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Formulation: Extended Release Tablet
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Formulation: Extended Release Tablet
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Pristiq contains the active ingredient desvenlafaxine. It is a prescription antidepressant approved to treat major depressive disorder in adults. Pristiq is not officially approved to treat generalized anxiety disorder, although a healthcare provider may sometimes prescribe it off-label when they believe it is appropriate.
Major depressive disorder is a medical condition that affects how you feel, think, and manage everyday activities. It involves more than temporary sadness or feeling discouraged after a difficult event.
Symptoms may continue for several weeks or longer and can include a persistent low mood, loss of interest or enjoyment, low energy, changes in sleep or appetite, difficulty concentrating, feelings of guilt or worthlessness, and thoughts of death or self-harm.
Depression can affect your work, relationships, physical health, and ability to complete daily responsibilities. The symptoms and their severity can differ from one person to another.
Pristiq may help reduce depressive symptoms and improve your ability to function. As treatment begins to work, you may notice improvements in areas such as:
Not every symptom improves at the same time. Sleep, appetite, or energy may improve before your overall mood does.
Pristiq is not specifically approved for generalized anxiety disorder. However, depression and anxiety often occur together, and some people with major depressive disorder may also experience excessive worry, tension, restlessness, irritability, or difficulty sleeping.
A healthcare provider may sometimes prescribe Pristiq off-label for anxiety-related symptoms. Off-label use means that the medication is being used for a purpose that is not listed as an officially approved indication.
This does not necessarily mean the treatment is inappropriate. Healthcare providers may recommend off-label treatment after considering your symptoms, medical history, other available medications, and the possible benefits and risks.
Pristiq belongs to a group of antidepressants called serotonin-norepinephrine reuptake inhibitors, commonly known as SNRIs.
Serotonin and norepinephrine are natural chemical messengers that help nerve cells communicate in the brain. They are involved in mood, motivation, concentration, alertness, and the body’s response to stress.
After these chemicals carry a message between nerve cells, they are normally reabsorbed by the cell that released them. This process is called reuptake.
Pristiq reduces the reuptake of serotonin and norepinephrine. This increases their activity between nerve cells and may help improve communication in areas of the brain involved in mood regulation. The exact way this produces an antidepressant effect is not fully understood.
Pristiq does not usually provide immediate relief. Some symptoms may begin to improve during the first few weeks, but it may take several weeks to experience a fuller antidepressant effect.
Your response will depend on factors such as the severity of your depression, your individual health, and how consistently you take the medication. Clinical studies supporting its effectiveness in adults generally assessed treatment over approximately eight weeks.
Continue taking Pristiq exactly as prescribed, even if you do not notice an immediate improvement. Speak with your healthcare provider if your symptoms do not improve, become worse, or interfere more significantly with your daily life.
Pristiq helps manage the symptoms of depression, but it does not permanently cure the condition. Some people may need treatment for several months or longer to help prevent symptoms from returning.
Medication may be one part of a broader treatment plan. Depending on your needs, your healthcare provider may also recommend counselling, psychotherapy, regular physical activity, healthy sleep habits, social support, and treatment for other medical or mental health conditions.
Pristiq should only be used under the supervision of a healthcare provider. Do not change your dose or stop taking it suddenly without medical guidance.
Pristiq is an extended-release tablet that you take by mouth. It is usually taken once a day, with or without food.
Extended-release means that the tablet releases the medication slowly throughout the day. This helps maintain a steady amount of desvenlafaxine in your body.
Swallow the tablet whole with water. Do not crush, chew, split, cut, or dissolve it.
Damaging the tablet may interfere with the extended-release system and cause the medication to be released too quickly. This may increase the risk of side effects.
Take Pristiq at approximately the same time every day. You may take it in the morning or evening, but try to follow the same schedule each day. Taking it regularly helps keep the medication level consistent and may help you remember each dose.
You may take Pristiq with or without food. If the medication causes nausea or stomach discomfort, taking it with food may make it easier to tolerate.
The usual recommended dose of Pristiq for adults with major depressive disorder is 50 mg once daily.
Clinical studies have shown that doses from 50 mg to 100 mg daily can be effective. However, doses above 50 mg have not generally been shown to provide additional benefit for most patients. Higher doses may also increase the risk of side effects.
Your healthcare provider will determine the most appropriate dose based on:
Do not increase your dose on your own. Taking a higher dose will not necessarily make Pristiq work faster or better.
Some people may need a lower dose or a different dosing schedule, particularly those with kidney problems. Your healthcare provider may review your kidney function before or during treatment.
Your dose may also be adjusted if you experience side effects or if your symptoms do not improve. Follow all instructions carefully when your dose changes.
Pristiq does not usually improve depression immediately. Some symptoms, such as sleep, appetite, energy, or concentration, may begin to improve within the first few weeks.
It may take several weeks before you notice a fuller improvement in your mood, interest in activities, or ability to manage daily tasks.
Continue taking Pristiq as prescribed, even if you do not feel better right away. Contact your healthcare provider if your symptoms do not improve, become worse, or you develop new or concerning changes in mood or behaviour.
Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule.
Do not take two doses at the same time to make up for a missed dose. Taking extra Pristiq may increase the risk of side effects.
Do not stop taking Pristiq without speaking with your healthcare provider. Suddenly stopping the medication can cause withdrawal symptoms, also called discontinuation symptoms.
These may include:
Your healthcare provider may gradually reduce your dose over time. This process is called tapering and can help reduce the risk of withdrawal symptoms.
Take Pristiq exactly as prescribed. Do not take more tablets, use the medication more often, or continue treatment longer than directed.
You may occasionally notice what looks like a tablet shell in your stool. This can occur because the empty outer shell may pass through your digestive system after the medication has been released. It does not usually mean that your body failed to absorb the dose.
Contact your healthcare provider or pharmacist if you are unsure about your dose, tablet strength, dosing time, missed doses, or how to stop treatment safely.
Pristiq (Desvenlafaxine) is available in the following forms and strengths:
Do not take Pristiq with a monoamine oxidase inhibitor, also called an MAOI. Combining these medications can cause a serious and potentially life-threatening reaction.
You should not start Pristiq within 14 days after stopping an MAOI. You should also wait at least 7 days after stopping Pristiq before starting an MAOI. Examples include isocarboxazid, phenelzine, selegiline, and tranylcypromine. Certain medications, such as linezolid and intravenous methylene blue, can also act like MAOIs and may cause a dangerous interaction.
Always tell your healthcare provider and pharmacist that you take Pristiq before starting an antibiotic, receiving an injection, or taking another medication.
Do not stop taking Pristiq or change your dose without speaking with your healthcare provider. Stopping the medication suddenly may cause withdrawal symptoms and may allow your depression to return or become worse.
Withdrawal symptoms may include dizziness, nausea, headache, irritability, anxiety, sweating, trouble sleeping, unusual dreams, flu-like symptoms, or electric-shock-like sensations.
Your healthcare provider may gradually reduce your dose over time to help lower the risk of these symptoms.
Depression and other mental health conditions can sometimes cause thoughts of suicide or self-harm. In some people, these thoughts may appear or become worse when antidepressant treatment begins or when the dose changes. The risk may be higher in children, teenagers, and young adults.
Contact your healthcare provider immediately if you or someone close to you notices new or sudden changes such as:
Seek emergency help if you believe you may act on thoughts of harming yourself.
Do not take Pristiq if you are allergic to desvenlafaxine, venlafaxine, or any ingredient in the medication. Desvenlafaxine is closely related to venlafaxine, so an allergy to one may increase the risk of reacting to the other.
Tell your healthcare provider about all medication allergies and previous adverse reactions before beginning treatment.
Stop taking the medication and seek immediate medical attention if you develop swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, severe dizziness, hives, or a widespread rash.
Pristiq may increase your risk of bruising or bleeding. The risk may be greater if you also take medications that affect blood clotting, such as aspirin, ibuprofen, naproxen, warfarin, apixaban, rivaroxaban, clopidogrel, or other blood thinners.
Tell your healthcare provider if you have a bleeding disorder, a history of stomach ulcers, or unusual bleeding.
Contact your healthcare provider if you notice frequent nosebleeds, unexplained bruising, bleeding gums, blood in your urine, black stools, or bleeding that takes longer than usual to stop.
Pristiq may raise your blood pressure and heart rate. Your healthcare provider may check your blood pressure before treatment and regularly while you are taking the medication.
Tell your healthcare provider if you have high blood pressure, heart disease, or an irregular heartbeat. Contact them if you develop a severe headache, chest pain, a pounding heartbeat, shortness of breath, or significant dizziness.
Pristiq increases serotonin activity in the brain. Taking it with other medications or supplements that also increase serotonin may cause serotonin syndrome, a rare but potentially life-threatening condition.
Medications that may increase this risk include other antidepressants, MAOIs, certain migraine medications, some opioid pain medicines, lithium, buspirone, amphetamines, and the herbal supplement St. John’s wort.
Seek immediate medical attention if you develop agitation, confusion, hallucinations, fever, heavy sweating, a fast heartbeat, muscle stiffness, shaking, poor coordination, nausea, vomiting, or diarrhea.
Tell your healthcare provider if you have kidney or liver disease. These conditions may affect how your body processes and removes Pristiq.
People with kidney problems may need a lower dose or a different dosing schedule. Your healthcare provider will determine the safest dose based on your kidney and liver function.
Older adults may be more sensitive to side effects such as dizziness, low sodium levels, bleeding, or changes in blood pressure. These effects may increase the risk of confusion, weakness, or falls.
Tell your healthcare provider if you have glaucoma, seizures, high blood pressure, bipolar disorder, low sodium levels, or a history of bleeding problems before taking Pristiq.
Pristiq may increase pressure inside the eye in people with narrow-angle glaucoma. It may also increase the risk of seizures in susceptible patients. Your healthcare provider will determine whether additional monitoring or another treatment is needed.
Desvenlafaxine does not usually improve depression immediately. Some symptoms, such as sleep, appetite, energy, or concentration, may begin to improve within the first few weeks. However, it may take several weeks before you notice a fuller improvement in your mood or interest in daily activities. Continue taking the medication exactly as prescribed, even if you do not feel better right away. Contact your healthcare provider if your symptoms become worse, do not improve after several weeks, or you develop new or concerning changes in your mood or behaviour.
Desvenlafaxine can interact with certain medications, vitamins, and herbal supplements. Before starting treatment, tell your healthcare provider and pharmacist about everything you take. Possible interactions may occur with other antidepressants, MAO inhibitors, blood thinners, anti-inflammatory pain relievers, certain migraine medications, some opioid pain medicines, lithium, stimulants, and St. John’s wort. These combinations may increase the risk of bleeding, serotonin syndrome, high blood pressure, or other side effects. Do not start, stop, or change another medication without first speaking with your healthcare provider or pharmacist.
It is best to avoid alcohol while taking desvenlafaxine. Alcohol may worsen dizziness, drowsiness, poor coordination, impaired judgment, or symptoms of depression. It may also make some side effects more difficult to manage. Speak with your healthcare provider if you drink alcohol regularly or have questions about whether any amount is safe for you.
Tell your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Desvenlafaxine may sometimes be used during pregnancy when the expected benefits outweigh the possible risks. Taking the medication later in pregnancy may affect the newborn and could cause temporary symptoms after birth. However, untreated depression can also create risks for both the pregnant patient and the baby. Do not stop taking desvenlafaxine suddenly if you become pregnant. Desvenlafaxine can pass into breast milk. Your healthcare provider will consider the benefits of breastfeeding, the importance of treatment, and the possible effects on the nursing baby before recommending whether you should continue the medication.
Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. Taking extra desvenlafaxine may increase the risk of side effects. Contact your healthcare provider or pharmacist if you are unsure what to do after missing a dose.
| Generic name: | Desvenlafaxine |
|---|---|
| Formulation: | Extended Release Tablet |
| Strength(s): | 25mg, 50mg, 100mg |
| Quantities Available: | 28, 30, 84, 90, 100 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Pristiq (desvenlafaxine) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Pristiq is commonly prescribed in dosages of 25 mg, 50 mg or 100 mg, taken once daily. For a 90-day supply, you would order 90 tablets (90 days x 1 tablet per day).
Yes, we sell desvenlafaxine on our website, and you can enjoy low prices. To purchase desvenlafaxine, you will need a valid prescription from your healthcare provider. We require this to dispense the medication. You can conveniently submit your prescription by mail, fax, or upload it through your online account to facilitate the ordering process.
Yes, we ship Pristiq (desvenlafaxine) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Pristiq (Desvenlafaxine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Pristiq (Desvenlafaxine).
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