Atacand HCT (Candesartan/HCTZ)

Indications

Atacand HCT is a prescription medication that is used to treat high blood pressure (hypertension) and swelling (edema). It is a combination of two active ingredients: candesartan cilexetil and hydrochlorothiazide.

Candesartan cilexetil is an angiotensin II receptor antagonist, which means it helps to relax blood vessels and improve blood flow by blocking the action of a hormone called angiotensin II. Angiotensin II is a natural substance in the body that causes blood vessels to narrow and can raise blood pressure.

On the other hand, hydrochlorothiazide is a thiazide diuretic that helps the body get rid of excess water and salt through urine. By combining these two medications, Atacand HCT can help lower blood pressure and decrease fluid accumulation in the body, which can help treat conditions such as hypertension and edema.

Use and Dosage

Atacand HCT (Candesartan/HCTZ) is available in tablet form and should be taken orally, with or without food, as directed by your doctor. Typically, it is taken once daily. Avoid taking Atacand HCT within 4 hours of bedtime to avoid the need to urinate during the night.

The recommended dosage of Atacand HCT (candesartan/hydrochlorothiazide) depends on the individual's medical condition and response to treatment. Generally, the usual recommended starting dose of candesartan cilexetil is 16 mg once daily, and the dosage range for hydrochlorothiazide is between 12.5 mg to 25 mg once daily. The optimum therapeutic effect is expected within 4 weeks.

To ensure the maximum benefit from the medication, take it at the same time each day and continue using it even if you feel well. It may take up to 4 weeks to experience the full benefit of this medication. If you have any questions about your dosing schedule, consult your doctor or pharmacist.

Side Effects

Common Side Effects of Atacand HCT (Candesartan/HCTZ):

• Back pain
• Cold or flu symptoms
• Dizziness

Serious Side Effects of Atacand HCT (Candesartan/HCTZ):

• Confusion
• Constipation
• Dark colored urine
• Difficulty breathing
• Easy bruising
• Eye pain
• Feeling unsteady
• Fever
• Fluttering in your chest
• Hives
• Increased thirst or urination
• Irregular heartbeats
• Leg cramps
• Lightheadedness
• Limp feeling
• Little or no urinating
• Loss of coordination
• Muscle pain
• Muscle weakness
• Numbness or tingling
• Swelling of your face lips tongue or throat
• Tenderness
• Unusual bleeding
• Unusual tiredness
• Vision problems
• Vomiting
• Weakness
• Yellowing of the skin or eyes (jaundice)

Forms and Strength

Atacand HCT (Candesartan/HCTZ) is available in the following forms and strength:

Atacand HCT: Tablet

• 16/12.5mg
• 32.5/12.5mg

Candesartan/HCTZ: Tablet

• 16/12.5mg

Cautions

• Pregnancy: Atacand HCT can cause harm to an unborn baby and should not be used during pregnancy.
• Breastfeeding: Atacand HCT may pass into breast milk and may harm a breastfeeding infant. Talk to your doctor before taking Atacand HCT if you are breastfeeding.
• Liver or kidney disease: Atacand HCT can worsen liver or kidney problems, talk to your doctor if you have a history of these conditions.
• Electrolyte imbalances: Hydrochlorothiazide, one of the components of Atacand HCT, can cause levels of electrolytes such as potassium, sodium, and magnesium to become imbalanced. Your doctor may monitor your electrolyte levels during treatment.
• Low blood pressure: Atacand HCT can cause a drop in blood pressure, especially when standing up from a sitting or lying down position. This can cause dizziness, fainting or falls.
• Allergies: Some people may be allergic to the components of Atacand HCT and should avoid it.
• Diabetes: Atacand HCT may affect blood sugar levels and may require adjusting doses of medications used to treat diabetes.
• Gout: Hydrochlorothiazide, one of the components of Atacand HCT, can increase the risk of gout, so it is important to talk to your doctor if you have a history of gout.
• Surgery or anesthesia: Atacand HCT may increase the risk of low blood pressure during surgery or anesthesia, so it is important to inform your healthcare provider of your use of this medication prior to any surgeries.
• Skin reactions: Rarely, Atacand HCT may cause serious skin reactions such as rash and blisters. Seek medical attention immediately if you experience any skin reactions while taking this medication.

Frequently Asked Questions (FAQ)

Is Atacand HCT safe to take during pregnancy?

Atacand HCT is not recommended during pregnancy due to the risk of fetal harm. Speak to your healthcare provider before taking any medication during pregnancy.

How long does it take for Atacand HCT to start working?

It may take several weeks of regular use for Atacand HCT to fully control blood pressure. Taking the medication as directed by your healthcare provider, even if you feel better.

Can Atacand HCT cause dehydration?

Yes, hydrochlorothiazide, one of the components of Atacand HCT, is a diuretic and can cause dehydration if too much fluid is lost too quickly.

Resources

• https://www.rxlist.com/atacand-hct-drug.htm
• https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021093s021lbl.pdf
• https://www.webmd.com/drugs/2/drug-19957/atacand-hct-oral/details
• https://www.goodrx.com/candesartan-hctz/what-is
• https://www.drugs.com/mtm/atacand-hct.html