Indications
Nevanac (nepafenac ophthalmic suspension) is a prescription medication used to treat pain and inflammation in the eyes following cataract surgery. Nevanac belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs) and is administered as an eye drop or ophthalmic suspension. It works by inhibiting the production of certain natural substances called prostaglandins, which are responsible for pain and inflammation.
Nepafenac is a prodrug of amfenac, which means that it is converted into amfenac when it is applied to the eye. Amfenac then inhibits the action of cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins. By reducing the level of prostaglandins, Nevanac can reduce inflammation and alleviate pain in the eye.
Uses and Dosage
Nevanac Ophthalmic Suspension is a one drop in the affected eye three times a day, starting one day before cataract surgery and continuing on the day of surgery and for two weeks after surgery. The suspension should be administered at evenly spaced intervals throughout the day, and it may be used in conjunction with other prescription eye drops if necessary.
Here are the general steps to use Nevanac Ophthalmic Suspension:
- Wash your hands thoroughly with soap and water.
- Tilt your head back and pull down your lower eyelid to create a small pocket.
- Hold the dropper tip pointing downwards and press the bottle gently to release one drop into the pocket created by your lower eyelid.
- Close your eye and press your finger gently against the corner of your eye near your nose for one to two minutes to prevent the medication from draining out of your eye.
- If you need to use Nevanac in the other eye, repeat the steps above.
- Do not allow the dropper tip to touch your eye or any other surface, as this can cause contamination and infection.
- You can replace the cap on the bottle after each use and store it at room temperature.
Use this medication exactly as prescribed by your doctor and report any side effects or concerns to your healthcare provider.
Side Effects
Common Side Effects of Nevanac (Nepafenac):
- Blurred or hazy vision
- Decreased vision
- Feeling like something is in your eye
- Increased pressure inside the eye
- Sticky feeling in the eye
Serious Side Effects of Nevanac (Nepafenac):
- Crusting or drainage of your eyes
- Difficulty breathing
- Eyelid pain
- Hives
- Increased sensitivity to light
- Puffy eyelids
- Severe eye pain or redness
- Swelling of your face, lips, tongue, or throat
- Trouble opening your eyes
- Unusual bleeding or bruising
- Vision problems
- Watery eyes
- Wounds that will not heal
Form and Strength
Nevanac (Nepafenac) is available in the following forms and strength:
Nevanac: Ophthalmic Suspension
- 0.1%
Nepafenac: Ophthalmic Suspension
- 0.1%
Caution
- Some people may be allergic to Nepafenac or other NSAIDs. If you experience signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek medical attention right away.
- Nepafenac may have anticoagulant properties and may increase the risk of bleeding, especially in patients with a history of bleeding disorders. It is recommended to use Nevanac with caution in such patients.
- Cornea problems: Nevanac should not be used in patients with active or suspected corneal infections, or in those who have a compromised corneal surface.
- Nor should Nevanac be used while wearing contact lenses. If you wear contact lenses, wait at least 15 minutes after applying Nevanac before inserting your lenses.
- Nevanac may worsen certain pre-existing eye conditions, such as dry eye or glaucoma. Consult your doctor if you have any concerns.
- The safety and efficacy of Nevanac have not been established in children under the age of 10 years.
- The safety of Nevanac in pregnant and breastfeeding women is unknown. Consult with your healthcare provider before using this medication if you are pregnant or breastfeeding.
- Nevanac can be absorbed systemically and could potentially interact with other medication that you may be taking. Inform your doctor of all medications you are taking, including over-the-counter products.
- Nepafenac may cause temporary blurred vision or other visual disturbances. Do not drive or operate machinery until your vision clears up.
- Do not use Nevanac if you have an eye injury or if you are recovering from eye surgery other than cataract surgery.
- If you miss a dose, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Frequently Asked Questions (FAQ)
Is Nevanac safe for long-term use?
The safety of Nevanac has not been established for long-term use. Contact your doctor if you are concerned about the duration of your treatment with Nevanac.
Can Nevanac interact with other medications?
Yes, there are some medications that may interact with Nevanac. Tell your doctor about all the medications you are taking.
Resources
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021862s008lbl.pdf
- https://www.webmd.com/drugs/2/drug-94080/nevanac-ophthalmic-eye/details
- https://www.goodrx.com/ilevro/what-is
- https://www.empr.com/drug/nevanac/
- https://www.mayoclinic.org/drugs-supplements/nepafenac-ophthalmic-route/side-effects/drg-20067489?p=1
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