Indications
Edarbyclor is a prescription medication used to treat high blood pressure (hypertension). It is a combination of two medications, azilsartan medoxomil, an angiotensin II receptor antagonist, and chlorthalidone, a diuretic. Edarbyclor works by relaxing blood vessels, helping to lower blood pressure, and removing excess water and salt from the body.
Azilsartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so blood can flow more easily. Chlorthalidone is a "water pill" or diuretic. It causes your body to get rid of extra salt and water by making more urine.
Uses and Dosage
Edarbyclor comes in the form of a tablet and should be taken orally with or without food as directed by your healthcare provider, typically once daily. Avoid taking Edarbyclor too close to bedtime as it may cause the need to wake up to urinate. Take the tablet at least 4 hours before going to bed.
The dosage of Edarbyclor will be determined by your healthcare provider based on your medical condition and response to treatment. To get the most benefit from the medication, take it regularly at the same time each day. Even if you feel well, keep taking Edarbyclor as most people with high blood pressure do not experience any symptoms. It may take several weeks before you experience the full benefit of the medication.
The usual dosing for Edarbyclor (azilsartan/chlorthalidone) is 40 mg/12.5 mg taken orally once daily. After 2 to 4 weeks, your healthcare provider may increase your dose to a maximum of 40 mg/25 mg (azilsartan/chlorthalidone).
Side Effect
Common Side Effects of Edarbyclor (Azilsartan Medoxomil/Chlorthalidone):
- Dizziness
- Nausea
- Vomiting
- Fatigue
- Headache
- Diarrhea
Serious Side Effects of Edarbyclor (Azilsartan Medoxomil/Chlorthalidone):
- Blurred vision
- Confusion
- Convulsions
- Decreased urine
- Faintness
- Lightheadedness
- Dry mouth
- Fainting
- Increased thirst
- Irregular heartbeat
- Loss of appetite
- Muscle pain or cramps
- Numbness or tingling in the hands, feet, or lips
- Shortness of breath
- Sweating
- Unusual tiredness or weakness
Form and Strength
Edarbyclor (Azilsartan Medoxomil/Chlorthalidone) is available in the following forms and strength:
Edarbyclor: Tablet
- 40/25 mg
- 40/12.5 mg
Azilsartan Medoxomil/Chlorthalidone: Tablet
- 40/25 mg
Caution
- Edarbyclor can cause serious side effects such as hyperkalemia (high potassium levels in the blood), low blood pressure, and problems with the kidneys and liver.
- Inform your healthcare provider about any medical conditions, medications, or supplements that you are currently taking before starting Edarbyclor.
- Edarbyclor should not be taken during pregnancy, as it can harm the fetus. Women of childbearing age should use effective birth control while taking the medication.
- Monitor blood pressure and electrolyte levels regularly while taking Edarbyclor.
- Edarbyclor may interact with other medications and supplements, inform your healthcare provider about all medications that you are taking before starting Edarbyclor.
- Edarbyclor may cause dizziness or lightheadedness, so caution should be taken while driving or operating machinery.
- Edarbyclor may cause a decrease in urine output, stay hydrated and inform your healthcare provider if you experience any changes in urine output while taking the medication.
- Edarbyclor should not be stopped abruptly, as it can cause a rapid increase in blood pressure. Discuss any concerns or questions about Edarbyclor with your healthcare provider before starting the medication.
- If you feel faint or dizzy, lie down and call your doctor right away. If you pass out (faint), have someone call your doctor or get medical help. Stop taking Edarbyclor.
Frequently Asked Questions (FAQ)
Can I take Edarbyclor if I am pregnant or breastfeeding?
No, Edarbyclor should not be taken during pregnancy, as it can harm the fetus. Women of childbearing age should use effective birth control while taking the medication.
Can I drink alcohol while taking Edarbyclor?
Do not drink alcohol while taking Edarbyclor, as it can increase the risk of certain side effects, such as dizziness and low blood pressure.
Can children use Edarbyclor (azilsartan / chlorthalidone)?
No, Edarbyclor (azilsartan / chlorthalidone) is only approved for use in adults 18 years of age and older.
How long does Edarbyclor stay in your system?
Azilsartan medoxomil, when administered alone or in combination with chlorthalidone, is eliminated from plasma with an elimination half-life of 11-13 hours. Azilsartan is metabolized to two primary metabolites.
Resources
- https://www.empr.com/drug/edarbyclor/
- https://www.drugs.com/edarbyclor.html
- https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e60f795b-fce3-4361-aa03-f143451689d1
- https://www.rxlist.com/edarbyclor-drug.htm#side_effects
- https://www.goodrx.com/edarbyclor/what-is
- https://www.webmd.com/drugs/2/drug-159144/edarbyclor-oral/details
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/202331lbl.pdf
REVIEWS