Prescription Required
Formulation: Tablet
Prescription Required
Formulation: Tablet
(Generic Alternative)
Select the prescribed dosage
Select the quantity to see the price.
* This price includes a dispensing fee, medical review fee, and packing fee.
Shipped and delivered directly to your doorstep
Pyrazinamide contains the active ingredient pyrazinamide. It is a prescription antibiotic used as part of combination therapy for tuberculosis (TB) caused by susceptible strains of Mycobacterium tuberculosis.
Tuberculosis is a bacterial infection caused by Mycobacterium tuberculosis. It most commonly affects the lungs, but it can also spread to other parts of the body.
Common symptoms of active pulmonary tuberculosis may include:
Pyrazinamide is not usually used alone. It is typically combined with other anti-tuberculosis medications, such as isoniazid, rifampin, and ethambutol, especially during the early phase of treatment.
Tuberculosis bacteria can be difficult to eliminate because some bacteria remain active while others grow very slowly or survive in areas where conditions are less favorable for bacterial growth.
Using several anti-tuberculosis medications together helps:
Pyrazinamide is particularly important during the initial phase of tuberculosis treatment, when the number of bacteria in the body may be highest.
Pyrazinamide belongs to a group of medications known as first-line anti-tuberculosis drugs.
Pyrazinamide enters tuberculosis bacteria and is converted into its active form, pyrazinoic acid, by a bacterial enzyme.
Pyrazinoic acid is especially active in the acidic environments where some tuberculosis bacteria can survive, including inside certain immune cells.
Its exact mechanism is not completely understood, but it appears to interfere with important bacterial functions, including membrane activity and energy production. These effects help stop the bacteria from surviving and multiplying.
Pyrazinamide is commonly used during the first part of a multi-drug tuberculosis treatment plan.
Its ability to act against bacteria that may be difficult for some other TB medications to reach or eliminate makes it an important part of combination therapy.
The exact treatment regimen and length of therapy depend on factors such as:
Tuberculosis treatment usually requires several medications taken for many months.
It is important to take pyrazinamide and the other prescribed TB medications exactly as directed. Missing doses or stopping treatment too early can allow the bacteria to survive and may increase the risk of drug-resistant tuberculosis.
Your healthcare provider will determine how long pyrazinamide should be used as part of your treatment plan.
Pyrazinamide is taken by mouth as a tablet and should always be used in combination with other tuberculosis medications.
It is commonly taken once daily, but some tuberculosis treatment plans may use larger doses given twice weekly under medical supervision.
Take pyrazinamide exactly as prescribed by your healthcare provider. It may be taken with or without food. Try to take each dose at about the same time on scheduled treatment days to help you remember.
The dose of pyrazinamide is usually based on body weight, the tuberculosis treatment regimen, and other individual factors.
A common adult daily dose is 15 to 30 mg/kg once daily. In some supervised treatment plans, pyrazinamide may instead be given at a higher dose twice weekly.
Your healthcare provider will determine the correct dose for you.
Do not increase or decrease your dose, change how often you take pyrazinamide, or stop treatment without speaking with your healthcare provider.
Tuberculosis treatment requires several medications to be taken for a specific length of time. Missing doses or stopping treatment early can allow tuberculosis bacteria to survive and may increase the risk of drug-resistant tuberculosis.
If you miss a dose of pyrazinamide, take it as soon as you remember unless it is almost time for your next scheduled dose.
If your next dose is approaching, skip the missed dose and continue with your regular treatment schedule.
Do not take two doses at the same time or take extra medication to make up for a missed dose.
Because pyrazinamide is part of a combination tuberculosis treatment plan, repeated missed doses can affect how well treatment works. If you miss more than one dose, are unsure when to take your next dose, or are following a twice-weekly treatment schedule, contact your healthcare provider or TB treatment team for instructions.
Your healthcare provider may adjust your dose depending on:
Your weight may also be checked during treatment because weight-based doses may need to be adjusted if your weight changes.
Take all tuberculosis medications exactly as prescribed, even if you begin feeling better.
Pyrazinamide is commonly used during the initial phase of tuberculosis treatment, often during the first several weeks or months of a multidrug treatment regimen.
Do not stop pyrazinamide or any other tuberculosis medication unless your healthcare provider specifically tells you to.
Pyrazinamide (Pyrazinamide) is available in the following forms and strength:
Tell your healthcare provider or pharmacist if you are allergic to pyrazinamide or any ingredient in the medication before starting treatment.
Some tablets may contain inactive ingredients that can cause allergic reactions in sensitive people. Your pharmacist can provide more information about the ingredients in your specific product.
Seek immediate medical attention if you develop symptoms of a serious allergic reaction, such as hives, swelling of the face or throat, or difficulty breathing.
Pyrazinamide can affect the liver and may cause serious liver problems in some people.
Tell your healthcare provider if you have liver disease or a history of liver problems before taking pyrazinamide. Your healthcare provider may order blood tests before and during treatment to monitor how well your liver is working.
Contact your healthcare provider promptly if you develop symptoms such as:
Avoid or limit alcohol while taking pyrazinamide, especially if your healthcare provider has advised you not to drink.
Alcohol can place additional stress on the liver and may increase the risk of liver damage during treatment.
Tell your healthcare provider about your alcohol use before starting pyrazinamide.
Tell your healthcare provider if you have kidney disease or reduced kidney function.
Kidney problems can affect how pyrazinamide and its breakdown products are removed from the body. Your dose or treatment schedule may need to be adjusted.
Pyrazinamide can increase the amount of uric acid in the blood, which may trigger or worsen gout.
Tell your healthcare provider if you have:
Contact your healthcare provider if you develop sudden joint pain, redness, or swelling during treatment.
Tell your healthcare provider if you have diabetes before taking pyrazinamide.
Tuberculosis treatment and changes in your overall health may affect blood sugar control. Your healthcare provider may recommend closer monitoring during treatment.
Tell your healthcare provider that you are being treated for tuberculosis before receiving any vaccines.
Some vaccines may need to be timed differently during tuberculosis treatment. Your healthcare provider can advise you about which vaccines are appropriate and when they should be given.
Tell your healthcare provider if you are pregnant or planning to become pregnant before taking pyrazinamide.
Tuberculosis itself can pose serious risks during pregnancy, so treatment decisions should balance the benefits of treating the infection against any potential medication risks.
Do not stop tuberculosis treatment because of pregnancy without speaking with your healthcare provider.
Pyrazinamide can pass into breast milk in small amounts.
If you are breastfeeding, talk with your healthcare provider about the benefits and possible risks of continuing treatment. Your healthcare provider can determine whether pyrazinamide is appropriate based on your tuberculosis treatment plan and your baby’s health.
Tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, supplements, and herbal products you use.
Because pyrazinamide is usually taken with several other tuberculosis medications, your healthcare provider may need to review your full treatment plan for possible drug interactions and overlapping side effects.
Pyrazinamide can generally be taken with or without food. Try to take it at about the same time on each scheduled treatment day to help maintain a consistent routine. If pyrazinamide causes stomach upset, taking it with food may make it easier to tolerate. Follow the specific instructions provided by your healthcare provider or pharmacist.
For many people with drug-susceptible active tuberculosis, pyrazinamide is mainly used during the initial phase of treatment, which commonly lasts about 2 months. Pyrazinamide is particularly useful early in treatment because it helps kill tuberculosis bacteria that may be difficult for some other TB medications to eliminate. After the initial phase, treatment usually continues with other anti-tuberculosis medications for several more months. The exact length of treatment depends on the type of TB, drug susceptibility, response to treatment, and other individual factors. Do not stop pyrazinamide unless your healthcare provider tells you to.
Tuberculosis treatment usually involves several medications taken together over a period of several months. For many standard treatment plans for drug-susceptible active TB, pyrazinamide is taken during the first 2 months of treatment. Other tuberculosis medications are then continued for the remainder of the treatment course, which commonly lasts about 6 months in total. Treatment may be longer or different if the tuberculosis bacteria are drug-resistant, the infection affects certain parts of the body, or the patient does not respond as expected. Always complete the full TB treatment plan prescribed by your healthcare provider.
| Generic name: | Pyrazinamide |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 500mg |
| Quantities Available: | 100 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Pyrazinamide from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Pyrazinamide is commonly prescribed in dosages of 500 mg, taken once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).
Yes, we sell Pyrazinamide on our website. You can enjoy low prices when you order through us. To purchase Pyrazinamide, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You have the option to submit your prescription by mailing it to us, faxing it, or uploading it through your online account.
Yes, we ship Pyrazinamide (pyrazinamide) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Pyrazinamide (Pyrazinamide). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Pyrazinamide (Pyrazinamide).
REVIEWS