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Formulation: Solution
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Formulation: Solution
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Pennsaid (active ingredient: diclofenac sodium) is a prescription topical medication used to relieve pain and inflammation caused by osteoarthritis of the knee in adults.
It is applied directly to the skin over the affected knee, allowing diclofenac to work mainly in the area where the pain and inflammation are occurring.
Osteoarthritis is a common joint condition that develops when the protective cartilage covering the ends of bones gradually wears down.
When osteoarthritis affects the knee, the joint may become painful, stiff, swollen, or difficult to move.
Common symptoms may include:
Pennsaid is used to help reduce these symptoms and make everyday movement more comfortable.
Pennsaid belongs to a group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs).
Diclofenac works by blocking enzymes called cyclooxygenase enzymes, also known as COX enzymes. These enzymes help the body produce substances called prostaglandins.
Prostaglandins are involved in pain, swelling, and inflammation.
By reducing prostaglandin production in the treated area, Pennsaid can help decrease:
Pennsaid is a topical NSAID, which means it is applied directly to the skin rather than taken by mouth.
This allows diclofenac to reach the tissues around the affected knee while generally resulting in lower amounts of the medication circulating throughout the body than with oral diclofenac.
However, some diclofenac can still be absorbed into the bloodstream. For this reason, Pennsaid can still cause some of the same serious side effects associated with other NSAIDs.
Pennsaid may help make activities such as walking, standing, bending the knee, and climbing stairs less uncomfortable when pain is caused by knee osteoarthritis.
The amount of relief can vary from person to person, and it may take regular use before the full benefit is noticed.
Pennsaid helps control the symptoms of osteoarthritis, but it does not cure the condition or restore damaged cartilage.
It is usually used as part of an overall osteoarthritis treatment plan, which may also include exercise, weight management, physical therapy, or other treatments recommended by a healthcare provider.
Use Pennsaid only on the affected knee and exactly as prescribed.
Do not apply more medication or use it more often than recommended. Even though Pennsaid is applied to the skin, diclofenac is still an NSAID and can cause serious side effects in some people.
Contact your healthcare provider if your knee pain becomes worse, does not improve with treatment, or is accompanied by severe swelling, redness, or difficulty moving the joint.
Pennsaid is a topical solution applied directly to the skin over the affected knee.
Use Pennsaid exactly as prescribed by your healthcare provider. The amount and frequency depend on the strength and formulation you have.
For Pennsaid 2% topical solution, the recommended dose is generally 2 pump actuations on each painful knee twice daily.
Apply it in the morning and evening, or according to the schedule provided by your healthcare provider.
The older Pennsaid 1.5% topical solution is measured in drops.
The recommended dose for knee osteoarthritis is 40 drops on each painful knee four times daily.
Do not use the dosing instructions for one strength with another formulation. Check your prescription label to make sure you are using the correct dose.
Apply Pennsaid to clean, dry skin.
Spread the medication evenly over the entire affected knee, including the front, back, and sides of the joint.
Do not apply Pennsaid to broken, infected, swollen, or irritated skin unless your healthcare provider tells you otherwise.
Wash and dry your hands thoroughly after applying Pennsaid unless your hands are the area being treated.
Avoid touching your eyes, nose, or mouth before washing your hands.
Allow Pennsaid to dry completely before covering the knee with clothing or applying other products to the treated area.
Avoid skin-to-skin contact between the treated knee and another person until the medication has dried.
For the 1.5% formulation, avoid showering or bathing for at least 30 minutes after applying Pennsaid.
Follow the instructions provided with your specific Pennsaid formulation regarding bathing, swimming, or washing the treated area.
Use Pennsaid at approximately the same times each day.
Do not apply more medication, use it more frequently, or treat additional areas unless your healthcare provider tells you to do so.
Using more Pennsaid than prescribed may increase the amount of diclofenac absorbed into your body and may increase the risk of side effects.
Pennsaid (Diclofenac sodium) is available in the following forms and strengths:
Pennsaid is an NSAID, and NSAIDs can increase the risk of serious heart problems, including heart attack and stroke.
The risk may be higher if you:
Use the lowest effective dose for the shortest time needed, as directed by your healthcare provider.
Pennsaid may increase the risk of stomach or intestinal bleeding, ulcers, or perforation.
These problems can occur without warning and may be serious or life-threatening. Older adults and people with a history of stomach ulcers or bleeding may be at greater risk.
Seek medical attention if you notice symptoms such as black or bloody stools, vomiting blood, or severe stomach pain.
Do not use Pennsaid right before or after coronary artery bypass graft (CABG) surgery.
NSAIDs can increase the risk of serious cardiovascular complications around the time of this procedure.
Do not use Pennsaid if you are allergic to diclofenac, aspirin, other NSAIDs, or any ingredient in the medication.
Seek immediate medical attention if you develop symptoms such as swelling of the face or throat, hives, severe rash, or difficulty breathing.
Tell your healthcare provider if you are pregnant, planning to become pregnant, or think you may be pregnant before using Pennsaid.
NSAIDs such as diclofenac should generally be avoided at around 20 weeks of pregnancy or later unless specifically recommended by a healthcare provider.
Use later in pregnancy can cause serious kidney problems in the unborn baby and may reduce the amount of amniotic fluid. NSAIDs should also be avoided later in pregnancy because they can affect the baby’s heart and cause other pregnancy complications.
Even though Pennsaid is applied to the skin, some diclofenac can still be absorbed into the bloodstream.
Do not use more than prescribed, and tell your healthcare provider if you have a history of heart disease, stomach bleeding, ulcers, or other serious medical conditions before starting treatment.
No. Pennsaid may not be suitable for everyone. Talk to your healthcare provider before using Pennsaid, especially if you have heart disease, high blood pressure, kidney problems, stomach ulcers, a history of bleeding, asthma caused by aspirin or NSAIDs, or other ongoing medical conditions.
Pennsaid may interact with certain medications. Before using it, tell your healthcare provider or pharmacist about all the medicines you take, including prescription drugs, over-the-counter medicines, vitamins, and supplements. This helps them check for possible interactions and determine whether Pennsaid is safe to use with your other treatments.
Some people may notice pain relief within the first few hours after applying Pennsaid. However, it may take several days of regular use before you notice the full benefit. Continue using it as prescribed, even if the improvement is gradual.
Pennsaid is approved to treat pain and inflammation caused by osteoarthritis of the knee. A healthcare provider may sometimes prescribe diclofenac for other conditions, but Pennsaid should only be used for another purpose if specifically recommended by your healthcare provider.
Yes. Pennsaid may interact with medications such as blood thinners, other NSAIDs, certain blood pressure medications, and some other drugs. Do not start, stop, or change any medication without first speaking with your healthcare provider or pharmacist. Even though Pennsaid is applied to the skin, some diclofenac is absorbed into the bloodstream and can still cause drug interactions.
| Generic name: | Diclofenac sodium |
|---|---|
| Formulation: | Solution |
| Strength(s): | 1.50% |
| Quantities Available: | 60mL, 120ml, 180mL |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Pennsaid (diclofenac sodium) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is standard for prescription medications to ensure continuous treatment without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Pennsaid is applied as 40 drops to each affected knee, four times daily. For a 90-day supply, you would typically order approximately 14,400 drops (160 drops per day x 1 knee x 90 days) or 28,800 drops (160 drops per day x 2 knees x 90 days).
Yes, we sell diclofenac sodium on our website. You can enjoy competitive prices for this medication. Please note that you will need a valid prescription from your healthcare provider in order for us to dispense the medication. You can conveniently submit your prescription by mail, fax, or upload it through your online account.
Yes, we ship Pennsaid (diclofenac sodium) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Pennsaid (Diclofenac sodium). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Pennsaid (Diclofenac sodium).
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