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Gleevec (active ingredient: imatinib mesylate) is a prescription medication used to treat several types of cancer and blood disorders. It belongs to a group of medications called tyrosine kinase inhibitors (TKIs), which work by blocking specific proteins that help cancer cells grow and multiply.
By targeting these abnormal proteins, Gleevec can slow or stop the growth of cancer cells and help control the progression of certain diseases.
Gleevec is used to treat Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) in adults and children.
CML is a type of blood cancer that affects the bone marrow and white blood cells. Gleevec targets the abnormal protein produced by the Philadelphia chromosome, helping to reduce the number of cancer cells and improve blood cell counts.
Gleevec is also used in combination with chemotherapy to treat Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) in children.
ALL is a fast-growing cancer of the blood and bone marrow. Gleevec helps target the abnormal leukemia cells and supports the effectiveness of chemotherapy.
Gleevec is indicated for the treatment of KIT (CD117)-positive gastrointestinal stromal tumors (GIST) that cannot be removed surgically or have spread to other parts of the body.
GIST is a rare type of tumor that develops in the digestive tract. Gleevec works by blocking signals that promote tumor growth.
Gleevec may be used to treat dermatofibrosarcoma protuberans (DFSP) when the tumor cannot be removed surgically, has returned after treatment, or has spread to other areas of the body.
DFSP is a rare cancer that develops in the skin and underlying tissues.
Gleevec is used in certain adults with:
It is particularly effective in patients whose disease is associated with specific genetic changes, such as the FIP1L1-PDGFRα fusion gene.
Gleevec may also be used to treat certain forms of systemic mastocytosis, including:
These conditions involve an abnormal buildup of mast cells, which can affect multiple organs throughout the body.
Gleevec blocks the activity of abnormal proteins called tyrosine kinases, which help certain cancer cells grow and survive.
By inhibiting these proteins, Gleevec can:
Because Gleevec targets specific cancer-related proteins, it is often referred to as a targeted therapy. Your healthcare provider will determine whether Gleevec is an appropriate treatment option based on your specific diagnosis and medical condition.
Gleevec is available as an oral tablet and should be taken exactly as prescribed by your healthcare provider.
Take Gleevec with a meal and a large glass of water to help reduce the risk of stomach irritation. Try to take the medication at the same time each day to maintain consistent levels in your body and help you remember your doses.
Swallow the tablets whole. Do not crush, chew, or break the tablets. If a tablet becomes crushed or broken, avoid direct contact with the powder whenever possible. If accidental contact occurs, wash the affected area thoroughly with soap and water.
Do not take more or less Gleevec than prescribed, and do not stop treatment without first consulting your healthcare provider.
The dose of Gleevec varies depending on the condition being treated, your response to therapy, and other individual factors.
Chronic Myeloid Leukemia (CML)
For adults with chronic-phase CML, the typical recommended dose is:
For adults with accelerated-phase CML or blast crisis, the typical recommended dose is:
Gastrointestinal Stromal Tumors (GIST)
For adults with gastrointestinal stromal tumors (GIST), the typical recommended dose is:
Your healthcare provider may adjust the dose based on your response to treatment and individual needs.
Dermatofibrosarcoma Protuberans (DFSP)
For adults with dermatofibrosarcoma protuberans (DFSP), the typical recommended dose is:
Pediatric Patients
For children, the dosage is individualized and is based on factors such as:
Your child’s healthcare provider will determine the most appropriate dose.
Regular blood tests and follow-up appointments are important during treatment to monitor your response to Gleevec and help manage any potential side effects.
Gleevec (Imatinib) is available in the following forms and strength:
Before taking Gleevec (imatinib), tell your healthcare provider about your complete medical history, including any allergies, medical conditions, and medications you are taking.
Avoid eating grapefruit or drinking grapefruit juice while taking Gleevec unless your healthcare provider specifically tells you it is safe to do so.
Grapefruit can affect how your body processes imatinib, which may increase the risk of side effects. If you have questions about grapefruit or other foods that may interact with your medication, speak with your healthcare provider or pharmacist.
Gleevec may cause:
Until you know how the medication affects you, avoid driving, operating machinery, or performing activities that require alertness and clear vision.
If these symptoms become severe or persistent, contact your healthcare provider.
Tell your healthcare provider if you are allergic to imatinib, any other medications, or any of the ingredients in Gleevec.
Stop taking Gleevec and seek immediate medical attention if you develop signs of a serious allergic reaction, such as:
Tell your healthcare provider if you are breastfeeding or planning to breastfeed.
Breastfeeding is not recommended while taking Gleevec and for at least one month after your final dose, as the medication may pass into breast milk and could harm a nursing infant.
Your healthcare provider can discuss safe feeding options for your baby during treatment.
Before starting Gleevec, tell your healthcare provider if you have ever had:
Certain medical conditions may increase the risk of side effects or require additional monitoring during treatment.
Gleevec can cause serious liver problems, including severe liver injury and, in rare cases, liver failure.
Your healthcare provider will typically check your liver function before treatment begins and may monitor it regularly during treatment, especially if you are also receiving chemotherapy or other medications that can affect the liver.
Contact your healthcare provider immediately if you develop symptoms of liver problems, including:
Regular blood tests are an important part of treatment and help your healthcare provider monitor for potential liver-related side effects.
Always attend scheduled follow-up appointments and laboratory testing while taking Gleevec.
While taking Gleevec (imatinib), avoid eating grapefruit or drinking grapefruit juice unless your healthcare provider advises otherwise. Grapefruit can increase the amount of imatinib in your body and may raise the risk of side effects. Gleevec may also cause drowsiness, dizziness, or blurred vision. Until you know how the medication affects you, avoid driving, operating machinery, or performing activities that require alertness and clear vision.
If you experience side effects while taking Gleevec, contact your healthcare provider. Depending on the type and severity of the side effects, your healthcare provider may adjust your dosage, monitor your symptoms more closely, recommend treatments to help manage side effects, or modify your treatment plan if necessary. Do not stop taking Gleevec without first consulting your healthcare provider unless you are specifically instructed to do so.
Gleevec is a targeted cancer therapy that belongs to a class of medications called tyrosine kinase inhibitors (TKIs). It works by blocking specific proteins that send signals telling cancer cells to grow and divide. By interfering with these signals, Gleevec helps slow or stop the growth of cancer cells and may help prevent the disease from progressing. This targeted approach allows Gleevec to treat certain cancers and blood disorders that are driven by specific genetic or cellular abnormalities.
| Generic name: | Imatinib |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 100mg, 400mg |
| Quantities Available: | 30, 90, 120, 180 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Gleevec (imatinib mesylate) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time. This quantity is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Gleevec is commonly prescribed in dosages of 100 mg or 400 mg, taken once daily or as directed by your healthcare provider. For a 90-day supply, if your prescribed dosage is 400 mg daily, you would order 90 tablets (90 days x 1 tablet per day).
Yes, we do sell imatinib mesylate! At our website, you can enjoy low prices on this medication. However, it’s important to note that you will need a valid prescription from your healthcare provider in order for us to dispense the medication. You can easily submit your prescription by mailing, faxing, or uploading it through your online account.
Yes, we ship Gleevec (imatinib mesylate) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Gleevec (Imatinib). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Gleevec (Imatinib).
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