Melanocyl (Methoxsalen)

Indications

Melanocyl is a medication used in the treatment of certain skin diseases like vitiligo. It contains Methoxsalen, which is a skin-sensitizing agent that is used along with ultraviolet light for the treatment of skin diseases such as vitiligo. It belongs to the group of medicines called Antipsoriatics. The medication is prescribed along with regulated quantities of ultraviolet light or sunlight for its effective use.

Methoxsalen works by decreasing the number of cells the skin makes. It is activated by exposure to ultraviolet light, which makes the skin more sensitive to sunlight. Melanocyl works in combination with ultraviolet light to treat skin conditions by reducing the number of skin cells and helping to even out skin color.

Use and Dosage

To take methoxsalen, you should swallow an uncoated tablet with low fat food or milk, as instructed by your doctor. Typically, the tablet is taken 90 minutes to 2 hours before UVA light treatment. Taking methoxsalen with food can help with better absorption of the medication and reduce nausea.

The amount of methoxsalen prescribed depends on your body weight, medical condition, and response to treatment. The UVA light treatment's duration and frequency depend on your skin type and how you respond to treatment. Typically, you will receive UVA light treatments 2 to 4 times a week initially, and less often as your condition improves.

After taking the medication, you should wear UVA-blocking wrap-around sunglasses during daylight hours for 24 hours, reducing methoxsalen binding to your lenses, which could cause cataracts. During daylight hours, avoid sunlight on your skin or lips for at least 8 hours after taking methoxsalen, as exposure to UVA rays could damage your skin and lead to sunburn. If you cannot avoid sunlight, wear protective clothing or sunscreen that blocks UVA light on the skin, as advised by your doctor or pharmacist. Do not apply sunscreen to areas of your skin affected by psoriasis until after the UVA light treatment.

During the UVA light treatment, you must follow all instructions given by your healthcare provider. After the treatment, avoid sunbathing for 48 hours to avoid severe burns. Please speak to your doctor for more information.

Side Effects

Common Side Effects of Melanocyl (Methoxsalen):

• Low blood pressure
• Dryness
• Itching
• Redness of the skin
• Nausea
• Trouble sleeping (insomnia)
• Depression

Serious Side Effects of Melanocyl (Methoxsalen):

• Blistering and peeling of skin
• Darkening of skin
• Low blood pressure
• Nausea
• Redness of the skin
• Swelling in the arms or legs
• Trouble sleeping

Forms and Strength

Melanocyl (Methoxsalen) is available in the following forms and strength:

Melthoxalen: Uncoated Tablet

• 10 mg

Cautions

• Melanocyl is a prescription medication and should only be used under the supervision of a qualified healthcare professional.
• Melanocyl may interact with other drugs. Inform your doctor of all the products you use (including prescription/nonprescription drugs and herbal supplements) to avoid potential drug interactions.
• Melanocyl should be used with caution during pregnancy and breastfeeding. Birth control methods should be employed since the effects of PUVA therapy (treatment with Methoxsalen) on the unborn or nursing baby are not known.
• Melanocyl may cause side effects, some of which could be serious. This is not a complete list of possible side effects and report any unusual symptoms to your doctor immediately.
• Melanocyl should be stored at room temperature away from light and moisture and kept out of the reach of children.
• Melanocyl may increase the risk of skin cancer and should only be used under the supervision of a qualified healthcare professional.
• Melanocyl may make the skin more sensitive to sunlight, so individuals should avoid exposure to natural or artificial sunlight (such as tanning beds) during treatment and for at least 24 hours after taking the medication.
• Melanocyl may cause skin irritation, redness, and itching. Individuals should report any skin reactions to their doctor immediately.
• Melanocyl may cause changes in skin color and should be used with caution in individuals with a history of melanoma or other skin cancers.
• Individuals with a history of liver or kidney disease should use Melanocyl with caution.

Frequently Asked Questions (FAQ)

Is Methoxsalen safe for everyone to use?

No, Methoxsalen may not be safe for everyone to use. It can interact with other drugs and may have risks associated with its use. Consult with a qualified healthcare professional to determine if Methoxsalen is safe and appropriate for you.

How long does it take to see results from Methoxsalen treatment?

The length of time it takes to see results from Methoxsalen treatment can vary depending on the condition being treated and individual patient factors. It may take several weeks or months to see improvement.

Is Methoxsalen available over the counter?

No, Methoxsalen is not available over the counter. It is a prescription medication that must be obtained from a qualified healthcare professional.

Resources

• https://www.webmd.com/drugs/2/drug-6957-1257/methoxsalen-oral/methoxsalen-rapid-oral/details
• https://www.practo.com/medicine-info/melanocyl-solution-46983
• https://www.rxlist.com/8-mop-drug.htm
• https://www.medindia.net/doctors/drug_information/methoxsalen.htm
• https://www.1mg.com/drugs/melanocyl-tablet-115561
• https://www.drugs.com/cons/methoxsalen-topical.html