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Formulation: Soft Capsule
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Prometrium contains micronized progesterone, a form of progesterone that is similar to the hormone naturally produced by the body. It is available by prescription and may be used as part of hormone therapy or to help restart menstrual bleeding in certain patients.
Progesterone plays an important role in regulating the menstrual cycle, controlling the growth of the uterine lining, and supporting the early stages of pregnancy.
Prometrium may be prescribed to postmenopausal women who still have a uterus and are taking estrogen hormone therapy.
Estrogen helps relieve menopausal symptoms such as hot flashes, night sweats, vaginal dryness, and discomfort during sex. However, taking estrogen by itself can cause the lining of the uterus, called the endometrium, to become too thick.
Over time, excessive thickening of the uterine lining may lead to endometrial hyperplasia. In some cases, this condition can develop into endometrial cancer.
Prometrium helps balance the effects of estrogen on the uterus. It causes the uterine lining to mature and shed rather than continuing to grow. This helps lower the risk of abnormal thickening and cancer of the uterine lining.
Prometrium does not usually provide most of the relief from hot flashes, night sweats, or vaginal dryness. Estrogen is generally the part of hormone therapy that treats these symptoms. Prometrium is mainly added to protect the uterus.
Women who have had their uterus removed usually do not need progesterone solely for protection of the uterine lining. However, individual treatment plans may vary.
Prometrium may also be prescribed for secondary amenorrhea. This means menstrual periods have stopped in someone who previously had periods.
A missed or absent period can have many possible causes, including pregnancy, hormonal changes, significant changes in weight, intense exercise, thyroid problems, polycystic ovary syndrome, ovarian conditions, or certain medications.
Your healthcare provider will usually investigate the cause before prescribing treatment.
When Prometrium is used for secondary amenorrhea, it is generally taken for a limited number of days. After treatment ends, the drop in progesterone may cause the uterine lining to shed. This is called withdrawal bleeding and may resemble a menstrual period.
A withdrawal bleed does not necessarily mean that the underlying cause of the missed periods has been corrected. Additional testing or treatment may still be needed.
During a natural menstrual cycle, estrogen causes the uterine lining to grow. After ovulation, progesterone helps stabilize and prepare this lining for a possible pregnancy.
If pregnancy does not occur, progesterone levels fall and the uterine lining is shed as a menstrual period.
Prometrium produces effects similar to natural progesterone. It can:
Prometrium contains micronized progesterone rather than a synthetic progestin. Micronization reduces the progesterone into very small particles, helping the body absorb it when it is taken by mouth.
Although progesterone and synthetic progestins have similar purposes, they are not identical. Their side effects, dosing schedules, and effects on the body may differ.
When Prometrium is used with estrogen, you may not feel it working. Its main purpose is to protect the uterine lining over time.
Depending on your schedule, you may experience monthly bleeding or spotting. Some patients take progesterone only during part of each month, while others use it every day.
When it is used for secondary amenorrhea, withdrawal bleeding may occur within several days after the final dose. Contact your healthcare provider if bleeding does not occur or if it is unusually heavy or prolonged.
Tell your healthcare provider if you have unexplained vaginal bleeding, a history of breast cancer or another hormone-sensitive cancer, blood clots, stroke, heart attack, liver disease, or an allergy to progesterone or any ingredient in the capsules.
Prometrium may cause dizziness or drowsiness. It is often taken at bedtime to reduce the effect of these symptoms during the day.
Report any unusual vaginal bleeding promptly, especially after menopause. Attend regular follow-up appointments so your healthcare provider can review your symptoms, bleeding pattern, treatment response, and ongoing need for hormone therapy.
Take Prometrium exactly as prescribed. Do not change the dose, treatment schedule, or length of use without speaking with your healthcare provider.
Prometrium is available as a soft gelatin capsule that you take by mouth. It is usually taken once a day at bedtime because it can cause drowsiness, dizziness, or lightheadedness.
Take Prometrium exactly as prescribed. Your dose and treatment schedule will depend on why you are taking it, whether you are also using estrogen, your medical history, and how your body responds.
Swallow the capsule whole with a full glass of water. Do not open, crush, chew, or dissolve it.
Take the capsule while sitting or standing upright. If you have difficulty swallowing capsules, speak with your healthcare provider or pharmacist rather than changing how you take the medication.
Prometrium may be taken with or without food, but follow the instructions on your prescription label. Taking oral micronized progesterone with food can increase the amount absorbed by your body, so it is important to take it consistently in the same way each day.
Prometrium can make you feel sleepy, dizzy, or unsteady. Taking it at bedtime may make these effects less disruptive during the day.
After taking your dose, avoid driving, operating machinery, or doing anything that requires full alertness. Be careful when getting out of bed during the night, as dizziness may increase the risk of falling.
If you still have your uterus and are taking estrogen after menopause, your healthcare provider may prescribe Prometrium to protect the uterine lining.
The usual regimen is 200 mg once daily at bedtime for 12 consecutive days during each 28-day treatment cycle.
Estrogen causes the uterine lining to grow. Progesterone helps control this growth and lowers the risk of endometrial hyperplasia, which is abnormal thickening of the uterine lining.
After completing the 12-day course, you may experience bleeding or spotting. This is called withdrawal bleeding and occurs because progesterone levels fall after the medication is stopped for the remainder of the cycle.
Your healthcare provider will tell you which 12 days of the cycle to take Prometrium. Marking the treatment days on a calendar or setting reminders may help you follow the schedule correctly.
When Prometrium is prescribed for secondary amenorrhea, the usual dose is 400 mg once daily at bedtime for 10 consecutive days.
Secondary amenorrhea means that menstrual periods have stopped in someone who previously had periods.
After the 10-day treatment course ends, a withdrawal bleed may occur within several days. However, the timing can vary from one person to another.
Contact your healthcare provider if:
A withdrawal bleed does not necessarily mean that the underlying cause of the missed periods has been corrected. Your healthcare provider may still need to investigate why your periods stopped.
Take the missed dose when you remember, unless it is almost time for your next scheduled dose.
If your next dose is approaching, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
If you are following a 10-day or 12-day treatment schedule, contact your healthcare provider or pharmacist if you miss a dose. They can tell you whether to extend the course or continue with the original end date.
Do not take Prometrium for extra days, increase your dose, or skip scheduled treatment days without speaking with your healthcare provider.
The timing of progesterone treatment is important, especially when it is being used to protect the uterine lining during estrogen therapy.
Prometrium may cause drowsiness, dizziness, breast tenderness, bloating, headache, or changes in vaginal bleeding.
Contact your healthcare provider if side effects are severe, persistent, or interfere with your daily activities.
Report any unusual vaginal bleeding promptly, especially if you are postmenopausal. Attend regular follow-up appointments so your healthcare provider can review your bleeding pattern, treatment response, and ongoing need for therapy.
Prometrium (Progesterone) is available in the following forms and strength:
Serious risks when Prometrium is used with estrogen
Prometrium is often taken together with estrogen as part of hormone therapy. Estrogen combined with a progestogen may increase the risk of serious health problems, including blood clots, stroke, heart attack, and breast cancer.
These risks do not affect everyone equally. Your individual risk depends on factors such as your age, medical history, dose, length of treatment, and whether you have other risk factors for heart disease, cancer, or blood clots.
Hormone therapy should not be used specifically to prevent heart disease, heart attacks, strokes, or dementia. Your healthcare provider will consider the possible benefits and risks before recommending treatment.
Studies involving women aged 65 and older found an increased risk of probable dementia with certain estrogen-plus-progestogen treatments.
It is unclear whether the same risk applies to younger postmenopausal women or to every type of hormone therapy. Prometrium should not be taken specifically to prevent memory loss or dementia.
Before taking Prometrium, tell your healthcare provider about your complete medical history.
Prometrium may not be suitable if you have or have previously had:
Prometrium capsules contain peanut oil and must not be used by anyone with a peanut allergy.
Smoking does not have a specific interaction with progesterone alone. However, smoking can independently increase the risk of heart attack, stroke, blood clots, and high blood pressure.
These risks may be especially important when Prometrium is taken with estrogen. Tell your healthcare provider if you smoke, vape nicotine, or use other nicotine products. They can discuss your individual risks and provide support to help you quit.
Prometrium can interact with certain prescription medications, nonprescription products, and herbal supplements. Some combinations may change the amount of progesterone in your body or increase side effects such as dizziness and drowsiness.
Before starting treatment, tell your healthcare provider and pharmacist about everything you take. Do not start, stop, or change another medication without first asking a healthcare professional.
Prometrium may cause side effects such as:
Taking Prometrium at bedtime may make dizziness and drowsiness less disruptive. Avoid driving or operating machinery until you know how the medication affects you.
Contact your healthcare provider if a side effect is severe, persistent, or interferes with your daily activities.
Seek immediate medical attention if you develop chest pain, sudden shortness of breath, coughing up blood, pain or swelling in one leg, a sudden severe headache, difficulty speaking, sudden vision changes, or weakness on one side of your body.
Take Prometrium only for the condition and schedule prescribed by your healthcare provider. Do not use it to prevent heart disease, stroke, dementia, or another condition for which it was not prescribed.
Your healthcare provider should regularly review your symptoms, bleeding pattern, treatment response, and ongoing need for hormone therapy. Use the medication exactly as directed and discuss any concerns about its risks or benefits before changing your treatment.
Prometrium contains micronized progesterone, a hormone similar to the progesterone naturally produced by the body. It may be prescribed to help protect the lining of the uterus in postmenopausal women who are taking estrogen therapy. It may also be used to treat secondary amenorrhea, which means menstrual periods have stopped in someone who previously had periods.
Prometrium is taken by mouth, usually once daily at bedtime. Taking it at bedtime may help because the medication can cause drowsiness or dizziness. Your dose and treatment schedule will depend on why you are taking it. Follow your healthcare provider’s instructions carefully and swallow the capsule whole.
No. Prometrium is not a contraceptive and should not be used to prevent pregnancy. Use a reliable form of birth control when pregnancy prevention is needed. Ask your healthcare provider which option is appropriate for you.
Prometrium is not routinely prescribed for use during pregnancy under its standard approved indications. However, progesterone may sometimes be used during fertility treatment or early pregnancy for specific medical reasons. The appropriate product, dose, and method of administration depend on the individual situation. Do not take Prometrium during pregnancy unless it has been specifically prescribed by a healthcare provider who is supervising your care. Tell your healthcare provider promptly if you are pregnant, think you may be pregnant, or are planning a pregnancy.
| Generic name: | Progesterone |
|---|---|
| Formulation: | Soft Capsule, Soft Gel Caps, Soft Gel Capsules |
| Strength(s): | 100mg |
| Quantities Available: | 30, 90, 100, 180 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Prometrium (progesterone) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is standard for prescription medications to ensure continuous management of medical conditions without the need for frequent refills.
Here’s what you need to know:
Dosage and Quantity: Prometrium is available in a 100 mg capsule form. The typical maximum dosage for Prometrium is around 400 mg per day, depending on your specific medical condition and your doctor’s prescription guidelines.
For a 90-day supply at the maximum dosage of 400 mg per day, you would order 360 capsules (90 days x 4 capsules per day).
Yes, we sell progesterone on our website and you can enjoy competitive prices. To purchase progesterone from us, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and legally. You have the option to submit your prescription by mail, fax, or upload it through your online account for convenient processing.
Yes, we ship Prometrium (progesterone) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Prometrium (Progesterone). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Prometrium (Progesterone).
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