get the solution on any unaffected areas.
  3. Allow the solution to dry completely, which may take up to 30 minutes.
  4. Cover the treated nail(s) with a bandage or gauze, if desired.
  5. Leave the solution on the nail(s) for at least 8 hours, then wash it off with soap and water.
  6. Repeat steps 1-5 once a day, usually for 6-12 months or as directed by your doctor.

Note that Penlac Topical Solution is intended for use on the nails and immediately adjacent skin only. Do not apply it to other areas of the body.

Side Effects

Common Side Effects of Penlac Nail Lacquer (Ciclopirox):

  • Acne
  • Changes of the cuticle and/or nail plate
  • Dry skin
  • Elevated creatine phosphokinase levels (cpk)
  • Hair loss
  • Nail disorders (shape change, irritation, ingrown toenails, and discoloration)
  • Rash
  • Redness around finger/toe nails
  • Severe itching
  • Transient burning sensation of the skin and pain

Serious Side Effects of Penlac Nail Lacquer (Ciclopirox):

  • Blistering
  • Discharge
  • Inflammation

Form and Strength

Penlac Nail Lacquer (Ciclopirox) is available in the following forms and strength:

Penlac Nail Lacquer: Solutions

  • 8%

Ciclopirox: Solutions

  • 8%


  • Some people may be allergic to ciclopirox, the active ingredient in Penlac. If you experience symptoms such as itching, swelling, or redness, stop using the medication and seek medical attention right away.
  • Penlac may interact with other medications, including prescription and over-the-counter drugs as well as herbal supplements. Let your doctor know about all the medications you are taking to avoid potential adverse reactions.
  • While uncommon, some people may experience side effects when using Penlac Nail Lacquer. These may include irritation, itching, redness, and swelling of the treated area. If you experience any side effects, talk to your doctor before continuing to use the medication.
  • Penlac Nail Lacquer is generally not recommended as a first-line treatment for fungal nail infections. In some cases, it may take several months of treatment to see improvement in the condition. If you do not see improvement in your symptoms after a few weeks, talk to your doctor about alternative treatment options.
  • It is unclear whether Penlac Nail Lacquer is safe for use during pregnancy or while breastfeeding. Consult your doctor before using the medication if you are pregnant or breastfeeding.
  • Penlac Nail Lacquer is meant to be applied to the nails only. If it comes into contact with the skin, it may cause irritation or a rash.
  • In some cases, the affected nail may need to be removed to fully eliminate the fungal infection. This can be a painful process and may result in some temporary nail deformity.
  • Fungal nail infections can be difficult to treat and may recur after treatment. It is important to continue following good hygiene practices, such as keeping your nails clean and dry, to minimize the risk of recurrence.

Frequently Asked Questions (FAQ)

How long does it take ciclopirox to work?

It depends on what condition you are prescribed ciclopirox to treat. If you are being treated for certain types of skin infections, you might notice that your skin feels less itchy as early as a week after you start ciclopirox cream or topical suspension.

Can Ciclopirox be used to treat other infections besides fungal infections?

No, Ciclopirox is specifically used to treat fungal infections and should not be used to treat other types of infections.

How should I store Ciclopirox?

Store Ciclopirox at room temperature, away from heat and moisture.

Can Ciclopirox be used by children?

The safe use of Ciclopirox in children has not been established. Consult with your pediatrician before using the medication on a child.

Should I continue using Ciclopirox if my symptoms improve before the end of the treatment course?

Continue using Ciclopirox for the full duration of treatment, as recommended by your doctor, even if your symptoms improve before the end of the treatment course.


It's important to purchase Penlac Nail Lacquer from verified Canadian pharmacy.

Additional information

Generic name:






Quantities Available:

6.6g, 6g, 12g