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Lioresal Intrathecal (generically known as Baclofen) is a prescription medication used to treat severe spasticity caused by injury to the spinal cord or multiple sclerosis. Baclofen belongs to two groups of medications known as muscle relaxants and antispastics. It is used to treat spasticity (uncontrolled muscle movements) caused by multiple sclerosis, spinal cord injuries, or spinal cord diseases.
Baclofen works by decreasing the activity of certain nerve receptors in the spinal cord, which leads to reduced muscle spasms and increased muscle relaxation. By delivering the drug directly into the spinal fluid, Lioresal Intrathecal can provide more effective relief of severe spasticity that cannot be adequately managed through oral medications.
Lioresal Intrathecal (baclofen injection) ampules are intended for single-use only and are packaged in 0.05 mg/1 mL (50 mcg/mL) doses. They are used in a pump that is surgically implanted under the skin of your abdomen, which delivers the medication directly into the spinal fluid through a catheter.
Your healthcare provider will determine the appropriate dosage for you based on your individual needs. Follow the specific instructions provided by your healthcare provider for the use of Lioresal Intrathecal. You should not attempt to administer the medication on your own without proper training and instruction.
Note that abrupt withdrawal of intrathecal baclofen may occur in patients using the drug over two months, which may result in a hypermetabolic state with potentially fatal consequences. Monitoring for early clinical and laboratory signs of withdrawal is necessary. If you have any questions or concerns about the use of Lioresal Intrathecal ampules, you should consult with your healthcare provider.
Lioresal Intrathecal can be given exactly as prescribed by your doctor. Keep your appointments to have the pump refilled, otherwise spasms may recur.
Lioresal Intrathecal (Baclofen) is available in the following forms and strength:
No, Lioresal Intrathecal should not be abruptly discontinued, as this can lead to withdrawal symptoms. Patients should work with their healthcare provider to gradually taper off the medication if needed.
Patients should contact their healthcare provider immediately if they experience any side effects while on Lioresal Intrathecal.
Yes, Lioresal Intrathecal can be used in children with severe spasticity caused by injury to the spinal cord or multiple sclerosis. However, dosing and administration may be different in children than in adults.
The frequency of pump refills depends on the individual patient’s dosage and infusion rate. Patients typically need to have their pump refilled every few weeks to several months.
| Generic name: | Baclofen |
|---|---|
| Formulation: | Ampule |
| Strength(s): | 2mg/mL |
| Quantities Available: | 25mL |
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Lioresal Intrathecal (Baclofen). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Lioresal Intrathecal (Baclofen).
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