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Edarbyclor (Azilsartan Medoxomil/Chlorthalidone) Shopper Approved

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Edarbyclor

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Prescription Prescription Required FormationFormulation: Tablet

Azilsartan Medoxomil/Chlorthalidone

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Edarbyclor contains azilsartan medoxomil and chlorthalidone. It is a prescription medication used to treat high blood pressure, also called hypertension.

It may be prescribed when one blood pressure medicine is not enough or when a healthcare provider believes that treatment with both an ARB and a diuretic is appropriate.

What is High Blood Pressure?

High blood pressure happens when the force of blood pushing against the walls of your arteries stays too high over time.

Many people with hypertension do not notice any symptoms. Even so, uncontrolled high blood pressure can gradually damage the heart, blood vessels, kidneys, and other organs.

Keeping blood pressure within a healthier range can reduce the risk of serious complications such as stroke and heart attack.

How Does Azilsartan Medoxomil Work?

Azilsartan medoxomil belongs to a group of medicines called angiotensin II receptor blockers, or ARBs.

Angiotensin II is a natural substance in the body that causes blood vessels to tighten. When blood vessels become narrow, blood pressure can rise.

Azilsartan blocks the effects of angiotensin II. This allows the blood vessels to relax and widen, making it easier for blood to flow and helping lower blood pressure.

How Does Chlorthalidone Work?

Chlorthalidone is a thiazide-like diuretic, sometimes called a water pill.

It helps the kidneys remove extra sodium and water from the body through urine. Reducing excess fluid can lower the amount of fluid circulating in the bloodstream, which helps lower blood pressure.

Because chlorthalidone increases urination, some people may notice that they need to urinate more often, especially after taking a dose.

Why Are These Two Medicines Combined?

Azilsartan and chlorthalidone lower blood pressure in different ways.

Azilsartan helps relax blood vessels, while chlorthalidone helps the body remove extra salt and water.

Using these two effects together can provide stronger blood pressure control than either medicine may provide alone for some people.

Can Edarbyclor Be Used as a First Treatment?

Edarbyclor may be considered when a healthcare provider believes that a person is likely to need more than one medicine to reach their blood pressure goal.

It can also be used when blood pressure is not adequately controlled with either azilsartan or chlorthalidone alone.

Your healthcare provider will choose treatment based on your blood pressure readings, medical history, kidney function, electrolyte levels, and other medicines you take.

Does Edarbyclor Cure High Blood Pressure?

No. Edarbyclor helps control hypertension, but it does not permanently cure it.

You may need to continue taking the medication even after your blood pressure improves. Do not stop treatment on your own, because your blood pressure may rise again.

How Will I Know if Edarbyclor is Working?

High blood pressure often causes no symptoms, so you may not feel different even when the medication is working.

Regular blood pressure checks are the best way to see how well treatment is controlling your blood pressure.

Your healthcare provider may ask you to monitor your blood pressure at home and bring your readings to follow-up appointments.

Why Are Blood Tests Sometimes Needed?

Edarbyclor can affect kidney function, potassium, sodium, and fluid balance.

Your healthcare provider may order blood tests before and during treatment to make sure your kidneys are working properly and your electrolyte levels remain within a safe range.

What Else Can Help Lower Blood Pressure?

Medication often works best when combined with healthy lifestyle habits.

Your healthcare provider may recommend reducing excess sodium, staying physically active, maintaining a healthy weight, and following a heart-healthy eating plan.

These changes can support the blood pressure-lowering effects of Edarbyclor.

Important Pregnancy Warning

Edarbyclor should not be used during pregnancy because azilsartan can cause serious harm to a developing baby.

If you become pregnant while taking Edarbyclor, contact your healthcare provider promptly so your treatment can be changed.

Important Reminder

Edarbyclor combines azilsartan medoxomil, an ARB, with chlorthalidone, a thiazide-like diuretic. Together, they help lower blood pressure by relaxing blood vessels and helping the body remove extra sodium and water.

Take Edarbyclor exactly as prescribed, continue monitoring your blood pressure, and attend any recommended blood tests so your healthcare provider can make sure the treatment remains safe and effective.

Edarbyclor contains azilsartan medoxomil and chlorthalidone and is taken by mouth to help lower high blood pressure. It is usually taken once daily, with or without food.

Take Edarbyclor exactly as prescribed by your healthcare provider. Try to take it at about the same time every day so it becomes part of your regular routine.

Recommended Starting Dose

The usual starting dose is 40 mg/12.5 mg once daily.

This means each tablet contains:

  • 40 mg of azilsartan medoxomil
  • 12.5 mg of chlorthalidone

Your healthcare provider may choose this dose when one blood pressure medicine is not enough or when you are likely to need more than one medicine to reach your blood pressure goal.

Increasing the Dose

Most of the blood pressure-lowering effect becomes noticeable within about 1 to 2 weeks.

If your blood pressure is still higher than your target, your healthcare provider may increase the dose after 2 to 4 weeks to 40 mg/25 mg once daily. This is the maximum recommended dose.

Do not increase the dose on your own, even if your home blood pressure readings remain high.

Can Edarbyclor Be Taken With Food?

Yes. Edarbyclor can be taken with or without food.

Choose a routine that is easy for you to follow consistently. Taking it at the same time each day may make it easier to remember.

When is the Best Time to Take Edarbyclor?

Because chlorthalidone is a diuretic, or water pill, it can increase urination.

Many people find it more convenient to take Edarbyclor earlier in the day so they are less likely to wake up at night to use the bathroom. However, the official prescribing information does not require a specific time of day, so follow your healthcare provider’s instructions.

Why Does Edarbyclor Increase Urination?

Chlorthalidone helps the kidneys remove extra sodium and water from the body.

You may notice more frequent urination after taking your medication, especially when you first start treatment. This effect helps reduce fluid volume and contributes to lowering blood pressure.

Take Edarbyclor Every Day

Continue taking Edarbyclor even if you feel well.

High blood pressure often causes no noticeable symptoms, so you may not feel different even when the medication is working.

Do not stop taking Edarbyclor without speaking with your healthcare provider because your blood pressure may rise again.

How Will You Know if the Medication is Working?

Regular blood pressure checks are the best way to tell whether Edarbyclor is working.

Your healthcare provider may ask you to monitor your blood pressure at home. Keep a record of your readings and share them during follow-up appointments.

Do not take an extra tablet if one reading is higher than usual.

If You Are Dehydrated

Edarbyclor can cause blood pressure to drop too low in people who have lost a significant amount of fluid or salt.

Tell your healthcare provider if you have had severe vomiting, diarrhea, heavy sweating, or dehydration, particularly before starting treatment. The prescribing information recommends correcting significant fluid depletion before Edarbyclor is started.

Blood Tests During Treatment

Edarbyclor can affect kidney function and electrolyte levels, including sodium and potassium.

Your healthcare provider may order blood tests during treatment to check that your kidneys are working properly and your electrolyte levels remain within a safe range.

What If You Miss a Dose?

If you forget to take Edarbyclor, the current patient instructions say to take the missed dose later that same day when you remember.

If you do not remember until the next day, skip the missed dose and continue your normal schedule. Do not double your dose the following day.

Can Edarbyclor Be Taken With Other Blood Pressure Medicines?

Yes. Edarbyclor may be used with other blood pressure medicines when additional control is needed.

Your healthcare provider may monitor you more closely because combining blood pressure medicines can sometimes cause dizziness or blood pressure that becomes too low.

What If You Feel Dizzy?

Dizziness can occur, particularly when you first begin treatment or if your blood pressure becomes too low.

Stand up slowly after sitting or lying down. Contact your healthcare provider if you have repeated dizziness, weakness, or fainting.

Pregnancy Warning

Edarbyclor can cause serious harm to a developing baby because it contains azilsartan, an ARB.

If you become pregnant while taking Edarbyclor, contact your healthcare provider promptly so your blood pressure treatment can be changed.

How Should Edarbyclor Be Stored?

Store Edarbyclor at room temperature and keep it in its original container, tightly closed and protected from light and moisture. The prescribing information specifically advises against repackaging the tablets.

Important Reminder

The usual starting dose of Edarbyclor is 40 mg/12.5 mg once daily. If additional blood pressure control is needed, your healthcare provider may increase the dose after 2 to 4 weeks to 40 mg/25 mg once daily, which is the maximum recommended dose.

Take Edarbyclor consistently, continue checking your blood pressure as recommended, and do not change your dose without speaking with your healthcare provider.

Common Side Effects of Edarbyclor (Azilsartan Medoxomil/Chlorthalidone):

  • Dizziness
  • Nausea
  • Vomiting
  • Fatigue
  • Headache
  • Diarrhea

Serious Side Effects of Edarbyclor (Azilsartan Medoxomil/Chlorthalidone):

  • Blurred vision
  • Confusion
  • Convulsions
  • Decreased urine
  • Faintness
  • Lightheadedness
  • Dry mouth
  • Fainting
  • Increased thirst
  • Irregular heartbeat
  • Loss of appetite
  • Muscle pain or cramps
  • Numbness or tingling in the hands, feet, or lips
  • Shortness of breath
  • Sweating
  • Unusual tiredness or weakness

Edarbyclor (Azilsartan Medoxomil/Chlorthalidone) is available in the following forms and strength:

Edarbyclor: Tablet

  • 40/25 mg
  • 40/12.5 mg

Azilsartan Medoxomil/Chlorthalidone: Tablet

  • 40/25 mg

Low Blood Pressure and Dizziness

Edarbyclor can sometimes cause your blood pressure to become too low, especially if you are dehydrated or have lost too much salt or fluid.

Signs may include dizziness, lightheadedness, weakness, or fainting. If you feel dizzy, sit or lie down until you feel better. If you faint, stop taking Edarbyclor and seek medical attention.

Kidney Problems

Edarbyclor can sometimes worsen kidney function, especially in people who already have kidney disease, renal artery narrowing, severe heart failure, or dehydration.

Your healthcare provider may order blood tests to monitor your kidneys. Contact them if you notice a significant decrease in urination or other unusual symptoms.

Electrolyte Changes

Because Edarbyclor contains chlorthalidone, it can affect important electrolytes such as sodium and potassium.

Your healthcare provider may periodically check your electrolyte levels with blood tests. Tell them if you develop unusual weakness, muscle cramps, confusion, or an irregular heartbeat.

Pregnancy Warning

Edarbyclor can cause serious harm to a developing baby and should not be used during pregnancy.

If you become pregnant while taking Edarbyclor, contact your healthcare provider promptly. The current prescribing information recommends stopping Edarbyclor as soon as pregnancy is detected.

Medication and Supplement Interactions

Before starting Edarbyclor, tell your healthcare provider about all prescription medicines, over-the-counter products, vitamins, and supplements you take.

Certain medicines can increase the risk of kidney problems, low blood pressure, or abnormal potassium levels. Lithium also requires special monitoring when used with Edarbyclor.

Blood Pressure Monitoring

Check your blood pressure as recommended by your healthcare provider. Regular monitoring helps show whether Edarbyclor is controlling your hypertension without lowering your blood pressure too much.

Blood tests may also be needed to monitor kidney function and electrolyte levels during treatment.

Driving and Operating Machinery

Edarbyclor may cause dizziness or lightheadedness, especially when treatment is first started or if your blood pressure drops too low.

Until you know how the medication affects you, use caution when driving, operating machinery, or doing other activities that require steady balance and alertness.

Dehydration

Vomiting, diarrhea, heavy sweating, or not drinking enough fluids can lead to dehydration and make your blood pressure drop too much while taking Edarbyclor.

Contact your healthcare provider if you develop significant vomiting, diarrhea, or dehydration. Do not automatically increase your fluid intake if you have been told to limit fluids because of another medical condition.

Do Not Stop or Change Treatment on Your Own

Take Edarbyclor exactly as prescribed. Do not routinely stop the medication or change your dose without first speaking with your healthcare provider.

However, if you faint, current patient instructions advise stopping Edarbyclor and having someone contact your healthcare provider or seek medical help.

Important Reminder

Edarbyclor can affect blood pressure, kidney function, fluid balance, sodium, and potassium levels. Keep your follow-up appointments and complete any recommended blood tests.

Tell your healthcare provider promptly if you experience fainting, severe dizziness, a major decrease in urination, or symptoms that may suggest an electrolyte problem.

Can I Take Edarbyclor During Pregnancy or Breastfeeding?

Edarbyclor should not be used during pregnancy because azilsartan can cause serious harm to a developing baby. If you become pregnant while taking Edarbyclor, contact your healthcare provider promptly so your blood pressure treatment can be changed. If you are breastfeeding or planning to breastfeed, talk to your healthcare provider before taking Edarbyclor. They can help decide whether another blood pressure medicine may be more appropriate.

Can I Drink Alcohol While Taking Edarbyclor?

Alcohol can increase side effects such as dizziness, lightheadedness, and low blood pressure. Ask your healthcare provider whether it is safe for you to drink alcohol while taking Edarbyclor, and avoid excessive alcohol use.

Can Children Take Edarbyclor?

Edarbyclor is approved for the treatment of high blood pressure in adults. Its safety and effectiveness have not been established in children. A healthcare provider should choose an age-appropriate blood pressure treatment if medication is needed for a child.

How Long Does Edarbyclor Stay in Your System?

Azilsartan, one of the active medicines in Edarbyclor, has an elimination half-life of about 12 hours. This means the amount of medicine in the body decreases by about half over that period. Chlorthalidone stays in the body much longer, with a half-life of roughly 40 to 60 hours. Because the two ingredients leave the body at different rates, some effects of Edarbyclor may continue after the last dose. The exact amount of time the medicine remains in your body can vary depending on factors such as kidney function, age, and overall health.

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Additional Information Book
Generic name:

Azilsartan Medoxomil/Chlorthalidone

Formulation:

Tablet

Strength(s):

40/12.5mg, 40/25mg

Quantities Available:

28, 56, 84, 100

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Edarbyclor can I order at once from a Canadian pharmacy?

When ordering Edarbyclor (azilsartan medoxomil/chlorthalidone) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Edarbyclor is commonly prescribed in dosages of 40/12.5mg or 40/25 mg (azilsartan medoxomil/chlorthalidone) once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).

Do you sell azilsartan medoxomil/chlorthalidone?

Yes, we sell azilsartan medoxomil/chlorthalidone on our website! You can enjoy competitive prices on this medication by ordering from us. To place an order, you will need a valid prescription from your healthcare provider. We require this to ensure the safe and accurate dispensing of medications. You can conveniently submit your prescription by mail, fax, or by uploading it through your online account.

Do you offer shipping of Edarbyclor (azilsartan medoxomil/chlorthalidone) to the United States?

Yes, we ship Edarbyclor (azilsartan medoxomil/chlorthalidone) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Edarbyclor (Azilsartan Medoxomil/Chlorthalidone). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Edarbyclor (Azilsartan Medoxomil/Chlorthalidone).