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Reclast generically known as zoledronic acid is used to treat and prevent osteoporosis in postmenopausal women, as well as to treat Paget's disease of bone and bone metastases. Zoledronic acid belongs to a class of drugs known as bisphosphonates. It works by inhibiting the activity of cells that break down bone tissue, reducing pain and increasing overall bone density.
Reclast is a bisphosphonate medication, which can help strengthen bones by slowing the breakdown of bone and decreasing the release of calcium from bones into circulation. It helps to reduce the risk of fractures by increasing bone density and strength. It is given as an intravenous infusion administered by a healthcare provider.
Uses and Dosage
Zoledronic acid comes as a solution (liquid) to be injected into a vein over at least 15 minutes. It is usually administered by a healthcare provider in a hospital, clinic, or doctor's office. Eat and drink normally on the day of treatment. Drink at least 2 glasses of fluid before treatment unless otherwise directed by your doctor.
If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.
The dosing regimen for zoledronic acid injection depends on the condition being treated.
- For high blood levels of calcium caused by cancer, a single dose is typically given. A second dose may be given at least 7 days after the first dose if blood calcium levels do not drop to normal or do not remain at normal levels.
- For bone damage caused by multiple myeloma or cancer that has spread to the bones, zoledronic acid injection is typically given once every 3 to 4 weeks.
- For osteoporosis in women who have undergone menopause, or in men, or to treat or prevent osteoporosis in people who are taking glucocorticoids, zoledronic acid injection is usually given once a year.
- For the prevention of osteoporosis in women who have undergone menopause, zoledronic acid injection is typically given once every 2 years.
- When zoledronic acid is used to treat Paget's disease of bone, it is usually given as a single dose. Additional doses may be given after some time has passed.
Common Side Effects of Reclast (Zoledronic Acid IV Solution):
- Arm or leg pain
- Back pain
- Bone pain
- Flu-like symptoms
- Higher blood pressure
- Joint pain
- Muscle pain
- Shoulder pain
Serious Side Effects of Reclast (Zoledronic Acid IV Solution):
- Anemia (low red blood cell count)
- Arm or leg swelling
- Body weakness
- Feeling unsteady (vertigo)
- Muscle spasms
- Neck pain
- Stomach pain
Form and Strength
Reclast (Zoledronic Acid IV Solution) is available in the following forms and strength:
- 5mg/ 100 ml
- Patients with kidney disease should use Reclast (zoledronic acid) with caution, as the medication has the potential to cause kidney problems. Discuss kidney health with a healthcare provider before beginning treatment with Reclast to evaluate any potential risk.
- Reclast can cause low levels of calcium in the blood, so calcium and vitamin D supplements may be needed in patients who are at risk of developing hypocalcemia.
- Some patients taking zoledronic acid may experience severe bone, joint, or muscle pain after taking the medication. This can happen as soon as one day after taking the medication and can last for several weeks.
- There have been rare reports of osteonecrosis of the jaw (bone death) in patients taking bisphosphonates, including Reclast.
- Do not use Reclast during pregnancy, as it may cause harm to the developing fetus. Additionally, the medication's potential impact on breast milk has not been established, so it should be used with caution in nursing mothers.
- Pregnant woman should not use zoledronic acid as it may pose a risk to the developing fetus. Additionally, it is unclear whether Reclast can pass into breast milk, so nursing mothers should use the medication with caution.
- Reclast should not be used in patients with dental problems or undergoing dental procedures, as it may increase the risk of jawbone problems.
Frequently Asked Questions (FAQ)
Who should not use Reclast?
Reclast is not recommended for use in patients who are pregnant or have kidney problems. Additionally, discuss any pre-existing dental problems with a healthcare provider before using Reclast.
Can Reclast be used in combination with other medications?
Reclast can interact with certain medications or supplements, so it is important to inform a healthcare provider of any medications or supplements being taken prior to treatment.
Can Reclast be used in men?
Yes, Reclast can be used to treat osteoporosis in men. The medication has been shown to reduce the risk of fractures in men with osteoporosis, as well as in men receiving androgen deprivation therapy for prostate cancer.
How long does Reclast stay in the body?
Reclast is eliminated from the body slowly, with an average half-life of about 146 hours. After a single infusion, it can take several months for the medication to be fully eliminated from the body.
It's important to purchase Reclast from verified Canadian pharmacy.