Edarbyclor contains azilsartan medoxomil and chlorthalidone and is taken by mouth to help lower high blood pressure. It is usually taken once daily, with or without food.
Take Edarbyclor exactly as prescribed by your healthcare provider. Try to take it at about the same time every day so it becomes part of your regular routine.
Recommended Starting Dose
The usual starting dose is 40 mg/12.5 mg once daily.
This means each tablet contains:
- 40 mg of azilsartan medoxomil
- 12.5 mg of chlorthalidone
Your healthcare provider may choose this dose when one blood pressure medicine is not enough or when you are likely to need more than one medicine to reach your blood pressure goal.
Increasing the Dose
Most of the blood pressure-lowering effect becomes noticeable within about 1 to 2 weeks.
If your blood pressure is still higher than your target, your healthcare provider may increase the dose after 2 to 4 weeks to 40 mg/25 mg once daily. This is the maximum recommended dose.
Do not increase the dose on your own, even if your home blood pressure readings remain high.
Can Edarbyclor Be Taken With Food?
Yes. Edarbyclor can be taken with or without food.
Choose a routine that is easy for you to follow consistently. Taking it at the same time each day may make it easier to remember.
When is the Best Time to Take Edarbyclor?
Because chlorthalidone is a diuretic, or water pill, it can increase urination.
Many people find it more convenient to take Edarbyclor earlier in the day so they are less likely to wake up at night to use the bathroom. However, the official prescribing information does not require a specific time of day, so follow your healthcare provider’s instructions.
Why Does Edarbyclor Increase Urination?
Chlorthalidone helps the kidneys remove extra sodium and water from the body.
You may notice more frequent urination after taking your medication, especially when you first start treatment. This effect helps reduce fluid volume and contributes to lowering blood pressure.
Take Edarbyclor Every Day
Continue taking Edarbyclor even if you feel well.
High blood pressure often causes no noticeable symptoms, so you may not feel different even when the medication is working.
Do not stop taking Edarbyclor without speaking with your healthcare provider because your blood pressure may rise again.
How Will You Know if the Medication is Working?
Regular blood pressure checks are the best way to tell whether Edarbyclor is working.
Your healthcare provider may ask you to monitor your blood pressure at home. Keep a record of your readings and share them during follow-up appointments.
Do not take an extra tablet if one reading is higher than usual.
If You Are Dehydrated
Edarbyclor can cause blood pressure to drop too low in people who have lost a significant amount of fluid or salt.
Tell your healthcare provider if you have had severe vomiting, diarrhea, heavy sweating, or dehydration, particularly before starting treatment. The prescribing information recommends correcting significant fluid depletion before Edarbyclor is started.
Blood Tests During Treatment
Edarbyclor can affect kidney function and electrolyte levels, including sodium and potassium.
Your healthcare provider may order blood tests during treatment to check that your kidneys are working properly and your electrolyte levels remain within a safe range.
What If You Miss a Dose?
If you forget to take Edarbyclor, the current patient instructions say to take the missed dose later that same day when you remember.
If you do not remember until the next day, skip the missed dose and continue your normal schedule. Do not double your dose the following day.
Can Edarbyclor Be Taken With Other Blood Pressure Medicines?
Yes. Edarbyclor may be used with other blood pressure medicines when additional control is needed.
Your healthcare provider may monitor you more closely because combining blood pressure medicines can sometimes cause dizziness or blood pressure that becomes too low.
What If You Feel Dizzy?
Dizziness can occur, particularly when you first begin treatment or if your blood pressure becomes too low.
Stand up slowly after sitting or lying down. Contact your healthcare provider if you have repeated dizziness, weakness, or fainting.
Pregnancy Warning
Edarbyclor can cause serious harm to a developing baby because it contains azilsartan, an ARB.
If you become pregnant while taking Edarbyclor, contact your healthcare provider promptly so your blood pressure treatment can be changed.
How Should Edarbyclor Be Stored?
Store Edarbyclor at room temperature and keep it in its original container, tightly closed and protected from light and moisture. The prescribing information specifically advises against repackaging the tablets.
Important Reminder
The usual starting dose of Edarbyclor is 40 mg/12.5 mg once daily. If additional blood pressure control is needed, your healthcare provider may increase the dose after 2 to 4 weeks to 40 mg/25 mg once daily, which is the maximum recommended dose.
Take Edarbyclor consistently, continue checking your blood pressure as recommended, and do not change your dose without speaking with your healthcare provider.
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