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Formulation: Tablet
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Parnate (active ingredient: tranylcypromine) is a prescription antidepressant used to treat major depressive disorder in adults.
It belongs to a group of medications called monoamine oxidase inhibitors (MAOIs). These medicines are usually considered when other antidepressant treatments have not worked well enough.
Parnate may be used to treat major depressive episodes in adults.
Depression can affect mood, energy, sleep, concentration, appetite, and interest in daily activities. Symptoms may include:
Parnate may help improve these symptoms over time.
Parnate is often used for depression that has not improved enough with other antidepressants.
This may include people who have tried other types of antidepressant medications without getting adequate symptom relief.
Because MAOIs have important food and drug interactions, Parnate is usually prescribed only after a healthcare provider has carefully reviewed other treatment options.
Parnate works by blocking an enzyme called monoamine oxidase.
This enzyme normally breaks down certain chemical messengers in the brain, including:
By blocking monoamine oxidase, Parnate allows more of these neurotransmitters to remain available in the brain.
These chemicals play important roles in mood, motivation, emotional responses, and other brain functions.
Increasing the activity of serotonin, norepinephrine, and dopamine may help improve communication between nerve cells involved in mood regulation.
Over time, this may help:
Parnate has important interactions with certain medications, supplements, and foods high in tyramine.
These interactions can sometimes cause serious reactions, including dangerously high blood pressure.
For this reason, follow your healthcare provider’s instructions carefully and make sure they know about all medications, supplements, and over-the-counter products you use.
Parnate is available as a tablet taken by mouth.
It is usually taken in divided doses during the day, although your healthcare provider will tell you exactly when and how often to take it.
Parnate may be taken with or without food.
A common starting dose is 30 mg per day, usually divided into smaller doses.
Your healthcare provider may begin with a lower dose and gradually increase it depending on how well your symptoms improve and whether you experience side effects.
The maximum recommended dose is generally 60 mg per day, usually divided into multiple doses.
Do not take more than the amount prescribed by your healthcare provider.
Your healthcare provider may change your dose based on:
Once your symptoms improve, your healthcare provider may adjust your dose to the lowest amount that continues to control your symptoms.
Take Parnate at approximately the same times each day.
Following a regular schedule helps maintain consistent medication levels and may make it easier to remember your doses.
Take Parnate exactly as directed.
Do not:
Taking more Parnate than prescribed can increase the risk of serious side effects.
Do not stop taking Parnate without speaking with your healthcare provider first.
Stopping the medication suddenly may cause withdrawal symptoms or allow depression symptoms to return.
If treatment needs to be stopped, your healthcare provider may gradually reduce your dose.
Because Parnate can sometimes cause difficulty sleeping, your healthcare provider may recommend taking later doses earlier in the day rather than close to bedtime.
Follow the dosing schedule provided by your healthcare provider.
While taking Parnate, you must avoid certain high-tyramine foods and medications because serious interactions can occur.
Some combinations may cause a dangerous increase in blood pressure or other severe reactions.
Before starting any new prescription medication, over-the-counter medicine, supplement, or herbal product, check with your healthcare provider or pharmacist.
Parnate (Tranylcypromine) is available in the following forms and strength:
Parnate can interact with certain foods, prescription medications, over-the-counter medicines, and supplements.
Some combinations can cause a dangerous rise in blood pressure or other serious reactions. This is especially important with certain cough and cold medicines, decongestants, stimulants, antidepressants, and foods high in tyramine.
Always check with your healthcare provider or pharmacist before starting any new medicine or supplement while taking Parnate.
Parnate may increase the risk of suicidal thoughts or behavior in some people, especially when treatment is first started or when the dose is changed.
Contact your healthcare provider right away if you notice worsening depression, unusual changes in mood or behavior, or thoughts of self-harm.
Parnate can cause a serious condition called serotonin syndrome when it is combined with certain medications that increase serotonin.
This risk is especially important with some antidepressants, including SSRIs and other serotonergic medications.
Possible symptoms may include:
Seek immediate medical attention if these symptoms occur.
Parnate can cause a hypertensive crisis, which is a sudden and dangerous increase in blood pressure.
This may happen if you eat foods that are high in tyramine, take certain interacting medications, or take more Parnate than prescribed.
Possible warning signs include:
Seek emergency medical care if you develop symptoms of a hypertensive crisis.
Parnate may not be appropriate for people with certain heart or blood pressure conditions.
Tell your healthcare provider if you have a history of heart disease, uncontrolled high blood pressure, or stroke before starting treatment.
Parnate should be used carefully in people with liver disease.
Your healthcare provider may need to review your liver function before or during treatment.
Older adults may be more sensitive to some of the effects of Parnate.
They may have a higher risk of:
Closer monitoring may be needed.
If you are pregnant, planning to become pregnant, or think you may be pregnant, talk to your healthcare provider before taking Parnate.
Your provider will weigh the possible benefits of treatment against any potential risks.
Talk to your healthcare provider before taking Parnate if you are breastfeeding.
Your provider can help determine whether Parnate is appropriate or whether another treatment would be preferred.
Parnate may take several weeks to provide its full antidepressant effect. Some symptoms may improve earlier, but changes in mood, motivation, and interest in daily activities can take longer. Continue taking Parnate exactly as prescribed and tell your healthcare provider if your symptoms are not improving or become worse.
Parnate is mainly used to treat major depressive disorder, especially when other antidepressants have not worked well enough. In some cases, a healthcare provider may prescribe tranylcypromine for another condition. These uses are considered off-label and should only be considered under specialist supervision.
No. Parnate is not suitable for everyone. It may not be appropriate for people with certain medical conditions, such as significant heart disease, uncontrolled high blood pressure, certain liver problems, or a history of stroke. Parnate can also have serious interactions with certain medications, including some antidepressants, decongestants, stimulants, and opioid pain medications. Always give your healthcare provider a complete list of everything you take before starting treatment.
If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your usual schedule. Do not take two doses at the same time or take extra tablets to make up for a missed dose.
If you are pregnant, planning to become pregnant, or breastfeeding, talk to your healthcare provider before taking Parnate. The safety of Parnate during pregnancy and breastfeeding is not fully established. Your healthcare provider will weigh the potential benefits of treatment against any possible risks before deciding whether it is appropriate for you.
| Generic name: | Tranylcypromine |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 10mg |
| Quantities Available: | 100 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Parnate (tranylcypromine) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Parnate is available in 10 mg tablet and is commonly prescribed in dosages that may vary, typically ranging from 10 mg to 60 mg per day for adults treating depression.
For example, if prescribed 30 mg per day, then for a 90-day supply, you would order 270 tablets (90 days x 3 tablets per day).
No, we do not sell tranylcypromine on our website. However, you can still enjoy low prices on Parnate, which contains tranylcypromine as an active ingredient. To purchase Parnate, you will need a valid prescription from your healthcare provider. We require this prescription to dispense the medication. You can conveniently submit your prescription by mail, fax, or upload it through your online account.
Yes, we ship Parnate (tranylcypromine) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Parnate (Tranylcypromine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Parnate (Tranylcypromine).
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