MacroBID (Nitrofurantoin Monohydrate) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet


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Prescription Prescription Required FormationFormulation: Tablet

Nitrofurantoin Monohydrate

(Generic Alternative)

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MacroBID generically known as Nitrofurantoin Monohydrate is an antibiotic drug used to treat bacterial infections of the urinary tract. It works by killing the bacteria in the bladder that cause these painful and uncomfortable illnesses. It is commonly prescribed for treating uncomplicated urinary tract infections (UTIs) and is a safe and effective treatment option for those suffering from this infection.

Nitrofurantoin belongs to a class of medications known as antimicrobials or antibiotics, which are a group of drugs that work in a similar manner to treat similar conditions. Specifically, Nitrofurantoin is used to eliminate the bacteria responsible for urinary tract infections. It should be noted that this medication is only effective against certain kinds of bacteria.

Nitrofurantoin Monohydrate is especially useful for treating chronic or recurring bladder infections. This prescription medicine is available in the form of a capsule, and it is taken orally. In addition to being an effective treatment for urinary tract infections, MacroBID may also be used to prevent potential infections.

Uses and Dosage

When taking MacroBID (Nitrofurantoin Monohydrate) capsules, it is important to swallow them whole and not crush, chew, or break them. Nitrofurantoin is best taken with food or milk to help reduce stomach upset and maximize absorption into the body.

You must take MacroBID exactly as your doctor has prescribed and not take more than the prescribed amount. It is important to take MacroBID at evenly spaced times for the best effect. It should not be opened as this may interfere with the nitrofurantoin release mechanism.

The usual recommended dosage for adults is 100 mg taken every 12 hours for 7 days. The dosage may be increased up to 200 mg every 12 hours depending on the severity of the UTI. In some cases, a higher dose of 100 mg taken four times a day for severe infections may be prescribed. For prevention of urinary tract infections, adults and teenagers can take 50-100 mg once a day. Children should take a dose based on their body weight and as prescribed by their doctor.

Side Effect

Common Side Effects of Nitrofurantoin Can Include:

  • Diarrhea
  • Dizziness
  • Drowsiness
  • Headache
  • Loss of appetite
  • Nausea
  • Numbness in your hands and feet
  • Pain in your hands and feet
  • Stomach pain
  • Vomiting
  • Weakness

Serious Side Effects of Nitrofurantoin Monohydrate Include:

  • Lung inflammation
    • Chest pain
    • Chills
    • Cough
    • Fever
    • Shortness of breath
    • Tiredness
  • Liver problems
    • Dark urine
    • Itching
    • Loss of appetite
    • Nausea or vomiting
    • Yellowing of your skin or the whites of your eyes
  • Nerve damage
    • Muscle weakness
    • Numbness or tingling in your hands and feet
  • Hemolysis (red blood cell damage)
    • Pale skin
    • Tiredness
    • Weakness
  • Diarrhea
    • Bloody stools
    • Stomach pain
    • Very loose or watery stools

Form and Strength

MacroBID and its generic alternative Nitrofurantoin Monohydrate are available in the following forms and strengths:

MacroBID: Capsule

  • 100 mg

Nitrofurantoin Monohydrate: Capsule

  • 100 mg


When taking MacroBID (Nitrofurantoin Monohydrate), there are certain cautions to consider.

  • Patients taking this drug may be at risk of developing lung inflammation, a rare side effect which is more likely to occur with prolonged use of the drug.
  • Liver inflammation or injury is a potential complication, and those on long-term treatment should have their liver monitored regularly through blood tests.
  • The use of macrobid has the potential to cause hemolysis, a form of red blood cell damage. Symptoms of hemolysis may include fatigue, decreased strength, and paleness of the skin. Once the medication is discontinued, the hemolysis should subside.
  • Patients should be monitored for signs of anemia and other signs of adverse reactions while taking this medication.
  • Nitrofurantoin Monohydrate is not recommended for use in children under the age of 12 years, as it can cause bone marrow suppression and blood dyscrasias. If a child needs to take this medication, it should be done under a doctor's supervision.
  • It has been associated with an increased risk of birth defects when taken during pregnancy, so it should be avoided in pregnant or nursing mothers.

Frequently Asked Questions (FAQ)

How do I take MacroBID?

MacroBID should be taken orally with a full glass of water. Take the capsules whole and do not crush, chew, or break them. It should be taken at evenly spaced times for best effect.

What should I do if I miss a dose of MacroBID?

If you miss a dose of MacroBID, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and resume your regular dosing schedule. Do not double dose to make up for a missed dose.

What should I do if I overdose on MacroBID?

If you suspect an overdose, contact your local poison control center, or seek medical attention immediately.

Can I drink alcohol while taking MacroBID?

It is not recommended to drink alcohol while taking MacroBID, as it can increase the risk of side effects. You should speak to your doctor if you want to drink alcohol while taking MacroBID.


Additional information

Generic name:

Nitrofurantoin Monohydrate





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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about MacroBID (Nitrofurantoin Monohydrate). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about MacroBID (Nitrofurantoin Monohydrate).