Buscopan Ampules (Hyoscine)

Indications

Buscopan is an injectable medication used to relieve cramps in the muscles of various organs, including the stomach, gut, bladder, and tubes leading to the outside of the body. It contains hyoscine butylbromide as its active ingredient and is available in 20mg/1mL injection ampoules.

Buscopan can be used to treat acute spasm, such as in renal or biliary colic, in radiology for differential diagnosis of obstruction, and to reduce spasm in abdominal pain.

Use and Dosage

Buscopan ampoules are typically administered by medical professionals and should not be used long-term daily. They can be administered through a slow injection into a vein or a muscle. If necessary, Buscopan ampoules can be mixed with other solutions.

You will usually be given one ampoule, but you may be given a further ampoule after half an hour if required. If you are being given Buscopan ampoules as part of an endoscopy your dose may need to be given more often. You should not be given more than 5 ampoules in any 24-hour period. Buscopan ampoules are not recommended for children.

Side Effects

Common Side Effects of Buscopan Ampules (Hyoscine):

• A skin condition called dyshidrosis (small blisters on the hands and feet)
• Abnormal sweating
• Drop in blood pressure
• Fast heart rate
• Itching
• Rash
• Redness of the skin
• Reduced sweating

Serious Side Effects of Buscopan Ampules (Hyoscine):

• Agitation
• Allergic reactions (such as skin rashes or swelling of the face and difficulty in breathing)
• Coma
• Confusion
• Dizziness
• Hallucinations (seeing, feeling, or hearing things that are not there)
• Sudden life-threatening allergic reactions (anaphylaxis with episodes of shortness of breath and shock)
• Unusual muscle tone causing distortion of the body (dystonia)

Forms and Strength

Buscopan Ampules (Hyoscine) is available in the following forms and strength:

Buscopan Ampules: Ampules

• 20mg/mL

Cautions

You should not receive this medicine if any of the below apply to you. If you are not sure, talk to your doctor or pharmacist before taking this medicine.

• You are allergic (hypersensitive) to hyoscine butylbromide or any of the other ingredients.
• You have glaucoma (an eye problem).
• You have megacolon (a very enlarged bowel).
• You have myasthenia gravis (an exceedingly rare muscle weakness problem).
• You have an extremely fast heart rate.
• You have difficulty or pain passing water (urine) such as men with prostate problems.
• You have gut blockage problems or a totally inactive gut.
• You are pregnant, likely to get pregnant or are breast-feeding.

Frequently Asked Questions (FAQ)

How many mg of pethidine are in a stock ampoule?

A stock ampoule of pethidine contains 100 mg in 2 mL.

Can Buscopan Ampules be given to pregnant women?

Buscopan Ampules should only be given to pregnant women under medical supervision and when the potential benefits outweigh the potential risks.

How should Buscopan Ampules be stored?

Buscopan Ampules should be stored at room temperature, away from heat and direct light. They should also be kept out of the reach of children.

Can Buscopan Ampules be used for menstrual cramps?

Buscopan Ampules may be used off-label for the relief of menstrual cramps, though this should only be done under medical supervision.

Resources

• https://www.drugs.com/uk/buscopan-ampoules-20mg-ml-leaflet.html
• https://www.news-medical.net/drugs/Buscopan-Injection.aspx
• https://www.tga.gov.au/resources/artg/17916
• https://k2.kaysmedical.com/productdetails/buscopan-ampoules-hyoscine-injection--20mg-10-pom/BUS23J
• https://www.hpra.ie/img/uploaded/swedocuments/1c63e277-2a1a-4d5f-9d64-e04a7455c401.pdf