Indications
Asacol (active ingredient: mesalamine) is a prescription medication indicated for the following:
- Ulcerative Colitis: Asacol is used to treat and manage mild to moderate ulcerative colitis by reducing inflammation in the colon and rectum.
- Maintenance of Remission: It is also indicated for the maintenance of remission of ulcerative colitis, helping to prevent flare-ups of the condition.
Asacol belongs to a class of drugs known as aminosalicylates, which work by inhibiting the production of certain chemicals in the lining of the colon that cause inflammation.
Uses and Dosage
Asacol (mesalamine) comes in tablet form and is taken by mouth with or without food as directed by your doctor, usually three times daily. Swallow the tablet whole without crushing, chewing, or breaking it, as this can prevent the drug from being properly released into the colon. Drink plenty of fluids during treatment with Asacol, unless otherwise directed by your doctor, to help prevent kidney stones.
To get the most benefit from Asacol, use the medication regularly and take it at the same time each day. The dosage and duration of treatment may vary depending on the severity of the condition and the patient's response to the medication.
For adults, the recommended dosage of Asacol is typically 800 mg (two 400 mg tablets) three times daily, for a total daily dosage of 2.4 grams, for 6 to 8 weeks. However, the dosage can go up to 1.6 grams (four 400 mg tablets) three times daily, depending on individual medical needs and response to the medication.
Side effect
Common Side Effects of Asacol (Mesalamine):
- Abnormal liver function tests
- Diarrhea
- Gas
- Headache
- Indigestion
- Nausea
- Rash
- Stomach pain
- Vomiting
Serious Side Effects of Asacol (Mesalamine):
- Bloody diarrhea
- Bloody or tarry stools
- Clay-colored stools
- Coughing up blood
- Dark urine
- Easy bruising or bleeding
- Feeling tired
- Fever
- Headache
- Little or no urination
- Loss of appetite
- Painful or difficult urination
- Severe stomach pain
- Shortness of breath
- Skin rash
- Stomach cramping
- Swelling in your feet or ankles
- Upper stomach pain
- Vomit that looks like coffee grounds
- Yellowing of the skin or eyes
Form and Strength
Asacol (Mesalamine) is available in the following forms and strength:
Asacol: DR Tablet
- 400 mg
Mesalamine: DR Tablet
- 400 mg
Caution
- Asacol may interact with other medications, including blood thinners, nonsteroidal anti-inflammatory drugs (NSAIDs), and immunosuppressants. Talk to a healthcare professional about all medications being taken to avoid any potential interactions.
- Allergic reactions to Asacol are rare, but they can occur. Symptoms of an allergic reaction may include hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.
- If you are allergic to mesalamine or any of the ingredients in Asacol, you should not take the medication.
- Asacol can make your skin sensitive to the sun if you have skin conditions such as atopic dermatitis and atopic eczema. Try to limit your time in the sun. You should use sunscreen and wear a hat, and clothes that cover your skin, if you have to be in the sunlight.
- Asacol may cause kidney problems or make existing kidney problems worse. Tell your doctor if you have kidney problems before taking Asacol.
- Asacol may cause liver problems or make existing liver problems worse. Your doctor may monitor your liver function while you are taking Asacol.
- Asacol may affect blood cell count or increase the risk of bleeding. Tell your doctor if you have a history of blood disorders or are taking blood thinners.
- Asacol should only be used during pregnancy if it is clearly needed. It is not known if Asacol passes into breast milk.
Frequently Asked Questions (FAQ)
How long does it take for Asacol to work?
The time it takes for Asacol to work can vary depending on the severity of the condition and the patient's response to the medication. Continue taking Asacol as directed by a healthcare professional, even if symptoms improve.
How should Asacol be stored?
Asacol should be stored at room temperature away from moisture and heat.
What should I do if I miss a dose of Asacol?
If a dose of Asacol is missed, it should be taken as soon as possible. If it is close to the time for the next scheduled dose, the missed dose should be skipped, and the regular dosing schedule resumed.
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