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Metro Cream

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Metronidazole

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Metro Cream (metronidazole 0.75%) is a prescription topical medication used to treat inflammatory skin lesions associated with rosacea.

It contains metronidazole, an antimicrobial ingredient that helps reduce skin inflammation and improve rosacea-related breakouts.

Metro Cream belongs to a class of medications called topical nitroimidazole antimicrobials. Although metronidazole has antibacterial properties, its benefits in treating rosacea are believed to come mainly from its anti-inflammatory effects.

Metro Cream is commonly prescribed to treat inflammatory papules and pustules associated with rosacea, a chronic skin condition that primarily affects the face.

Rosacea may cause facial redness, flushing, visible blood vessels, and small, inflamed bumps that resemble acne.

These symptoms commonly appear on the cheeks, nose, chin, and forehead.

By reducing skin inflammation, Metro Cream helps decrease the number of inflammatory bumps and improve the appearance of affected skin.

However, Metro Cream does not cure rosacea. Symptoms may return over time, and some patients may require ongoing treatment to manage their condition.

Treatment of Rosacea

Metro Cream is indicated for the treatment of inflammatory papules and pustules associated with rosacea.

Rosacea is a long-term inflammatory skin condition that commonly affects the central areas of the face.

It may cause persistent redness, frequent flushing, visible blood vessels, and acne-like bumps.

The exact cause of rosacea is not fully understood.

However, several factors may contribute to its development, including an overactive inflammatory response, changes in blood vessels, and increased sensitivity to certain environmental triggers.

Some people with rosacea may also have an increased number of Demodex mites, which naturally live on human skin.

These factors may contribute to irritation and inflammation in susceptible individuals.

Rosacea symptoms can vary from person to person.

Some patients experience mild facial redness, while others develop frequent breakouts, burning sensations, or sensitive skin.

Metro Cream helps manage inflammatory rosacea by reducing the skin inflammation associated with red bumps and pus-filled lesions.

With regular treatment, the affected skin may gradually become smoother and less inflamed.

Metro Cream helps control rosacea symptoms, but it does not permanently eliminate the underlying condition.

Treatment of Inflammatory Papules

Metro Cream is used to reduce inflammatory papules associated with rosacea.

Papules are small, raised bumps that develop when the skin becomes inflamed.

These bumps are usually red or pink, although they may appear darker or more discolored on certain skin tones.

Unlike pustules, papules do not contain visible pus.

They commonly develop on the cheeks, nose, forehead, and chin.

Papules may appear in clusters and can make the skin feel rough or uneven.

Some patients may also experience tenderness, burning, or sensitivity around the affected areas.

Although rosacea papules may resemble ordinary acne, the two conditions have different underlying causes.

Rosacea is associated with chronic inflammation and abnormal skin sensitivity, while acne commonly involves clogged pores, excess oil production, and other factors.

Metro Cream helps reduce the inflammation associated with rosacea papules.

As inflammation decreases, the bumps may gradually become smaller and less noticeable.

The surrounding skin may also become less irritated.

Apply Metro Cream consistently as directed by your healthcare provider to help reduce inflammatory papules and manage rosacea-related breakouts.

Treatment of Inflammatory Pustules

Metro Cream is also indicated for the treatment of inflammatory pustules caused by rosacea.

Pustules are small, raised skin bumps that contain pus.

They often appear as red or inflamed bumps with a white or yellow center.

Pustules may develop when the skin’s inflammatory response affects the hair follicles and surrounding tissues.

They commonly appear on the cheeks, nose, forehead, and chin.

Some patients develop only a few pustules, while others experience repeated breakouts affecting larger areas of the face.

These lesions may cause tenderness, irritation, or discomfort.

Metro Cream helps reduce the inflammatory activity associated with pustule formation.

As treatment continues, existing pustules may gradually improve, and fewer new lesions may develop.

However, improvement is usually gradual rather than immediate.

Avoid squeezing or picking at pustules because this may increase irritation and damage the surrounding skin.

Continue using Metro Cream for the recommended treatment period, even if the number of pustules begins to decrease.

Management of Facial Redness Associated With Rosacea

Rosacea commonly causes redness or discoloration across the cheeks, nose, forehead, and chin.

This redness may develop because of inflammation and changes in the small blood vessels near the skin’s surface.

Some patients experience temporary flushing, while others develop redness that remains visible for longer periods.

Facial redness may become more noticeable after exposure to sunlight, hot temperatures, spicy foods, alcohol, or emotional stress.

Metro Cream may help reduce redness associated with inflammatory rosacea, especially when it occurs alongside papules and pustules.

As skin inflammation improves, the affected areas may appear less red or irritated.

However, Metro Cream is generally more effective for inflammatory bumps than for persistent redness caused by widened blood vessels.

It does not directly remove visible facial blood vessels or reliably prevent flushing episodes.

Patients with persistent redness may require additional treatments recommended by their healthcare provider.

Metro Cream may improve inflammation-related redness, but it may not completely eliminate persistent facial redness or visible blood vessels.

How Does Metro Cream Work?

Metro Cream contains metronidazole, a medication with antimicrobial and anti-inflammatory properties.

The exact way metronidazole improves rosacea is not completely understood.

However, its effectiveness is believed to involve reducing inflammatory activity in the skin.

Rosacea develops partly because the skin’s inflammatory response becomes unusually active.

This inflammation can cause redness, swelling, papules, pustules, and increased skin sensitivity.

Metro Cream helps reduce these inflammatory changes, allowing the skin to gradually improve.

Reduces Skin Inflammation

One of the main benefits of Metro Cream is its ability to reduce inflammation associated with rosacea.

Inflammation is the body’s natural response to irritation, injury, or other triggers.

However, people with rosacea may experience an increased inflammatory response even when there is no harmful infection.

This can cause repeated redness, swelling, and inflammatory breakouts.

Metronidazole appears to interfere with certain inflammatory processes in the skin.

As inflammation decreases, papules and pustules may gradually become less noticeable.

This helps improve the overall appearance of rosacea-affected skin.

May Reduce Oxidative Stress

Oxidative stress occurs when substances called free radicals build up and contribute to cellular damage.

Free radicals are unstable molecules that can affect healthy cells and tissues.

People with rosacea may experience increased oxidative stress in the skin, which can contribute to inflammation.

Research suggests that metronidazole may help limit certain inflammatory reactions involving reactive oxygen species.

These substances are produced during normal immune activity but may contribute to irritation when present in excessive amounts.

By reducing some of this inflammatory activity, Metro Cream may help improve rosacea-related skin lesions.

However, the exact importance of this effect in rosacea treatment remains uncertain.

Has Antimicrobial Properties

Metronidazole also has antimicrobial activity against certain microorganisms.

It works against susceptible anaerobic bacteria and some protozoa.

Anaerobic bacteria are microorganisms that can grow in environments with little or no oxygen.

However, rosacea is not simply a bacterial infection.

The condition involves several factors, including inflammation, skin sensitivity, and changes in blood vessel activity.

For this reason, Metro Cream’s benefits in rosacea are not believed to depend mainly on killing bacteria.

The exact mechanism of Metro Cream in treating rosacea remains unknown, but its anti-inflammatory properties appear to play an important role. 

How Long Does Metro Cream Take to Work?

Metro Cream begins acting on the skin after application, but visible improvements usually develop gradually.

The time needed to see results depends on the severity of rosacea, the number of inflammatory lesions, and your response to treatment.

Some patients may notice reduced redness, fewer papules, or less skin irritation after several weeks of regular use.

More noticeable improvements may develop after approximately three to six weeks.

However, some patients require eight to nine weeks or longer to achieve a more complete response.

Metro Cream is commonly applied twice daily, in the morning and evening, when using the 0.75% formulation.

Your healthcare provider will determine the appropriate treatment schedule based on your symptoms and skin condition.

Rosacea is a chronic condition, so symptoms may improve during treatment and return after the medication is stopped.

Some patients may require continued or maintenance treatment to keep inflammatory breakouts under control.

Do not stop using Metro Cream simply because your skin begins to look better. Follow the treatment duration recommended by your healthcare provider.

If your symptoms do not improve after the expected treatment period, contact your healthcare provider for reassessment.

Can Metro Cream Treat Acne?

Metro Cream is primarily indicated for treating inflammatory lesions associated with rosacea, not ordinary acne vulgaris.

Although rosacea and acne can cause similar-looking bumps, they are different skin conditions.

Acne commonly develops when pores become clogged with oil and dead skin cells.

This can lead to blackheads, whiteheads, papules, pustules, and sometimes deeper cysts.

Rosacea, on the other hand, is a chronic inflammatory condition that commonly causes facial redness, flushing, skin sensitivity, and acne-like bumps.

Unlike ordinary acne, rosacea usually does not cause blackheads or whiteheads.

Metro Cream helps reduce rosacea-related papules and pustules through its anti-inflammatory effects.

However, it is not a standard treatment for ordinary acne.

Using Metro Cream for an undiagnosed skin condition may delay appropriate treatment.

Consult your healthcare provider if you are unsure whether your facial bumps are caused by rosacea, acne, or another skin condition.

Can Metro Cream Help With Sensitive Skin?

People with rosacea often experience increased skin sensitivity.

Their skin may react more easily to sunlight, temperature changes, skin care products, and environmental irritants.

Common symptoms include burning, stinging, dryness, tightness, and irritation.

Metro Cream may help reduce some inflammation-related symptoms as rosacea improves.

The cream formulation may also be suitable for some patients who prefer a moisturizing texture.

However, Metro Cream is not a general-purpose treatment for sensitive skin.

It is specifically prescribed to manage certain inflammatory symptoms of rosacea.

Some patients may experience temporary dryness, burning, stinging, or irritation when applying the medication.

Using harsh cleansers, exfoliating products, or strongly fragranced skin care products may make these reactions worse.

A gentle skin care routine may help support treatment.

If Metro Cream causes persistent burning, worsening redness, or significant irritation, contact your healthcare provider before continuing treatment.

Important Information About Metro Cream

Metro Cream is intended for external use on the skin only.

Avoid applying the medication to your eyes, mouth, inside the nose, or other sensitive areas.

It should not be swallowed or used to treat infections inside the body.

Metro Cream 0.75% is commonly applied twice daily to the affected areas of the face, following gentle cleansing.

Use only the amount recommended by your healthcare provider.

Applying more cream than prescribed will not necessarily improve results and may increase skin irritation.

Possible side effects include dryness, redness, burning, stinging, itching, and mild skin discomfort.

Do not use Metro Cream if you are allergic to metronidazole or any other ingredient in the formulation.

Tell your healthcare provider if you are pregnant, planning to become pregnant, breastfeeding, or using other prescription skin treatments.

Metro Cream does not cure rosacea, and symptoms may return after treatment.

Protecting your skin from excessive sunlight and identifying personal rosacea triggers may help reduce flare-ups.

Use Metro Cream exactly as prescribed, maintain a gentle skin care routine, and contact your healthcare provider if your symptoms worsen or fail to improve.

Metro Cream is a prescription topical medication used to treat inflammatory bumps and pimples associated with rosacea, a long-term skin condition that commonly affects the face.

It contains metronidazole, an antimicrobial ingredient that helps reduce skin inflammation and improve rosacea-related breakouts.

Metro Cream works mainly through its anti-inflammatory effects. It helps reduce the redness, swelling, and inflammatory lesions associated with rosacea.

Metro Cream 0.75% is usually applied twice daily, in the morning and evening. However, your healthcare provider may recommend a different schedule depending on your skin condition and response to treatment.

Before applying Metro Cream, gently wash the affected skin with a mild cleanser and lukewarm water. Pat your skin dry and allow it to dry completely before applying a thin layer of medication.

Use Metro Cream exactly as prescribed. Do not apply more cream or continue treatment longer than recommended.

How to Apply Metro Cream Correctly

Proper application helps the medication reach the affected skin while reducing the risk of irritation.

Follow these steps when applying Metro Cream:

  1. Wash Your Hands: Clean your hands thoroughly with soap and water before handling the medication.
  2. Clean the Affected Skin: Gently wash your face with a mild, non-irritating cleanser and lukewarm water. Avoid harsh soaps and exfoliating products that may worsen rosacea.
  3. Dry Your Skin Completely: Pat your face dry with a clean, soft towel. Avoid rubbing the skin because this may increase redness and irritation.
  4. Wait Before Applying: Allow your skin to dry completely. Waiting approximately 15 minutes after washing may help reduce stinging or irritation, especially if your skin is sensitive.
  5. Apply a Thin Layer: Place a small amount of Metro Cream on your fingertips. Gently spread a thin layer over the affected areas of your face.
  6. Avoid Sensitive Areas: Keep the medication away from your eyes, lips, mouth, and inside your nose.
  7. Allow the Cream to Absorb: Let the medication absorb into your skin before applying other skin care products.
  8. Wait Before Applying Cosmetics: If you use makeup or other cosmetic products, wait approximately five minutes or until the cream has absorbed.
  9. Wash Your Hands Again: Wash your hands after application to avoid transferring the medication to your eyes or other sensitive areas.
  10. Replace the Cap: Close the medication container tightly after each use.

Metro Cream is intended for external use on the skin only.

Avoid applying the medication to open wounds, severely irritated skin, or areas that your healthcare provider has not instructed you to treat.

Do not apply a thick layer of Metro Cream or use extra medication to make your rosacea improve faster. Excessive application may increase skin irritation without improving treatment results.

How Often Should I Apply Metro Cream?

Metro Cream 0.75% is commonly applied twice daily, usually in the morning and evening.

Your healthcare provider will determine the appropriate application frequency based on the severity of your rosacea and how your skin responds to treatment.

Try to apply Metro Cream at approximately the same time each day.

For example, you may apply the medication in the morning after washing your face and again in the evening before bedtime.

Regular application helps maintain the medication’s anti-inflammatory effects.

However, using Metro Cream more frequently than prescribed will not necessarily improve results.

Applying too much medication may increase dryness, burning, stinging, or redness.

Follow your recommended application schedule, even if your rosacea symptoms begin to improve.

If your skin becomes unusually irritated, contact your healthcare provider before making changes to your treatment.

How Long Should I Use Metro Cream?

The length of treatment depends on the severity of your rosacea and your response to Metro Cream.

Some patients may notice improvements in redness, inflammatory bumps, and skin irritation after approximately three weeks of regular treatment.

However, more noticeable improvements may take six to nine weeks or longer.

Rosacea is a chronic skin condition, meaning symptoms may return even after successful treatment.

For this reason, your healthcare provider may recommend continued treatment to help control inflammation and reduce recurring breakouts.

Metro Cream does not permanently cure rosacea.

Instead, it helps manage inflammatory symptoms and improve the appearance of affected skin.

Do not stop treatment simply because the number of bumps or pimples has decreased.

Continue using Metro Cream for the full treatment period recommended by your healthcare provider.

If your symptoms do not improve after several weeks or become worse, contact your healthcare provider for reassessment.

Can I Apply Makeup After Using Metro Cream?

Yes. Many patients can continue wearing makeup while using Metro Cream.

However, it is important to allow the medication to absorb before applying cosmetic products.

After applying a thin layer of Metro Cream, wait approximately five minutes or until your skin feels dry.

This helps prevent makeup from interfering with the application of the medication.

Choose makeup products that are gentle and suitable for sensitive or rosacea-prone skin.

Products labeled non-comedogenic are less likely to clog pores.

Fragrance-free products may also be less irritating for some patients.

Avoid cosmetics containing harsh exfoliating ingredients or large amounts of alcohol if they cause burning or redness.

Remove makeup gently at the end of the day using a mild cleanser.

Avoid scrubbing your face because friction may trigger additional rosacea irritation.

If makeup causes burning, stinging, or worsening redness while using Metro Cream, stop using the irritating product and contact your healthcare provider if symptoms continue.

Can I Use Moisturizer With Metro Cream?

Yes. A gentle moisturizer may help reduce dryness and support the skin barrier during Metro Cream treatment.

People with rosacea often have sensitive skin that becomes easily irritated by environmental factors and certain skin care products.

A damaged skin barrier may allow moisture to escape more easily, leading to dryness, tightness, and discomfort.

Using a suitable moisturizer can help keep the skin hydrated and reduce irritation.

Choose a fragrance-free moisturizer designed for sensitive skin.

Avoid products that contain ingredients known to trigger your rosacea symptoms.

When using Metro Cream with moisturizer, gently cleanse your face and allow your skin to dry.

Apply Metro Cream as directed and allow it to absorb before applying your moisturizer.

Your healthcare provider may recommend a different order of application depending on the products you use.

Do not mix Metro Cream directly with moisturizer unless your healthcare provider specifically recommends it.

If your skin becomes excessively dry or irritated, ask your healthcare provider whether your skin care routine needs to be adjusted.

Can I Use Other Skin Care Products While Applying Metro Cream?

Some skin care products may be used alongside Metro Cream, but certain ingredients can worsen rosacea symptoms.

People with rosacea often have skin that reacts easily to fragrances, strong cleansers, exfoliating acids, and alcohol-based products.

These ingredients may cause burning, stinging, redness, or dryness.

Avoid using harsh scrubs or exfoliating brushes on inflamed areas.

If you use prescription acne treatments, retinoids, benzoyl peroxide, or other medicated creams, tell your healthcare provider before combining them with Metro Cream.

Some combinations may be appropriate, but others may cause excessive irritation.

Your healthcare provider can recommend a skin care routine that supports treatment without worsening inflammation.

Use a gentle cleanser, a suitable moisturizer, and sunscreen when appropriate.

Tell your healthcare provider about all prescription and over-the-counter skin care products you use before combining them with Metro Cream.

Can I Apply Metro Cream Around My Eyes?

Metro Cream should not be applied directly into the eyes or too close to the eye area.

The medication is intended for external use on the skin.

The tissues around the eyes are sensitive, and accidental contact may cause irritation, burning, or watering.

Avoid applying Metro Cream to the eyelids, eyelashes, or inner corners of the eyes unless your healthcare provider specifically recommends an appropriate treatment.

Some people with rosacea also develop ocular rosacea, a condition that affects the eyes and eyelids.

Ocular rosacea may cause dryness, redness, burning, gritty sensations, and sensitivity to light.

Metro Cream is not intended to be placed inside the eyes or used as a substitute for prescribed eye medication.

If Metro Cream accidentally enters your eyes, rinse thoroughly with plenty of cool water.

Contact your healthcare provider if eye redness, pain, irritation, or blurred vision continues after rinsing.

Seek prompt medical attention if you develop significant eye pain, sensitivity to light, or changes in vision.

What Should I Do If I Miss an Application of Metro Cream?

If you forget to apply Metro Cream, use it as soon as you remember.

However, if it is almost time for your next scheduled application, skip the missed dose and continue with your regular treatment schedule.

Do not apply twice as much cream to make up for a missed application.

Using extra medication will not make rosacea improve faster and may increase skin irritation.

If you frequently forget to apply Metro Cream, consider setting reminders in the morning and evening.

You may also include the medication in your regular skin care routine to help maintain consistent use.

Contact your healthcare provider if you miss several applications or are unsure how to continue treatment.

What Should I Do If My Rosacea Does Not Improve?

Some patients may notice improvements within the first three weeks of Metro Cream treatment.

However, the response varies depending on the severity of rosacea, the number of inflammatory lesions, and individual skin sensitivity.

If your symptoms do not improve after approximately three weeks, contact your healthcare provider for advice.

Your healthcare provider may recommend continuing treatment for a longer period before deciding whether the medication is effective.

Some patients require six to nine weeks or longer to experience more noticeable improvements.

However, if your skin becomes increasingly red, swollen, painful, or irritated, do not ignore these changes.

Worsening symptoms may indicate a reaction to the medication or another skin condition that requires evaluation.

Your healthcare provider may need to review your diagnosis or recommend a different treatment.

Seek medical advice if your rosacea becomes worse, spreads to new areas, or causes significant discomfort during treatment.

How Can I Prevent Rosacea Flare-Ups During Treatment?

Rosacea symptoms can return even when you are using medication.

Certain environmental and lifestyle factors may trigger facial flushing, redness, and inflammatory breakouts.

Common triggers include sunlight, hot weather, cold wind, spicy foods, alcohol, emotional stress, and irritating skin care products.

However, rosacea triggers vary from person to person.

Identifying the factors that worsen your symptoms may help you manage your condition more effectively.

Protect your face from excessive sunlight by using a broad-spectrum sunscreen with SPF 30 or higher.

Choose sunscreen products suitable for sensitive skin.

Avoid washing your face with very hot water because heat may increase flushing and irritation.

Use mild cleansers and avoid scrubbing your skin.

Keep your skin moisturized and avoid products that cause burning or stinging.

If certain foods, drinks, or environmental conditions repeatedly trigger flare-ups, consider limiting your exposure to those specific triggers.

Using Metro Cream consistently and avoiding your personal rosacea triggers may help reduce the frequency and severity of flare-ups.

Important Information When Using Metro Cream

Metro Cream is intended for external use on the skin only.

Do not apply the medication to your eyes, mouth, inside your nose, or other sensitive areas.

If accidental eye contact occurs, rinse thoroughly with plenty of water.

Tell your healthcare provider if you have previously experienced an allergic reaction to metronidazole or other nitroimidazole medications.

Some patients may experience mild dryness, itching, burning, stinging, redness, or irritation at the application site.

If these symptoms become severe or continue to worsen, contact your healthcare provider.

Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before using Metro Cream.

Tell your healthcare provider about other prescription medications and skin care products you currently use.

Metro Cream may require several weeks of regular use before noticeable improvements develop.

Do not apply more medication than prescribed or increase the frequency of application without medical advice.

Keep the medication out of reach of children and store it according to the product instructions.

Use Metro Cream exactly as prescribed, maintain a gentle skin care routine, and follow your healthcare provider’s recommendations to help manage rosacea safely and effectively.

Common Side Effects of Metro Cream (Metronidazole):

  • Dry, scaly, or itchy skin
  • Metallic taste in your mouth
  • Mild burning or stinging
  • Mild skin redness or irritation
  • Nausea
  • Numbness or tingly feeling in your hands or feet

Serious Side Effects of Metro Cream (Metronidazole):

  • Difficulty breathing
  • Hives
  • Severe stinging or burning where the medicine is applied
  • Swelling of your face, lips, tongue, or throat

Metro Cream (Metronidazole) is available in the following forms and strength:

Metro Cream: Cream

  • 0.75%

Metronidazole: Cream

  • 0.75%

Metro Cream is a prescription topical medication used to treat inflammatory bumps and pimples associated with rosacea.

It contains metronidazole, an antimicrobial ingredient that helps reduce skin inflammation and improve certain symptoms of rosacea.

Metro Cream is commonly applied to the affected areas of the face, including the cheeks, nose, forehead, and chin.

Although Metro Cream is generally well tolerated, it may cause skin irritation, allergic reactions, or other unwanted effects in some patients.

Because the medication is applied directly to the skin, only small amounts usually enter the bloodstream.

For this reason, serious side effects associated with metronidazole taken by mouth are generally much less likely with Metro Cream.

Before starting treatment, tell your healthcare provider about any medication allergies, existing skin conditions, blood disorders, pregnancy, breastfeeding, or other medications you currently use.

For External Use Only

Metro Cream should only be applied to the skin.

Do not apply this medication directly into your eyes, mouth, inside your nose, or other sensitive areas.

Metro Cream is specifically formulated to treat inflammatory skin lesions associated with rosacea.

It is not intended to treat infections inside the body, vaginal infections, or eye conditions.

Avoid applying the medication to open wounds or severely damaged skin unless your healthcare provider specifically recommends it.

Before using Metro Cream, gently wash the affected area with a mild cleanser and allow your skin to dry.

Apply a thin layer to the affected skin, following your prescribed treatment schedule.

Avoid using more medication than recommended because excessive application may increase irritation.

If Metro Cream accidentally gets into your eyes, rinse them immediately with plenty of cool water.

Contact your healthcare provider if irritation continues.

Do not swallow Metro Cream. If someone accidentally swallows the medication, contact a poison control center for advice.

Use Metro Cream only on the affected areas of your skin and follow the application instructions provided by your healthcare provider.

Skin Irritation and Local Reactions

Metro Cream may cause mild skin irritation in some patients.

This is particularly important for people with rosacea because their skin is often more sensitive than usual.

Rosacea can weaken the skin’s protective barrier, making it more likely to react to certain medications, cleansers, and cosmetic products.

Possible reactions to Metro Cream include burning, stinging, itching, dryness, redness, and skin discomfort.

Some patients may notice these symptoms shortly after applying the medication.

Others may experience irritation after several days of treatment.

Mild irritation may improve as treatment continues.

However, worsening redness, severe burning, or persistent discomfort may indicate that your skin is not tolerating the medication.

Avoid applying Metro Cream more frequently than prescribed.

Using additional cream will not make rosacea improve faster and may increase skin irritation.

Your healthcare provider may recommend reducing the application frequency or temporarily stopping treatment if significant irritation develops.

If you experience severe burning, persistent redness, swelling, or worsening skin irritation, contact your healthcare provider before continuing treatment.

Allergic Reactions to Metro Cream

Do not use Metro Cream if you have a known allergy to metronidazole or any other ingredient in the medication.

Before starting treatment, tell your healthcare provider if you have previously experienced an allergic reaction to metronidazole or other nitroimidazole medications.

Metro Cream contains active and inactive ingredients that may cause allergic reactions in sensitive individuals.

An allergic reaction can develop when the immune system responds to a substance it considers harmful.

Possible symptoms include itching, hives, skin rash, redness, or swelling.

These symptoms may resemble rosacea-related irritation, making it important to recognize changes that occur after applying the medication.

Some people may develop contact dermatitis, which causes inflammation after the skin comes into contact with an irritating or allergy-causing substance.

Contact dermatitis may cause redness, itching, swelling, or a rash at the application site.

In rare cases, a serious allergic reaction may cause swelling of the face, lips, tongue, or throat.

Difficulty breathing or swallowing may also occur.

Stop using Metro Cream and seek emergency medical attention if you develop difficulty breathing or swelling of the tongue or throat.

If you develop a new rash or persistent itching, contact your healthcare provider for an evaluation.

Avoid Contact With the Eyes

Metro Cream is not intended for use in or directly around the eyes.

The eyes contain delicate tissues that may become irritated when exposed to topical skin medications.

Metronidazole applied to the skin has been associated with excessive tearing and eye irritation.

Accidental eye contact may cause burning, redness, watering, or discomfort.

When applying Metro Cream to your face, avoid placing the medication too close to your eyelids, eyelashes, or inner corners of the eyes.

Apply the cream carefully using clean fingertips.

Wash your hands after application to reduce the risk of transferring medication into your eyes.

If Metro Cream accidentally gets into your eyes, rinse them immediately with plenty of cool water.

Avoid rubbing your eyes because this may make irritation worse.

If you develop persistent redness, eye pain, or blurred vision, contact your healthcare provider.

Some patients with rosacea also develop ocular rosacea, which affects the eyes and eyelids.

Metro Cream should not be used as a substitute for treatment specifically prescribed for ocular rosacea.

Seek prompt medical attention if you experience significant eye pain, sensitivity to light, or changes in vision.

Medication and Supplement Interactions

Tell your healthcare provider about all medications and supplements you currently use before starting Metro Cream.

This includes prescription medications, over-the-counter products, vitamins, herbal supplements, and other topical skin treatments.

Although Metro Cream is applied to the skin, a small amount of metronidazole may enter the bloodstream.

For this reason, certain medication interactions may still need to be considered.

Metronidazole taken by mouth can increase the effects of certain blood-thinning medications, including warfarin.

Warfarin helps prevent harmful blood clots by reducing the blood’s ability to clot.

When its effects become too strong, the risk of bruising and bleeding may increase.

However, it is not known whether topical Metro Cream causes the same interaction because systemic absorption is much lower.

If you take warfarin or another anticoagulant, inform your healthcare provider before using Metro Cream.

Your healthcare provider can determine whether additional monitoring is necessary.

Other topical products, including medicated acne treatments, exfoliating creams, and alcohol-based skin preparations, may increase irritation when used alongside Metro Cream.

Do not combine Metro Cream with other prescription skin treatments without discussing their use with your healthcare provider.

Pregnancy and Metro Cream

Tell your healthcare provider if you are pregnant, planning to become pregnant, or think you may be pregnant before using Metro Cream.

There is limited information about the safety of topical metronidazole during human pregnancy.

Metronidazole is absorbed into the bloodstream in much smaller amounts when applied to the skin than when taken by mouth.

However, limited absorption does not establish that the medication is completely risk-free during pregnancy.

Your healthcare provider will consider the severity of your rosacea, the expected benefits of treatment, and any potential risks.

Rosacea may become more noticeable during pregnancy because hormonal changes can affect skin sensitivity and blood vessels.

Some patients may experience increased facial redness, flushing, or inflammatory breakouts.

Your healthcare provider can determine whether Metro Cream is an appropriate treatment or whether another approach would be preferable.

Use Metro Cream during pregnancy only after discussing its benefits and potential risks with your healthcare provider.

If you become pregnant while using Metro Cream, contact your healthcare provider to review your treatment plan.

Breastfeeding and Metro Cream

Consult your healthcare provider before using Metro Cream if you are breastfeeding.

Metronidazole taken by mouth is known to pass into human breast milk.

However, the amount that may enter breast milk after topical application is expected to be much lower because relatively little medication reaches the bloodstream.

The available information is limited, so the safety of Metro Cream during breastfeeding has not been fully established.

Your healthcare provider will consider the importance of rosacea treatment, the amount of medication used, and any potential risks to your baby.

If Metro Cream is prescribed during breastfeeding, avoid applying it directly to your nipples or surrounding breast area.

This helps prevent your baby from accidentally swallowing medication during feeding.

Wash your hands thoroughly after applying Metro Cream.

Avoid allowing your baby to come into direct contact with skin where the medication has recently been applied.

Breastfeeding does not automatically need to stop during Metro Cream treatment, but you should discuss its suitability with your healthcare provider.

Blood Disorders and Metro Cream

Tell your healthcare provider if you have a history of blood disorders before using Metro Cream.

Blood disorders are conditions that affect the number or function of blood cells.

These include conditions involving red blood cells, white blood cells, or platelets.

Red blood cells carry oxygen throughout the body, while white blood cells help protect against infections.

Platelets help the blood clot and prevent excessive bleeding.

Metronidazole taken by mouth has occasionally been associated with changes in blood cell counts, including a reduction in certain white blood cells.

This condition is called leukopenia.

A low white blood cell count may make it harder for the body to fight certain infections.

However, these effects are not established as common side effects of Metro Cream.

Because Metro Cream is applied to the skin, exposure throughout the body is much lower than with oral metronidazole.

Even so, the prescribing information recommends caution in patients with current or previous blood disorders.

Your healthcare provider may review your medical history before recommending treatment.

Tell your healthcare provider if you have a blood disorder or have previously experienced abnormal blood cell counts while taking medication.

Neurological Symptoms and Nerve Problems

Metronidazole taken by mouth or given through injection has occasionally been associated with neurological complications.

These complications may affect the brain, spinal cord, or peripheral nerves.

Peripheral nerves carry signals between the brain, spinal cord, and other parts of the body.

Damage to these nerves is called peripheral neuropathy.

Symptoms may include numbness, tingling, burning sensations, or pain in the hands and feet.

More serious neurological complications, including seizures and confusion, have been reported with systemic metronidazole treatment.

However, these effects are much less likely with Metro Cream because only small amounts of medication enter the bloodstream.

Rare reports of tingling or numbness have occurred during topical metronidazole use.

Tell your healthcare provider if you have an existing neurological condition or a history of nerve problems.

If you notice unusual numbness, tingling, or other new neurological symptoms, stop using Metro Cream and contact your healthcare provider promptly.

Your healthcare provider can determine whether the symptoms may be related to treatment or another medical condition.

Seek emergency medical attention if you experience seizures, sudden severe confusion, or other serious neurological symptoms.

Alcohol Consumption During Metro Cream Treatment

Tell your healthcare provider if you regularly consume alcohol while using Metro Cream.

Metronidazole taken by mouth has traditionally been associated with a possible unpleasant reaction when combined with alcohol.

This is sometimes called a disulfiram-like reaction.

Possible symptoms include facial flushing, headache, nausea, vomiting, and abdominal discomfort.

However, evidence that metronidazole consistently causes this reaction is limited and conflicting.

The interaction has not been clearly established with topical Metro Cream.

Because only small amounts of metronidazole enter the bloodstream after skin application, the risk of a systemic interaction is expected to be much lower than with oral treatment.

Alcohol may also trigger rosacea flare-ups in some patients.

For example, drinking alcohol may cause facial flushing, increased redness, or a warm sensation in the cheeks.

These reactions may occur because alcohol can affect blood vessels near the skin’s surface.

If alcohol regularly worsens your rosacea symptoms, avoiding or limiting it may help reduce flare-ups.

Ask your healthcare provider whether you should avoid alcohol while using Metro Cream, especially if alcohol triggers your rosacea symptoms.

Existing Skin Conditions and Sensitive Skin

Tell your healthcare provider if you have eczema, psoriasis, contact dermatitis, or another skin condition before using Metro Cream.

Some inflammatory skin conditions can resemble rosacea.

For example, eczema may cause red, dry, itchy patches, while contact dermatitis may develop after exposure to irritating skin care products.

Rosacea can also cause burning, stinging, redness, and skin sensitivity.

Because these conditions may share similar symptoms, an accurate diagnosis is important.

Metro Cream is specifically prescribed to treat inflammatory lesions associated with rosacea.

It does not treat every condition that causes facial redness or irritation.

Using Metro Cream for an unrelated skin condition may delay appropriate treatment.

Patients with sensitive skin may also react more easily to certain ingredients in topical medications.

Avoid applying Metro Cream to severely damaged skin or open wounds unless your healthcare provider specifically recommends it.

Contact your healthcare provider if your skin becomes increasingly irritated or develops unusual symptoms during treatment.

Sun Exposure and Rosacea Flare-Ups

Sunlight is a common trigger for rosacea flare-ups.

Exposure to ultraviolet radiation and heat may increase facial redness, flushing, and inflammation.

Some patients notice that their rosacea becomes worse after spending time outdoors, especially during hot or sunny weather.

Metro Cream helps treat inflammatory rosacea lesions, but it does not protect the skin from ultraviolet radiation.

For this reason, sun protection remains important during treatment.

Use a broad-spectrum sunscreen with SPF 30 or higher when appropriate.

Choose a sunscreen suitable for sensitive or rosacea-prone skin.

Wear a wide-brimmed hat and seek shade when sunlight is strongest.

Avoid tanning beds and excessive exposure to sunlamps.

If sunscreen or another skin care product causes burning or stinging, ask your healthcare provider about gentler alternatives.

Protecting your skin from excessive sunlight may help reduce rosacea flare-ups while using Metro Cream.

Use in Children

The safety and effectiveness of Metro Cream have not been established in pediatric patients.

Rosacea is more commonly diagnosed in adults, although similar inflammatory skin conditions may occur in children.

Facial redness, bumps, or irritation in children can have several causes.

These may include acne, eczema, allergic reactions, and certain skin infections.

Because treatment depends on the underlying condition, a proper medical evaluation is important.

Do not use Metro Cream on a child without consulting a healthcare provider.

Your healthcare provider can determine whether the medication is appropriate or whether another treatment is needed.

Keep the medication out of reach of children to prevent accidental swallowing or misuse.

Do not give Metro Cream to children unless a healthcare provider specifically recommends it.

Complete the Recommended Treatment

Use Metro Cream exactly as prescribed by your healthcare provider.

Metro Cream 0.75% is commonly applied twice daily, in the morning and evening.

Before each application, gently wash and dry the affected skin.

Apply a thin layer of medication to the areas affected by inflammatory rosacea.

Some patients may begin to notice fewer bumps and less inflammation after approximately three weeks.

However, more noticeable improvement may take six to nine weeks or longer.

Rosacea is a chronic condition, meaning symptoms may return even after successful treatment.

Your healthcare provider may recommend continued treatment to help keep inflammatory breakouts under control.

Do not stop applying Metro Cream simply because your skin looks better.

Similarly, do not increase the application frequency or use more cream than recommended.

Excessive use may increase skin irritation without improving treatment results.

Follow your prescribed treatment schedule and do not stop, extend, or change treatment without medical advice.

Avoid Irritating Skin Care Products

People with rosacea often have sensitive skin that reacts easily to certain ingredients.

Harsh cleansers, exfoliating scrubs, fragranced products, and alcohol-based skin preparations may worsen irritation.

These products can affect the skin’s protective barrier, making it more sensitive to environmental triggers.

Using several medicated products at the same time may also increase dryness, burning, or redness.

Choose gentle, fragrance-free skin care products whenever possible.

Wash your face with lukewarm water rather than very hot water.

Avoid rubbing or scrubbing the affected skin.

If you use makeup, allow Metro Cream to absorb before applying cosmetic products.

A gentle moisturizer may help reduce dryness and support the skin barrier.

Tell your healthcare provider if you are using prescription acne treatments, retinoids, exfoliating acids, or other medicated creams.

Your healthcare provider can help determine which products are suitable for use alongside Metro Cream.

Stop using skin care products that cause significant burning, stinging, or worsening redness, and seek medical advice if the irritation continues.

When to Contact Your Healthcare Provider

Contact your healthcare provider if your rosacea symptoms become worse or do not improve after several weeks of Metro Cream treatment.

You should also seek medical advice if you develop persistent burning, severe dryness, increasing redness, swelling, or an unusual rash.

These symptoms may indicate skin irritation, an allergic reaction, or another condition that requires evaluation.

If you develop persistent numbness, tingling, or other unusual neurological symptoms, stop using Metro Cream and contact your healthcare provider promptly.

Your healthcare provider may recommend adjusting the application frequency, temporarily stopping treatment, or using another medication.

Seek emergency medical attention if you experience difficulty breathing, swelling of the tongue or throat, seizures, or sudden severe confusion.

Continue using Metro Cream according to your healthcare provider’s instructions unless you develop symptoms that require stopping the medication.

Keep your skin care routine gentle, avoid known rosacea triggers, and attend recommended follow-up appointments to monitor your response to treatment.

How Long Does It Take for Metro Cream to Work?

Metro Cream may take several weeks to show noticeable improvements in rosacea symptoms. Some patients begin to see fewer inflammatory bumps, less redness, and reduced skin irritation after approximately three weeks of regular use. However, it may take six to nine weeks or longer to experience the full benefits. The results depend on the severity of your rosacea and how your skin responds to treatment. Continue using Metro Cream as prescribed by your healthcare provider, even if improvements are gradual. If your symptoms become worse or do not improve after several weeks, contact your healthcare provider for advice.

Can I Use Metro Cream If I Am Pregnant or Breastfeeding?

Consult your healthcare provider before using Metro Cream if you are pregnant, planning to become pregnant, or breastfeeding. There is limited information about its safety during pregnancy and breastfeeding. Although Metro Cream is applied directly to the skin and only small amounts of the medication enter the bloodstream, potential risks should still be considered. Your healthcare provider will determine whether the expected benefits outweigh the possible risks. If you are breastfeeding, avoid applying Metro Cream to areas where your baby could come into direct contact with the medication. Use Metro Cream during pregnancy or breastfeeding only after discussing its suitability with your healthcare provider.

Can Metro Cream Be Used on Other Parts of the Body Besides the Face?

Metro Cream is primarily prescribed to treat inflammatory rosacea affecting the face, including the cheeks, nose, forehead, and chin. However, your healthcare provider may recommend applying it to other affected areas when medically appropriate. Metro Cream is intended for external use on the skin only and should not be applied to the eyes, mouth, inside the nose, or other sensitive areas. Do not use Metro Cream on other parts of your body without consulting your healthcare provider, as redness, bumps, or irritation outside the face may be caused by a different skin condition that requires another treatment.

Is Metro Cream Safe to Use Long-Term?

Metro Cream may be used for extended periods when recommended and monitored by your healthcare provider. Rosacea is a chronic skin condition, meaning symptoms may return even after successful treatment. Some patients require ongoing treatment to help control inflammation and prevent recurring breakouts. Metro Cream is generally well tolerated, but prolonged use may cause dryness, burning, stinging, or skin irritation in some people. Your healthcare provider will assess your response to treatment and determine whether continued use is necessary. Do not extend treatment or change your application schedule without consulting your healthcare provider.

REVIEWS

Additional Information Book
Generic name:

Metronidazole

Formulation:

Cream

Strength(s):

0.75%

Quantities Available:

30g, 45g, 90g

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Metro Cream can I order at once from a Canadian pharmacy?

When ordering Metro Cream (metronidazole) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Metro Cream is commonly prescribed in a 0.75% concentration, applied once or twice daily to the affected skin area. The amount of cream you will order for a 90-day supply depends on the frequency of application and the area to be treated.

Do you sell metronidazole?

Yes, we sell metronidazole on our website. You can enjoy low prices when you order through us. To purchase metronidazole, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You can submit your prescription by mailing it to us, faxing it, or uploading it through your online account.

Do you offer shipping of Metro Cream (metronidazole) to the United States?

Yes, we ship Metro Cream (metronidazole) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Metro Cream (Metronidazole). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Metro Cream (Metronidazole).