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Isentress (Raltegravir) Shopper Approved

Prescription Prescription Required FormationFormulation: Chewable Tablet

Isentress

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Prescription Prescription Required FormationFormulation: Chewable Tablet

Raltegravir

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Isentress contains the active ingredient raltegravir. It is a prescription antiretroviral medication used to treat HIV-1 infection.

It is used together with other HIV medicines, because combination treatment is needed to control the virus effectively.

HIV-1 Infection

Isentress is used for the treatment of HIV-1 infection in adults and certain pediatric patients.

Depending on the formulation, it may be prescribed for children who meet specific age and weight requirements. Your healthcare provider will choose the appropriate product and dose based on the patient’s age, weight, and treatment needs.

How Isentress Helps Control HIV

HIV attacks the immune system, especially CD4 cells, which help the body fight infections.

Without treatment, HIV can continue multiplying and gradually weaken the immune system.

Isentress helps slow this process by preventing the virus from making new copies of itself.

How Isentress Works

Raltegravir belongs to a class of HIV medicines called integrase strand transfer inhibitors, or INSTIs.

HIV uses an enzyme called integrase to insert its genetic material into human cells.

Blocking the Integrase Enzyme

Isentress blocks the activity of HIV integrase.

When integrase is blocked, the virus has difficulty inserting its genetic material into the DNA of infected cells. This interrupts an important step in the HIV life cycle.

Reducing Viral Load

By preventing HIV from multiplying efficiently, Isentress can help reduce the amount of virus in the blood.

The amount of HIV in the blood is called the viral load.

With effective combination treatment, the goal is usually to reduce the viral load to a very low or undetectable level.

Supporting the Immune System

As viral load decreases, the immune system has a better chance to recover and remain stronger.

This may allow the CD4 cell count to increase or remain stable, helping the body fight infections more effectively.

Isentress Must Be Used With Other HIV Medicines

Isentress should not normally be used by itself.

It is taken as part of a combination antiretroviral treatment regimen. Using several HIV medicines together helps control the virus more effectively and reduces the chance of drug resistance.

Isentress Does Not Cure HIV

Isentress does not cure HIV infection.

However, taking it consistently with the rest of your HIV treatment can help keep the virus controlled, protect the immune system, and reduce the risk of HIV-related complications.

Consistent Treatment Is Important

Take Isentress exactly as prescribed and avoid skipping doses.

Missing doses can allow HIV to multiply again and may increase the risk that the virus becomes resistant to treatment.

Regular Monitoring

Your healthcare provider may regularly check your viral load, CD4 count, and overall response to treatment while you are taking Isentress.

These tests help determine how well your HIV treatment is working.

Isentress is taken by mouth, usually once or twice daily depending on the formulation and your treatment plan.

It can generally be taken with or without food. Follow the exact instructions provided by your healthcare provider.

Swallow the Tablet as Directed

Swallow the tablet whole with water.

Do not split, crush, or chew the tablet unless your healthcare provider or pharmacist confirms that your specific formulation can be taken that way.

Take Isentress Consistently

Try to take Isentress at the same time or times each day.

Consistent dosing helps maintain an effective amount of raltegravir in your body and improves the ability of your HIV treatment to keep the virus under control.

Do Not Stop Treatment on Your Own

Do not stop Isentress without speaking with your healthcare provider.

Stopping treatment or frequently missing doses can allow HIV to multiply again and may increase the risk of drug resistance, which can make the infection harder to treat.

Avoid Certain Antacids

Antacids containing aluminum or magnesium can reduce the absorption of raltegravir and make Isentress less effective.

Ask your healthcare provider or pharmacist before using any antacid while taking Isentress.

Usual Adult Dose

For many adults taking the standard Isentress formulation, the usual dose is 400 mg twice daily.

Some patients may use a different raltegravir formulation with a different dosing schedule, so it is important to follow the instructions for the exact product prescribed.

Use With Rifampin

Rifampin can reduce raltegravir levels in the body.

When standard Isentress is used with rifampin, a healthcare provider may increase the raltegravir dose to 800 mg twice daily.

Do not make this adjustment on your own.

Dosing in Children

The pediatric dose of Isentress depends on the child’s weight, age, and formulation being used.

Children weighing 25 kg or more may sometimes receive the adult tablet dose, while smaller children generally need a weight-based dose.

Your child’s healthcare provider will calculate the correct amount.

Different Formulations Are Not Automatically Interchangeable

Raltegravir is available in different formulations, including standard tablets and other pediatric or once-daily products.

These formulations may have different strengths and dosing instructions, so do not switch between them without medical guidance.

If You Miss a Dose

If you miss a dose, take it when you remember unless it is almost time for your next scheduled dose.

If the next dose is close, skip the missed dose and continue with your regular schedule.

Do not take two doses at the same time to make up for a missed dose.

Getting the Best Results

Take Isentress exactly as prescribed, use it consistently with your other HIV medicines, and avoid medications that may interfere with raltegravir unless your healthcare provider approves them.

Regular viral load and CD4 testing can help show how well your treatment is working.

Common Side Effects of Isentress (Raltegravir):

  • Chest pain
  • Diarrhea
  • Dizziness
  • Headache
  • Loss of appetite
  • Mouth sores
  • Nausea
  • Sleep problems (insomnia)
  • Stomach pain
  • Tired feeling
  • Vomiting
  • Weight loss

Serious Side Effects of Isentress (Raltegravir):

  • Anxiety
  • Burning in your eyes
  • Clay-colored stools
  • Cold sores
  • Dark urine
  • Difficulty breathing
  • Dry cough
  • Extreme tiredness
  • Fever
  • General ill feeling
  • Hives
  • Impotence
  • Irritableness
  • Loss of interest in sex
  • Menstrual changes
  • Muscle or joint pain
  • Muscle pain
  • Night sweats
  • Prickly feeling
  • Problems with balance or eye movement
  • Rapid heart rate
  • Shortness of breath
  • Skin pain
  • Sores on your genital or anal area
  • Swelling in your neck or throat (enlarged thyroid)
  • Swelling of your face, lips, tongue, or throat
  • Swollen glands
  • Tenderness
  • Weakness
  • Wheezing
  • Yellowing of the skin or eyes

Isentress (Raltegravir) is available in the following forms and strength:

Isentress: Tablet

  • 100 mg
  • 400 mg

Allergic Reactions

Do not take Isentress if you are allergic to raltegravir or any ingredient in the medication.

Seek immediate medical attention if you develop swelling of the face, lips, tongue, or throat, severe rash, or difficulty breathing.

Medication Interactions

Isentress can interact with certain medications.

Tell your healthcare provider about all prescription medicines, over-the-counter products, vitamins, supplements, and herbal products you take before starting treatment.

Some medicines can change how much raltegravir is absorbed or how quickly it is removed from the body.

Pregnancy

If you are pregnant, planning to become pregnant, or think you may be pregnant, talk to your healthcare provider before taking Isentress.

Your provider will consider the benefits of keeping HIV well controlled and any potential risks when choosing your treatment.

Breastfeeding

People with HIV should discuss breastfeeding carefully with their healthcare provider.

Raltegravir may pass into breast milk, and recommendations may also depend on the risk of HIV transmission, the infant’s health, and local medical guidance.

Liver Problems

Tell your healthcare provider if you have liver disease, hepatitis B, hepatitis C, or abnormal liver test results.

Isentress can sometimes affect liver function, so your provider may recommend blood tests during treatment.

Severe Skin Reactions

Rarely, Isentress can cause serious skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis.

Seek urgent medical attention if you develop a severe or spreading rash, blistering, peeling skin, sores in the mouth, fever, or swelling of the face.

Muscle Problems

Isentress has rarely been associated with myopathy and rhabdomyolysis, which involve muscle injury.

Contact your healthcare provider if you develop unexplained muscle pain, tenderness, weakness, or dark-colored urine.

The risk may be higher if you already have a muscle disorder or take other medicines that can affect muscles.

Immune Reconstitution Syndrome

When effective HIV treatment begins, the immune system may become stronger and start reacting to infections that were already present but not causing noticeable symptoms.

This is called immune reconstitution syndrome.

Contact your healthcare provider if you develop new or worsening symptoms after starting Isentress.

Mood or Behavior Changes

Changes in mood or behavior have been reported in some people taking raltegravir.

Tell your healthcare provider if you notice significant changes in mood, sleep, behavior, or thinking while taking Isentress.

Kidney Problems

Raltegravir is not mainly removed through the kidneys, so kidney disease does not usually require a routine dose adjustment.

However, tell your healthcare provider if you have kidney problems, especially if you develop severe muscle symptoms that could affect kidney function.

Bone Problems

Cases of osteonecrosis, which is damage to bone tissue caused by reduced blood supply, have been reported in people receiving combination HIV treatment.

The condition can have several causes and is not specific to Isentress. Contact your healthcare provider if you develop persistent joint pain, stiffness, or difficulty moving.

Use in Children

Isentress can be used in certain pediatric patients, with the dose based on age, weight, and formulation.

Children should receive the exact product and dose prescribed by a healthcare provider because different raltegravir formulations are not automatically interchangeable.

Regular Monitoring

While taking Isentress, your healthcare provider may monitor your viral load, CD4 count, liver function, and overall response to treatment.

Regular follow-up helps make sure your HIV treatment continues to work safely and effectively.

Is Isentress a cure for HIV?

No. Isentress does not cure HIV. It helps control the virus by reducing the amount of HIV in the blood. When taken consistently with other antiretroviral medicines, it can help protect the immune system and lower the risk of HIV-related complications.

How is Isentress taken?

Isentress is taken by mouth, usually once or twice daily depending on the formulation prescribed. Take it exactly as directed by your healthcare provider and use it consistently with the rest of your HIV treatment.

How effective is Isentress?

Isentress can be very effective when it is taken correctly as part of a combination antiretroviral treatment plan. It can help lower the viral load and allow CD4 cells to increase or remain stable, which helps the immune system function more effectively.

Can Isentress be taken with food?

Yes. Isentress can generally be taken with or without food. Try to take it consistently and follow any specific instructions your healthcare provider gives you for your formulation.

REVIEWS

Additional Information Book
Generic name:

Raltegravir

Formulation:

Chewable Tablet, Tablet

Strength(s):

100mg, 400mg

Quantities Available:

60, 120

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Isentress can I order at once from a Canadian pharmacy?

When ordering Isentress (raltegravir) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Isentress is commonly prescribed in dosages of 100 mg or 400 mg twice daily. For a 90-day supply, this means you would order 180 tablets (90 days x 2 tablets per day).

Do you sell raltegravir?

No, we do not sell raltegravir on our website. However, you can still enjoy low prices on Isentress, which contains raltegravir as an active ingredient. You will need a valid prescription from your healthcare provider to purchase Isentress. We require this prescription to dispense the medication. You can mail, fax, or upload your prescription through your online account for processing.

Do you offer shipping of Isentress (raltegravir) to the United States?

Yes, we ship Isentress (raltegravir) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Isentress (Raltegravir). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Isentress (Raltegravir).