Indications
Agrylin is a prescription medication used to treat the symptoms of thrombocythemia or thrombocytosis, which is a blood disorder where the bone marrow produces too many platelets. Anagrelide is the active ingredient in Agrylin. Anagrelide belongs to the family of medications called platelet-reducing agents.
If your body makes too many platelets, it is hard for your blood to flow normally and it will be more likely to clot or bleed. This can cause medical problems such as heart attacks, stroke, blood clots in the lung or legs, as well as bleeding from the stomach, gums, or nose. Agrylin works by slowing down the body's ability to make platelets, which helps to reduce the risk of blood clots. It is available in capsule form, and the usual dosage is 0.5 mg taken orally twice daily.
Use and Dosage
Agrylin is typically available in capsule form for oral administration, and it is usually prescribed to be taken 2 to 4 times daily or as directed by a doctor. It can be taken with or without food and should be swallowed whole with water. Do not chew or divide the capsules.
The recommended dosage of Agrylin (anagrelide) varies based on the patient's medical condition and response to treatment. For adults, the recommended starting dosage is usually 0.5 mg four times daily or 1 mg twice daily. Children or individuals with liver problems may start out with a lower dosage. Additionally, your doctor may adjust your dosage once a week to find the best dose for you.
To ensure the full benefits of Agrylin, take it regularly and exactly as prescribed. A dosing schedule can be helpful to avoid missing a dose, and do not change the dosing or frequency of the medication without consulting your physician. Additionally, continue taking Agrylin without interruption and to avoid stopping it suddenly to avoid rebound effects.
Side Effects
Common Side Effects of Agrylin (Anagrelide):
- Abdominal pain
- Diarrhea
- Dizziness
- Gas
- Headache
- Loss of appetite
- Nausea
- Upset stomach
Serious Side Effects of Agrylin (Anagrelide):
- Changes in urine output
- Chest pain
- Confusion
- Irregular heartbeat
- Seizures
- Severe abdominal pain
- Severe dizziness
- Shortness of breath
- Unusual bruising or bleeding (bleeding gums, blood in the stool, coughing out blood)
- Vision changes
Forms and Strength
Agrylin (Anagrelide) is available in the following forms and strength:
Agrylin: Capsule
- 0.5 mg
Anagrelide: Capsule
- 0.5 mg
Cautions
- Anagrelide should be used with caution in patients with known or suspected kidney or liver disease.
- Anagrelide may cause a decrease in white blood cell count or platelet count, which can increase the risk of infection or bleeding.
- Anagrelide should not be used in pregnant or breastfeeding women unless the potential benefits outweigh the potential risks.
- Anagrelide may interact with other medications, inform your doctor of all medications being taken before starting treatment with anagrelide.
- Anagrelide may cause dizziness or lightheadedness; avoid activities that require alertness until the effects of the medication are known.
- Anagrelide may increase the risk of developing heart problems, such as heart attack or irregular heartbeat.
- Anagrelide may cause fluid retention, which can lead to swelling in the legs and other parts of the body.
- Anagrelide may affect blood sugar levels, which may be a concern for people with diabetes or those at risk for developing diabetes.
- Anagrelide may affect the function of the adrenal glands, which can affect how the body responds to stress.
Frequently Asked Questions (FAQ)
What should I do if I miss a dose of Agrylin?
If you miss a dose of Agrylin, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
How long does it take for Agrylin to work?
Agrylin varies from person to person, but it usually takes a few weeks for Agrylin to lower platelet levels.
Can Agrylin cure thrombocythemia?
Agrylin cannot cure thrombocythemia, but it can help manage the high platelet levels associated with the condition.
Is it safe to drink alcohol while taking Agrylin?
Avoid drinking alcohol while taking Agrylin, as alcohol can increase the risk of side effects such as dizziness and drowsiness.
Resources
- https://www.goodrx.com/agrylin/whatis
- https://www.drugs.com/mtm/agrylin.html
- https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cb96007499c14a73941ff0644a7ec219
- https://www.webmd.com/drugs/2/drug1038/agrylinoral/details
- https://www.rxlist.com/agrylindrug.htm
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020333s017lbl.pdf
- https://www.medbroadcast.com/drug/getdrug/agrylin
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