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Avanafil

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Stendra contains the active ingredient avanafil. It is a prescription medication used to treat erectile dysfunction in adult men.

Erectile Dysfunction

Stendra is used to treat erectile dysfunction (ED), a condition in which a person has difficulty getting or keeping an erection firm enough for sexual activity.

ED can have many possible causes, including:

  • Reduced blood flow to the penis
  • Diabetes
  • High blood pressure
  • Heart or blood vessel disease
  • Certain medications
  • Stress or other emotional factors

Stendra may help improve erectile function when sexual stimulation occurs.

How Stendra Works

Stendra belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors.

During sexual stimulation, the body releases nitric oxide, which helps increase levels of a chemical called cyclic guanosine monophosphate, or cGMP.

cGMP helps relax the smooth muscles and blood vessels in the penis, allowing more blood to flow into the area.

Stendra blocks the PDE5 enzyme that normally breaks down cGMP. This allows cGMP to remain active longer, which can help improve blood flow and support an erection.

Sexual Stimulation Is Still Needed

Stendra does not automatically cause an erection.

Sexual stimulation is still required for the medication to work. Without sexual stimulation, Stendra will not normally produce an erection on its own.

When Stendra May Start Working

Stendra is a relatively fast-acting PDE5 inhibitor.

Depending on the prescribed dose, it may be taken about 15 to 30 minutes before sexual activity.

The response can vary from person to person, so follow the timing instructions given by your healthcare provider.

Important Limitation

Stendra helps treat the symptoms of erectile dysfunction, but it does not cure the underlying cause.

If erectile dysfunction continues or becomes worse, speak with your healthcare provider. ED can sometimes be related to other health conditions, including diabetes or cardiovascular disease, that may also need to be evaluated.

Stendra is taken by mouth as needed before sexual activity.

It may be taken with or without food. However, a high-fat meal may delay how quickly the medication starts working.

Take Stendra exactly as directed by your healthcare provider.

Recommended Dose

Starting dose: 100 mg.

Dose range: 50 mg to 200 mg, depending on how well the medication works and whether you develop side effects.

Maximum frequency: Do not take Stendra more than once in a 24-hour period.

Your healthcare provider will choose the most appropriate dose based on your medical history, response to treatment, and other medications you use.

When to Take Stendra

The timing depends on the dose prescribed.

A 100 mg or 200 mg dose may be taken about 15 minutes before sexual activity.

A 50 mg dose is generally taken about 30 minutes before sexual activity.

Sexual stimulation is still needed for Stendra to work.

What to Do If You Miss a Dose

Stendra is taken as needed, not on a regular daily schedule, so there is usually no missed dose to make up.

If you planned to take Stendra before sexual activity but forgot, you may take it when needed as long as you follow the recommended timing for your prescribed dose.

Do not take an extra dose to make up for a missed dose, and do not take Stendra more than once within 24 hours.

Do Not Take More Than Prescribed

Do not take a larger dose or use Stendra more often than your healthcare provider recommends.

Taking more medication will not necessarily improve erectile function and may increase the risk of side effects.

Tell Your Healthcare Provider About Other Medications

Before taking Stendra, tell your healthcare provider and pharmacist about all products you use, including:

  • Prescription medications
  • Over-the-counter medications
  • Vitamins
  • Supplements
  • Herbal products

Some medications can interact with Stendra and may require a lower dose or make Stendra unsafe to use.

If Stendra Does Not Work

Do not take another dose during the same 24-hour period simply because the first dose did not work as expected.

Several factors can affect how well Stendra works, including timing, food, sexual stimulation, other medications, and the underlying cause of erectile dysfunction.

If Stendra does not work well enough after several attempts, speak with your healthcare provider. Your dose or treatment plan may need to be adjusted.

Common Side Effects of Stendra (Avanafil):

Serious Side Effects of Stendra (Avanafil):

  • Difficulty breathing
  • Hives
  • Lightheadedness
  • Numbness or tingling in your chest, arms, neck, or jaw
  • Pain during erection
  • Pain, swelling, warmth, or redness in one or both legs
  • Penis erection that is painful or lasts 4 hours or longer
  • Priapism (painful, prolonged erection)
  • Ringing in your ears
  • Shortness of breath
  • Sudden hearing loss
  • Sudden vision loss
  • Swelling in your hands or feet
  • Swelling of your face, lips, tongue, or throat
  • Tinnitus
  • Vision changes

Stendra (Avanafil) is available in the following forms and strengths:

Stendra: Tablet

  • 50 mg
  • 100 mg
  • 200 mg

Avanafil: Tablet

  • 100 mg
  • 200 mg

Allergic Reactions

Do not take Stendra if you are allergic to avanafil or any other ingredient in the medication.

Seek immediate medical attention if you develop signs of a serious allergic reaction, such as:

  • Hives
  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing

Heart and Blood Vessel Problems

Stendra can lower blood pressure and affect blood flow.

Tell your healthcare provider if you have:

  • Heart disease
  • A history of heart attack
  • A history of stroke
  • Low blood pressure
  • Uncontrolled high blood pressure
  • An irregular heartbeat

Sexual activity itself can place extra strain on the heart. Your healthcare provider may need to determine whether sexual activity and Stendra are safe for you.

Nitrates

Do not take Stendra with nitrate medications.

Nitrates are commonly used to treat chest pain or angina. Combining them with Stendra can cause a dangerous drop in blood pressure.

Examples include:

  • Nitroglycerin
  • Isosorbide dinitrate
  • Isosorbide mononitrate

If you develop chest pain after taking Stendra, seek medical attention and tell the healthcare professional when you last took the medication.

Other Blood Pressure Medications

Stendra can also lower blood pressure when taken with certain alpha-blockers or other medications used to treat high blood pressure.

This may cause dizziness, lightheadedness, or fainting.

Your healthcare provider may recommend a lower starting dose if you take these medications.

Prolonged Erection

Rarely, Stendra can cause an erection that lasts too long.

Seek immediate medical attention if an erection lasts more than 4 hours.

A prolonged erection, called priapism, can permanently damage the penis if it is not treated promptly.

Sudden Vision Changes

Rare cases of sudden vision loss have been reported with PDE5 inhibitors.

Stop taking Stendra and seek medical attention immediately if you suddenly lose vision in one or both eyes.

Tell your healthcare provider if you have a history of serious eye disease or previous sudden vision loss.

Sudden Hearing Loss

Stop taking Stendra and seek medical attention if you develop sudden hearing loss or a sudden decrease in hearing.

Hearing changes may sometimes occur with:

  • Ringing in the ears
  • Dizziness

Prompt medical evaluation is important.

Alcohol

Drinking larger amounts of alcohol while taking Stendra can increase the risk of:

  • Dizziness
  • Headache
  • Faster heartbeat
  • Low blood pressure
  • Fainting

Alcohol can also make it more difficult to achieve an erection.

Ask your healthcare provider how much alcohol, if any, is appropriate while you are using Stendra.

Grapefruit and Grapefruit Juice

Grapefruit juice may increase the amount of avanafil in your body because it can affect the CYP3A4 enzyme that helps break down the medication.

This could increase the risk of side effects.

Ask your healthcare provider or pharmacist whether you should avoid grapefruit products while taking Stendra.

Drug Interactions

Stendra can interact with several medications.

Important interactions may occur with certain:

  • Antibiotics
  • Antifungal medications
  • HIV medications
  • Blood pressure medications
  • Alpha-blockers
  • Other erectile dysfunction medications

Strong CYP3A4 inhibitors, such as ketoconazole, itraconazole, ritonavir, and certain other medications, can greatly increase avanafil levels and should not be used with Stendra.

Tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, supplements, and herbal products you use.

Liver Problems

Tell your healthcare provider if you have liver disease.

People with mild or moderate liver impairment may be able to use Stendra, but it is not recommended for people with severe liver impairment.

Kidney Problems

Tell your healthcare provider if you have kidney disease.

Stendra is not recommended for people with severe kidney impairment or end-stage kidney disease requiring dialysis.

Other Erectile Dysfunction Medications

Do not combine Stendra with other PDE5 inhibitors or erectile dysfunction treatments unless your healthcare provider specifically tells you to.

Using these medications together may increase the risk of low blood pressure and other side effects.

Use in Women and Children

Stendra is approved for the treatment of erectile dysfunction in adult men.

It is not indicated for use in women, and its safety and effectiveness have not been established in children.

How long does Stendra last?

Stendra may help improve erectile function for several hours after a dose, with effects lasting up to about 6 hours in some people. This does not mean you will have an erection for 6 hours. An erection should only occur with sexual stimulation. The exact duration can vary depending on your dose, health, food intake, and other medications you take.

Is Stendra safe for everyone?

No. Stendra is not suitable for everyone. It is approved for the treatment of erectile dysfunction in adult men and is not intended for use in women or children. Stendra may also be unsafe if you take nitrate medications for chest pain, have serious heart or blood vessel disease, have very low blood pressure, have severe kidney or liver problems, take certain antibiotics, antifungal medications, or HIV medicines, or use other medications for erectile dysfunction. Tell your healthcare provider about your medical history and all medications, supplements, and herbal products you use before taking Stendra.

REVIEWS

Additional Information Book
Generic name:

Avanafil

Formulation:

Tablet

Strength(s):

50mg, 100mg, 200mg

Quantities Available:

4, 8, 12, 16, 20, 88

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Stendra can I order at once from a Canadian pharmacy?

When ordering Stendra (avanafil) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Stendra is commonly prescribed in dosages of 50 mg, 100 mg, or 200 mg, taken as needed before sexual activity, with a maximum dosage of 200 mg per day. For a 90-day supply, this means you would order up to 90 tablets (90 days x 1 tablet per day).

Do you sell avanafil?

Yes, we sell avanafil on our website. You can enjoy low prices when you order through us. To purchase avanafil, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication safely and appropriately. You have the option to submit your prescription by mailing it to us, faxing it, or uploading it through your online account.

Do you offer shipping of Stendra (avanafil) to the United States?

Yes, we ship Stendra (avanafil) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Stendra (Avanafil). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Stendra (Avanafil).