Januvia (Sitagliptin Phosphate)

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Januvia Brand
Dosage Quantity & Price
Sitagliptin Phosphate (Generic alternate to Januvia) Generic
Dosage Quantity & Price
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Januvia is a once-daily prescription medication used to treat type 2 diabetes. The active ingredient in Januvia is Sitagliptin Phosphate. Sitagliptin Phosphate is part of a class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the amount of insulin your body produces naturally and decreasing the amount of sugar produced by your liver.

Januvia works differently than other diabetes medications because it only affects certain areas in the body, such as increasing insulin production and decreasing the absorption of glucose from food. This helps to reduce blood sugar levels and manage type 2 diabetes.

It is typically taken once a day, with or without food, and is often used in combination with a proper diet and exercise program as part of a comprehensive treatment plan. It should not be used type 1 diabetes, a recent history of pancreatitis or kidney problems, and that you are not pregnant or breastfeeding.

Uses and Dosage

Januvia is available in the form of a tablet that you take by mouth exactly as directed by your doctor, and it is usually taken once daily. You should swallow the Januvia tablet whole with a glass of water and should not cut, chew, or crush it. It can be taken with or without food, depending on your doctor's instructions.

The recommended dosage of Sitagliptin Phosphate is 100mg once daily. However, dosage adjustment may be necessary for patients with renal impairment. It is advised to consult a healthcare professional for personalized dosage instructions based on individual medical conditions and responses to treatment.

Side Effects

Common Side Effects of Januvia (Sitagliptin Phosphate):

  • Constipation
  • Diarrhea
  • Headache
  • Nausea
  • Stomach discomfort
  • Stuffy nose

Serious Side Effects of Januvia (Sitagliptin Phosphate)

  • Changes in urine output
  • High blood sugar
  • Joint pain
  • Loss of appetite
  • Low blood sugar
  • Persistent nausea and vomiting
  • Severe abdominal pain
  • Shortness of breath
  • Swelling of the ankles and feet
  • Unusual or sudden weight gain
  • Unusual skin blisters
  • Unusual tiredness

Allergic Reactions

  • Here are the common signs of an allergy:
    • Hives
    • Itching
    • Rashes
    • Swelling of the face and neck
  • With a severe allergy, you may also experience:
    • Severe dizziness
    • Trouble breathing
    • Wheezing

Form and Strength

Januvia (Sitagliptin Phosphate) is available in the following forms and strengths:

Januvia: Film-Coated Tablet

  • 25 mg
  • 50 mg
  • 100 mg

Sitagliptin Phosphate: Tablet

  • 25 mg
  • 50 mg
  • 100 mg


  • To minimize the risk of a serious allergic reaction, do not take JANUVIA if you are allergic to any of its components, including sitagliptin. If you experience any symptoms of a serious allergic reaction, stop taking JANUVIA and get emergency medical help immediately or call your doctor without delay.
  • To use JANUVIA safely, inform your doctor or pharmacist about your medical history, including any history of kidney disease, heart failure, pancreatitis, and gallstones.
  • To ensure your safety while taking Sitagliptin Phosphate, avoid driving, operating machinery, or engaging in any activities that require alertness or clear vision if you experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels, until you are certain that you can perform such activities safely.
  • Taking Sitagliptin Phosphate while consuming alcohol increases the risk of developing low blood sugar, and therefore, limit alcohol consumption while taking the medication.
  • During pregnancy, use JANUVIA only if necessary because pregnancy can cause or exacerbate diabetes. Patients should discuss their blood sugar management plan with their doctor, and their diabetes treatment may need to be adjusted during pregnancy.

Frequently Asked Questions (FAQ)

Can Januvia cause weight loss?

Some studies suggest that Januvia may lead to modest weight loss in people with type 2 diabetes, but weight loss is not a guaranteed outcome.

Is Januvia safe for people with kidney problems?

If you have kidney problems, it is important to talk to your healthcare provider before taking Januvia. Your dosage may need to be adjusted, or an alternate medication may be recommended.

What should I do if I experience side effects from Januvia?

If you experience side effects from Januvia, speak with your healthcare provider. They may be able to adjust your dosage or recommend an alternate medication. If symptoms are severe, seek emergency medical attention.

How long does it take for Januvia to lower blood sugar?

This medication may start to lower blood sugar within one to two weeks of use. Full beneficial effects are typically achieved after a few months of taking Januvia.


It's important to purchase Januvia from verified Canadian pharmacy.

Additional information

Generic name:

Sitagliptin Malate, Sitagliptin Phosphate, Sitagliptin phosphate


Film Coated Tablet, Tablet


25mg, 50mg, 100mg

Quantities Available:

28, 84, 100