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Estrace (Estradiol) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet

Estrace

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Prescription Prescription Required FormationFormulation: Tablet

Estradiol

(Generic Alternative)

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Estrace (active ingredient: estradiol) is a prescription medication used to replace estrogen, a hormone that naturally declines during menopause. By restoring estrogen levels, Estrace helps relieve symptoms caused by estrogen deficiency and improves the health of vaginal and vulvar tissues.

Estrace is commonly prescribed for the following conditions:

Hormone Replacement Therapy (HRT)

Estrace is used as hormone replacement therapy (HRT) to help relieve moderate to severe menopausal symptoms in women.

As estrogen levels decrease during menopause, many women experience symptoms that can affect their comfort and quality of life, including:

  • Hot flashes.
  • Night sweats.
  • Vaginal dryness.
  • Vaginal itching or burning.
  • Discomfort during daily activities.

By replacing the estrogen your body no longer produces in sufficient amounts, Estrace can help reduce these symptoms and improve overall comfort and well-being.

Vulvar and Vaginal Atrophy

Estrace is also used to treat vulvar and vaginal atrophy, a condition that occurs when estrogen levels decline after menopause.

Low estrogen levels can cause the tissues of the vagina and vulva to become thinner, drier, and less elastic. This may lead to symptoms such as:

  • Vaginal dryness.
  • Vaginal itching or irritation.
  • Burning or discomfort.
  • Pain during sexual intercourse (dyspareunia).
  • Certain urinary symptoms, such as discomfort during urination or increased urinary urgency.

By restoring estrogen to these tissues, Estrace helps improve moisture, thickness, and elasticity, making everyday activities and sexual intercourse more comfortable.

How Does Estrace Work?

Estrace belongs to a group of medications called estrogen hormones.

Its active ingredient, estradiol, is a form of estrogen that is chemically identical to the estrogen naturally produced by the ovaries before menopause.

As estrogen levels decline with menopause or other conditions that cause estrogen deficiency, symptoms such as hot flashes, vaginal dryness, and thinning of the vaginal tissues can develop.

Estrace works by replacing the missing estrogen, helping to:

  • Reduce hot flashes and night sweats.
  • Relieve vaginal dryness, itching, and burning.
  • Improve the thickness, moisture, and elasticity of vaginal tissues.
  • Reduce pain during sexual intercourse.
  • Improve urinary symptoms related to estrogen deficiency.
  • Restore comfort and improve quality of life for women experiencing menopausal symptoms.

Many women begin to notice an improvement in their symptoms within a few weeks of starting treatment, although the full benefits may take longer depending on the condition being treated and the dosage prescribed.

Estrace is available in different formulations, including oral tablets and vaginal cream. Always use the formulation prescribed by your healthcare provider and follow their instructions carefully.

Estrace Tablets

If you have been prescribed Estrace tablets, take the medication by mouth with or without food. If the tablets upset your stomach, taking them with food or immediately after a meal may help reduce stomach discomfort.

Swallow the tablet whole with water. Do not crush, chew, or split the tablet unless your healthcare provider instructs you to do so, as this may affect how the medication works.

Take Estrace at the same time each day to help maintain consistent hormone levels in your body.

Estrace Vaginal Cream

If you have been prescribed Estrace vaginal cream to treat vulvar or vaginal atrophy, apply it exactly as directed by your healthcare provider using the applicator provided.

The typical dosing schedule is:

  • Starting dose: Apply 2 to 4 grams of cream into the vagina once daily for 1 to 2 weeks.
  • Dose reduction: Your healthcare provider will gradually reduce the dose to half of the starting dose for the next 1 to 2 weeks.
  • Maintenance dose: Once your symptoms improve, the usual maintenance dose is 1 gram applied one to three times per week.

Your healthcare provider may adjust your dose and treatment schedule based on your symptoms, response to treatment, and overall health. Always use the lowest effective dose for the shortest duration needed to manage your symptoms.

Note: The dosing schedule above applies to Estrace vaginal cream, not the oral tablets. If you are unsure which formulation you have been prescribed, ask your healthcare provider or pharmacist before using the medication.

Common Side Effects of Estrace (Estradiol):

  • Bloating
  • Breast tenderness
  • Changes in menstrual period
  • Headache
  • Nausea
  • Stomach cramps
  • Stomach upset
  • Vomiting
  • Weight changes

Serious Side Effects of Estrace (Estradiol):

  • Breast lumps
  • Mental or mood changes
  • Persistent nausea and vomiting
  • Severe abdominal pain
  • Signs of blood clots (chest pain, severe headache, weakness on one side of the body, trouble speaking, sudden vision changes, trouble breathing, confusion)
  • Swelling of the hands and feet
  • Unusual vaginal bleeding

Estrace (Estradiol) is available in the following forms and strength:

Estrace: Tablet

  • 0.5 mg
  • 1 mg
  • 2 mg

Estradiol: Tablet

  • 0.5 mg
  • 1 mg

Before using Estrace, tell your healthcare provider about your complete medical history, including any current or past medical conditions. Estrace may not be suitable for everyone, and certain conditions can increase the risk of serious side effects.

Do Not Use Estrace If You Have Certain Medical Conditions

Do not use Estrace if you have:

  • Unexplained or undiagnosed vaginal bleeding.
  • Liver disease.
  • A bleeding or blood clotting disorder.
  • A current or previous blood clot.
  • A history of heart attack or stroke.
  • Breast cancer or a history of breast cancer.
  • Cancer of the uterus, cervix, or vagina, or another estrogen-dependent cancer.
  • A known allergy to estradiol or any of the ingredients in Estrace.

Tell your healthcare provider if you have any of these conditions before starting treatment.

Smoking Increases the Risk of Serious Side Effects

Smoking while using estrogen-containing medications, including Estrace, can significantly increase your risk of:

  • Blood clots.
  • Stroke.
  • Heart attack.
  • High blood pressure.

The risk is especially high in women over 35 years of age. If you smoke or use tobacco products, talk to your healthcare provider about quitting before starting Estrace.

Sun Sensitivity and Skin Discoloration

Estrace may cause melasma, a condition that results in dark, blotchy patches of skin, most commonly on the face. Sunlight can make these patches more noticeable.

While using Estrace:

  • Limit your time in direct sunlight.
  • Avoid tanning beds and sunlamps.
  • Wear protective clothing, a wide-brimmed hat, and sunglasses when outdoors.
  • Apply a broad-spectrum sunscreen with an appropriate SPF whenever you are outside.

Pregnancy

Do not use Estrace during pregnancy. If you become pregnant or think you may be pregnant while using this medication, stop using it and contact your healthcare provider immediately.

If you are using Estrace and pregnancy is possible, discuss appropriate birth control options with your healthcare provider.

Allergic Reactions

Do not use Estrace if you are allergic to estradiol or any of the inactive ingredients in the medication.

Seek emergency medical attention immediately if you develop signs of a serious allergic reaction, including:

  • Rash or hives.
  • Severe itching.
  • Swelling of the face, lips, tongue, or throat.
  • Severe dizziness.
  • Difficulty breathing or swallowing.

Stop using Estrace and seek immediate medical care if any of these symptoms occur.

Is Estrace safe to use?

Yes. Estrace is generally considered safe and effective when used exactly as prescribed by your healthcare provider. However, like all medications, it can cause side effects and may not be appropriate for everyone. Before starting treatment, tell your healthcare provider about your complete medical history and any allergies you may have, including an allergy to estradiol or any of the inactive ingredients in the medication.

What should I do if I have an allergic reaction to Estrace?

Stop using Estrace and seek emergency medical attention immediately if you develop signs of a serious allergic reaction. Symptoms may include rash or hives, itching, swelling of the face, lips, tongue, or throat, severe dizziness, or difficulty breathing or swallowing. These symptoms require immediate medical care.

What is the usual dosage of Estrace?

The appropriate dose of Estrace depends on the condition being treated, the severity of your symptoms, and your individual response to therapy. For oral Estrace tablets, a common starting dose is 0.5 mg once daily. If needed, your healthcare provider may gradually increase the dose to 1 mg daily or another dose that best controls your symptoms. Your healthcare provider will prescribe the lowest effective dose for the shortest duration necessary to manage your condition.

Should I take Estrace with food?

Estrace tablets may be taken with or without food. However, if the medication causes stomach upset, taking it with food or immediately after a meal may help reduce discomfort.

Does Estrace interact with other medications?

Yes. Estrace can interact with certain prescription medications, over-the-counter medicines, vitamins, and herbal supplements. For example, it may interact with blood thinners such as warfarin, as well as other medications that affect hormone levels or liver function. Before starting Estrace, tell your healthcare provider about all medications and supplements you are taking so they can check for possible drug interactions.

Are there any risks associated with taking Estrace?

Like all estrogen-containing medications, Estrace carries certain risks, particularly with long-term use or in women with specific medical conditions. Potential risks may include an increased risk of blood clots, stroke, heart attack, breast cancer, and, in some cases, ovarian cancer. Your healthcare provider will carefully weigh the benefits and potential risks before prescribing Estrace. To help ensure the medication remains safe and effective, attend all recommended follow-up appointments and report any unusual symptoms, such as chest pain, sudden shortness of breath, severe headaches, vision changes, or unusual vaginal bleeding, to your healthcare provider immediately.

REVIEWS

Additional Information Book
Generic name:

Estradiol, Estradiol Valerate

Formulation:

Tablet

Strength(s):

0.5mg, 1mg, 2mg

Quantities Available:

84, 90, 100, 112

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Estrace can I order at once from a Canadian pharmacy?

When ordering Estrace (estradiol) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of menopausal symptoms without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Estrace is commonly prescribed in dosages of 0.5 mg, 1 mg, or 2 mg, taken once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).

Do you sell estradiol?

Yes, we sell estradiol! You can enjoy low prices on this medication by ordering from our website. To place an order, you will need a valid prescription from your healthcare provider, which we require to dispense the medication safely and accurately. You can submit your prescription by mail, fax, or by uploading it through your online account.

Do you offer shipping of Estrace (estradiol) to the United States?

Yes, we ship Estrace (estradiol) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Estrace (Estradiol). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Estrace (Estradiol).