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Evista (Raloxifene) is a drug indicated to treat osteoporosis in postmenopausal women, as well as reduce the risk of developing breast cancer. It belongs to a class of drugs known as selective estrogen receptor modulators (SERM). It works by blocking the effects of estrogen, which helps reduce bone loss.

Evista is used to reduce the risk of invasive breast cancer in women with osteoporosis or those who are at elevated risk for developing the disease. It does not act like estrogen in the uterus and is not linked to an increased risk of endometrial cancer. It is not a hormone and has no effect on fertility.

Uses and Dosage

Evista (raloxifene) comes in the form of a tablet which should be taken by mouth with or without food as directed by your doctor, usually once daily. It is important to take this medication regularly to get the maximum benefit from it, and to help you remember, take it at the same time each day. The tablet should be swallowed whole; do not crush or chew it, as it has a bitter taste.

The recommended dosage of Evista (raloxifene hydrochloride tablets) is one 60 mg tablet per day, which can be taken at any time of the day without regard to meals. This dosage should not be exceeded, as taking a higher dosage may increase the risk of side effects.

Side Effect

Common Side Effects of Raloxifene:

  • Flu symptoms
  • hot flashes
  • Increased sweating
  • Joint pain
  • Leg cramps
  • Swelling in your hands, feet, or ankles

Serious Side Effects of Raloxifene:

  • Swelling, tenderness, or other changes in your breasts
  • Signs of a stroke
    • Slurred speech
    • Sudden numbness
    • Vision problems
    • Weakness (especially on one side of the body)
  • Signs of a blood clot in the lung
    • Chest pain
    • Coughing up blood
    • Trouble breathing
  • Signs of a blood clot deep in the body
    • Redness in an arm or leg
    • Swelling
    • Warmth

Form and Strength

Evista (Raloxifene) is available in the following forms and strength:

Evista: Tablet

  • 60 mg

Raloxifene: Tablet

  • 60 mg


  • Active or past history of venous thromboembolism, including deep vein thrombosis, pulmonary embolism, and retinal vein thrombosis are contraindications to Evista (raloxifene). It is important to inform your doctor if you have a history of any of these conditions before taking Evista.
  • Taking Evista (raloxifene) may increase your risk of a blood clot in your leg, your lung, or your eye. You should not take this medicine if you have ever had a blood clot, as the risk of a blood clot may be greater if you have a history of blood clots.
  • Evista increases risk of stroke, which can be fatal, especially if you have coronary heart disease or risk factors such as diabetes, smoking, being overweight, high blood pressure or cholesterol, or a family history of coronary artery disease.
  • Evista is for use only in women who can no longer get pregnant. It should not be taken by women who are pregnant or breastfeeding, as it can cause harm to the baby.
  • If you need major surgery or will be on long-term bed rest, you will need to stop taking Evista (raloxifene) at least 3 days ahead of time. You may not be able to restart the medicine until you are active again, so it is important to tell any doctor or surgeon who treats you that you are taking this medicine.

Frequently Asked Questions (FAQ)

How does Evista work?

Evista works by binding to estrogen receptors in bones and tissues, mimicking some of the beneficial effects of estrogen without its adverse effects. This helps to maintain bone strength and reduce the risk of invasive breast cancer.

What is the recommended dosage of Evista?

The recommended dosage for Evista is one 60 mg tablet daily, which may be taken at any time of day without regard to meals.

Is Evista safe for long-term use?

Evista has been approved by the FDA (Food and Drug Administration) for long-term use and is considered safe for postmenopausal women at increased risk of developing breast cancer. However, as with any medication, long-term use of Evista should be discussed with your doctor to ensure it is appropriate for your particular situation.


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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Evista (Raloxifene). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Evista (Raloxifene).