Actonel (Risedronate)

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Actonel Brand
Dosage Quantity & Price
Risedronate (Generic alternate to Actonel) Generic
Dosage Quantity & Price
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Table of contents:

Actonel is a medication used to prevent and treat certain types of bone loss or osteoporosis in adults. Actonel contains the active drug risedronate and is also used to increase bone mass in men with osteoporosis. Risedronate belongs to a class of medications called bisphosphonates. It works by slowing down bone loss and reducing the risk of broken bones and fractures.

Risedronate can help improve bone mineral density (BMD) and lower the risk of bone fractures. It helps to reduce the risk of fractures by increasing bone mass density, making bones stronger and less likely to break. It works by slowing down the breakdown of bone tissue, allowing the body to form new bone tissue more quickly.

Uses and Dosage

When taking risedronate (Actonel) tablets orally, follow the instructions provided by your doctor, typically taking it once a month after getting up for the day and before any consumption of food, beverage, or medication, while avoiding taking it at bedtime or while still in bed.

To avoid stomach and esophagus irritation, swallow the tablet whole with a full glass of plain water (6 to 8 ounces or 180 to 240 milliliters), not with any other beverage, and remain fully upright (sitting, standing, or walking) for at least 30 minutes before lying down or consuming any other food or medication. Contact your healthcare provider immediately if you have trouble swallowing, pain when swallowing, chest pain, or worsening heartburn while taking risedronate.

Risedronate (Actonel) has different dosing options depending on the condition being treated.

  • For postmenopausal osteoporosis, the dosing options include taking 5 mg by mouth once a day, 35 mg once a week, 75 mg over 2 consecutive days each month, or 150 mg once a month.
  • For osteoporosis in men, the typical dose is 35 mg by mouth once a week.
  • For osteoporosis due to long-term corticosteroid use, the typical dose is 5 mg by mouth once daily.
  • For patients with Paget's disease, the usual dose is 30 mg by mouth once daily for 2 months.

Side Effect

Common Side Effects of Actonel (Risedronate):

  • Abdominal pain
  • Back pain
  • Diarrhea
  • Flu-like symptoms
  • Heartburn
  • Pain in joints, bones, or muscles

Serious Side Effects of Actonel (Risedronate):

  • Arm or leg weakness
  • Bone fractures
  • Bone pain
  • Chest pain
  • Coughing up blood
  • Depression
  • Dizziness
  • Eye pain, redness, or swelling
  • Loose teeth or exposed bone in the mouth
  • Muscle pain
  • Neck pain
  • Numbness or heaviness in the jaw
  • Poor gum health
  • Dry mouth
  • Infections, swelling, pain, or discharge in the mouth
  • Runny nose
  • Sinus infection
  • Sore throat
  • Swelling of the arms or legs
  • Tingling or numbness
  • Tongue pain
  • Trouble sleeping

Form and Strength

Actonel (Risedronate) is available in the following forms and strength:

Actonel: Tablet

  • 5 mg
  • 30 mg
  • 35 mg
  • 75 mg
  • 150 mg

Risedronate: Tablet

  • 5 mg
  • 30 mg
  • 35 mg
  • 150 mg


  • Caution should be used when giving Actonel to patients at risk of developing certain conditions such as hypocalcemia or vitamin D deficiency. It is important to discuss any concerns or questions about Actonel with a healthcare provider before taking this medication.
  • To reduce the risk of stomach and esophagus irritation, including heartburn, pain, and ulcers, it is important to follow the prescribed directions for taking risedronate (Actonel) or Atelvia, such as drinking a full glass of plain water while standing or sitting upright and avoiding lying down for at least 30 minutes.
  • Any difficulty swallowing, new pain with swallowing, chest pain, or worsening heartburn should prompt an immediate discontinuation of risedronate (Actonel) and consultation with a healthcare professional.
  • Actonel should be avoided if one is experiencing esophageal problems or has low levels of calcium in the blood.
  • Do not take Actonel if you cannot sit upright or stand for at least 30 minutes after taking the medicine.
  • If one experiences chest pain, new or worsening heartburn, or pain during swallowing, they should discontinue the use of Actonel and contact a healthcare professional immediately as risedronate may potentially cause severe issues in the stomach or esophagus.

Frequently Asked Questions (FAQ)

What should I tell my healthcare provider before taking Actonel?

Before taking Actonel, you should tell your healthcare provider about all medical conditions you have and all medications you are taking, including supplements.

Can Actonel interact with other medications?

Yes, Actonel may interact with other medications, so it is important to tell your healthcare provider about all medications you are taking.

Are there any serious potential complications of Actonel?

Yes, in rare cases, Actonel may cause serious complications such as osteonecrosis of the jaw (ONJ) and severe suppression of bone turnover.

Can Actonel be taken with food or drink?

Take Actonel on an empty stomach, at least 30 minutes before eating or drinking anything other than water.

How long will I need to take Actonel?

The duration of Actonel treatment will depend on your individual condition and the recommendations of your healthcare provider.

What should I do if I miss a dose of Actonel?

If you miss a dose of Actonel, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your regular dose.


It's important to purchase Actonel from verified Canadian pharmacy.

Additional information

Generic name:





5mg, 30mg, 35mg, 75mg, 150mg

Quantities Available:

1, 3, 4, 6, 12, 28, 30, 60, 84, 90