Emend Tri Pack (Aprepitant)

Indications

Emend Tri-Pack (Aprepitant) is a medication used in combination with other medicines to prevent nausea and vomiting caused by cancer treatment (chemotherapy). It helps to prevent acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic chemotherapy.

Emend Tri Pack contains Aprepitant as active ingiredent. Aprepitant is in a class of medications called antiemetics. It works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.

Use and Dosage

Emend Tri Pack comes in the form of capsules to take orally by mouth with or without food as directed by your doctor. Swallow the capsules whole without crushing and chewing it. Emend Tri Pack should not be taken for longer than 3 consecutive days during each cycle of chemotherapy.

The dosage is based on your medical condition, age, and response to treatment. In children, the dosage is also based on weight. Follow your doctor's instructions for when to take each dose, how long to keep taking it, and the strength (number of milligrams) of each dose.

Take the first dose as directed by your doctor, usually 1 hour before the start of chemotherapy. For the next 2 days, continue to take a dose once daily 1 hour before the start of treatment if you are getting chemotherapy that day. If you are not getting any chemotherapy, then take the dose once daily in the morning.

The Tri-Pack contains 2 capsules of EMEND 80 mg and 1 capsule of EMEND 125 mg. The recommended dose for the 3-day oral regimen is 125 mg orally 1 hour before chemotherapy on day 1, and 80 mg orally once daily on days 2 and 3.

If you have not discussed this with your doctor or are not sure why you are taking Emend Tri Pack capsules, speak to your doctor. Do not stop taking Emend Tri Pack capsules without consulting your doctor.

Side Effects

Common Side Effects of Emend Tri Pack (Aprepitant):

• Constipation
• Diarrhea
• Dizziness
• Fever
• Gas
• Hair loss
• Headache
• Heartburn
• Hiccups
• Loss of appetite
• Nausea
• Stomach pain
• Tiredness
• Weakness

Serious Side Effects of Emend Tri Pack (Aprepitant):

• Anxiousness
• Difficulty breathing or swallowing
• Fever
• Hives
• Increased sweating
• Itching
• Low blood pressure
• Painful or burning urination
• Rash
• Red or itchy eyes with discharge
• Ringing in the ears
• Severe rash, itching, or swelling of the hands and feet
• Signs of a severe skin reaction such as blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort
• Signs of infection (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness
• Skin peeling or blisters
• Symptoms of a severe allergic reaction (difficulty breathing; hives; swelling of the face, eyes, lips, tongue, or throat)

Forms and Strength

Emend Tri Pack (Aprepitant) is available in the following forms and strength:

Emend Tri Pack: Capsule

• 125/80mg

Cautions

• Emend Tri Pack capsules may interact with other medicines, herbs, non-prescription drugs, or dietary supplements. Inform your healthcare provider of all the medications and supplements you take.
• Emend Tri-Pack may cause dizziness or fatigue, which can impair your ability to operate machinery or drive a car.
• Emend Tri-Pack may cause liver problems in some people. Your healthcare provider may monitor your liver function while you take Emend Tri Pack capsules.
• Emend Tri-Pack should not be used during pregnancy unless clearly necessary, as it may harm the fetus.
• Emend Tri-Pack should be used with caution in people with kidney problems. Your healthcare provider may adjust the dose if you have reduced kidney function.
• Emend Tri-Pack may cause allergic reactions in some people. If you experience symptoms of an allergic reaction, such as rash, hives, or difficulty breathing, seek medical attention immediately.
• Emend Tri-Pack may interact with certain medications used to regulate heart rhythms, such as quinidine, as well as certain medications used to reduce pain or inflammation, such as dexamethasone. Your healthcare provider will need to monitor you closely if you take these medications in combination with Emend Tri-Pack.
• Emend Tri-Pack may increase blood levels of certain medications, such as warfarin, which can increase the risk of bleeding. Your healthcare provider may need to adjust your dose of these medications if you take them along with Emend Tri-Pack.
• Emend Tri-Pack should not be used in children under 12 years old, as its safety and effectiveness in this age group have not been established.
• Emend Tri-Pack may cause some common side effects, such as constipation, diarrhea, or loss of appetite. If these side effects persist or become severe, speak with your healthcare provider.

Frequently Asked Questions (FAQ)

Can Emend Tri-Pack be used in children?

Emend Tri-Pack should not be used in children under 12 years old, as its safety and effectiveness in this age group have not been established.

Does Emend Tri-Pack require a prescription?

Yes, Emend Tri-Pack is a prescription medication and requires a healthcare provider's prescription.

What should I do if I miss a dose of Emend Tri-Pack?

If you miss a dose of Emend Tri-Pack, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time.

Can Emend Tri-Pack be taken with food or on an empty stomach?

Emend Tri-Pack should be taken without food but can be taken with or without water.

How should Emend Tri-Pack be stored?

Emend Tri-Pack should be stored at room temperature, away from light and moisture.

Resources

• https://medlineplus.gov/druginfo/meds/a604003.html
• https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=db16d6b9-3b89-431d-97f9-9b4a8300e913
• https://discountdrugsfromcanada.com/emend-tri-pack-aprepitant.html
• https://www.medbroadcast.com/drug/getdrug/emend
• https://www.webmd.com/drugs/2/drug-75035/emend-oral/details
• https://www.ema.europa.eu/en/documents/product-information/emend-epar-product-information_en.pdf