Prozac DR (Fluoxetine Delayed Release)

Indications

Prozac DR is a delayed-release form of the medication fluoxetine. It is typically used to treat depression and other mental health conditions, such as panic disorder. The delayed-release form of fluoxetine is designed to slowly release the medication over time, which can help to reduce side effects and improve treatment outcomes.

Fluoxetine works by helping to restore the balance of certain natural substances in the brain called neurotransmitters, such as serotonin. It may decrease anxiety, improve mood, sleep, appetite, and energy levels, and may help restore interest in daily living.

Use and Dosage

Fluoxetine comes as Delayed Release Capsule to take by mouth as directed by your doctor, usually once a week with or without food. Swallow the capsule whole. Do not crush or chew the contents of the capsule. Start taking it 7 days after your last dose of the form of fluoxetine that is taken daily.

The dosage is based on your medical condition and response to treatment. Use it regularly to get the most benefit from it. To help you remember, take it on the same day of the week. Mark a calendar to help you remember when you should take your next dose.

Keep taking it even if you feel well. Do not stop taking the capsules without first consulting your doctor. Some conditions may become worse when the drug is abruptly stopped. Your dose may need to be gradually decreased.

If you miss a dose of Prozac DR, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double up on doses to make up for a missed one.

Side Effects

Common Side Effects of Prozac DR (Fluoxetine Delayed Release):

• Anxiety
• Confusion
• Diarrhea
• Difficulty concentrating or memory problems
• Difficulty falling asleep or staying asleep
• Dry mouth
• Excessive sweating
• Headache
• Heartburn
• Loss of appetite
• Nausea
• Nervousness
• Sexual problems in females; decreased sex drive, or delayed orgasm or unable to have an orgasm
• Sexual problems in males; decreased sex drive, inability to get or keep an erection, or delayed or absent ejaculation
• Stuffy nose
• Uncontrollable shaking of a part of the body
• Unusual dreams
• Weakness
• Weight loss
• Yawning

Serious Side Effects of Prozac DR (Fluoxetine Delayed Release):

• Abnormal bleeding or bruising
• Agitation, fever, sweating, confusion, fast or irregular heartbeat, shivering, severe muscle stiffness or twitching, hallucinations, loss of coordination, nausea, vomiting, or diarrhea
• Difficulty breathing or swallowing
• Dizziness or fainting
• Fast, slow, or irregular heartbeat
• Fever
• Hives or blisters
• Itching
• Joint pain
• Rash
• Seizures
• Shortness of breath
• Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

Forms and Strength

Prozac DR (Fluoxetine Delayed Release) is available in the following forms and strength:

Fluoxetine Delayed Release: Capsule

• 90 mg

Cautions

• Suicidal thoughts or behavior: There is a warning about the increased risk of suicidal thoughts and behavior, particularly in children, teenagers, and young adults that should be closely monitored.
• Serotonin syndrome: There is a risk of developing a serious condition called serotonin syndrome, which can cause symptoms such as agitation, hallucinations, muscle stiffness, rapid heart rate, sweating, and fever, especially when used in combination with other medications.
• Worsening depression and anxiety: Fluoxetine may cause worsening of symptoms or the emergence of new symptoms of depression, anxiety, or other mental health conditions.
• Seizures: Fluoxetine may cause seizures, especially in those with a history of seizures or other risk factors.
• Bleeding: Fluoxetine may increase the risk of bleeding, especially when used with other medications that affect blood clotting.
• Allergic reactions: Fluoxetine may cause allergic reactions in some people, which can be serious.
• Mania or hypomania: Fluoxetine may cause manic or hypomanic episodes in people with bipolar disorder.
• Seizures: Fluoxetine may lower the seizure threshold and cause seizures, especially in those with a history of seizures or other risk factors.
• Diabetes: Fluoxetine may affect blood sugar levels and may worsen diabetes symptoms in some people.
• Bone health: Long-term use of Prozac DR may increase the risk of bone fractures, particularly in older adults.
• Pregnancy and breastfeeding: Fluoxetine may harm an unborn baby, and it can pass into breast milk and harm a nursing infant. Discuss the risks and benefits of taking fluoxetine during pregnancy or while breastfeeding with a healthcare provider.
• Drug interactions: Fluoxetine may interact with other medications, including prescription and over-the-counter drugs, herbal supplements, and vitamins. Discuss all medications and supplements you are taking with your healthcare provider before starting fluoxetine.

Frequently Asked Questions (FAQ)

How long does it take for Prozac DR to start working?

It may take several weeks for Prozac DR to start working, and the full effects of the medication may not be felt for several months.

Can Prozac DR be stopped abruptly?

Sudden discontinuation of Prozac DR may lead to withdrawal symptoms, such as headache, nausea, vomiting, dizziness, and irritability.

Can Prozac DR be addictive?

Prozac DR is not considered addictive. However, sudden discontinuation of the medication may lead to withdrawal symptoms.

Resources

• https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018936s091lbl.pdf
• https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=887fc670-db67-4cfe-967b-46b38375dae5
• https://www.webmd.com/drugs/2/drug-1774-5095/fluoxetine-oral/fluoxetine-enteric-coated-oral/details
• https://www.webmd.com/drugs/2/drug-6997/prozac-oral/details
• https://www.goodrx.com/prozac/what-is
• https://medlineplus.gov/druginfo/meds/a689006.html