Ziana (Clindamycin Phosphate/Tretinoin)

Prescription Prescription Required     Customer Reviews
Ziana Brand
Dosage Quantity & Price
Clindamycin Phosphate/Tretinoin (Generic alternate to Ziana) Generic

We don't sell this generic-version medication.

  • We are Certified
  • Cipa Certified Canadian
  • Norton Shopping Guarantee
  • 5 Star Excellence award from Shopper Approved for collecting at least 100 5 star reviews

Table of contents:

Biacna topical gel is a prescription medication used to treat severe acne in adults and children over the age of 12. It decreases the number and severity of acne pimples and helps existing pimples to heal more quickly. It contains a combination of clindamycin phosphate and tretinoin.

Tretinoin belongs to a class of medications called retinoids. It works by affecting the growth of skin cells. Clindamycin is an antibiotic that stops the growth of bacteria that cause acne.

Biacna topical gel helps decrease the number and severity of acne pimples and helps pimples that do develop to heal more quickly. The medication can take several weeks to months to improve acne and may appear to worsen acne during the initial few weeks of use.

Use and Dosage

Biacna Topical Gel is applied topically to the affected areas of the skin once a day at bedtime, or as directed by your doctor. When using Biacna Topical Gel, first wash your hands. Next, use a mild/soapless cleanser to gently clean the affected skin and pat it dry. Apply a small amount (about the size of a pea) of the medication with your fingertips to the affected area in a thin layer.

Be careful to avoid using the gel around your eyes and lip area. Do not apply Biacna Topical Gel to cut, scraped, sunburned, or eczema-affected skin. Furthermore, it should not be applied to the inner lip area or inside the nose/mouth.

If the medication accidentally gets into your eyes, flush them with large amounts of water and contact your doctor if there is any eye irritation. Wash your hands after applying the medication to avoid accidentally getting it in your eyes.

During the first few weeks of using Biacna Topical Gel, your acne may appear worse before it gets better. It may take several weeks to see results from using the gel.

To ensure the best results, use the medication regularly at the same time each day. Do not use a larger amount or use it more frequently than recommended as this increases the risk of redness, peeling, and pain without improving the effectiveness of the medication.

Side Effects

Common Side Effects of Biacna Topical Gel (Clindamycin/Tretinoin):

  • Headache
  • Sinus infections
  • Skin irritation due to dryness, redness, peeling, burning, or stinging
  • Sunburn
  • Temporary change in skin color

Serious Side Effects of Biacna Topical Gel (Clindamycin/Tretinoin):

  • Red, swollen, blistered, or crusted skin
  • Severe abdominal cramps, pain, or bloating
  • Severe watery diarrhea that may be bloody
  • Signs of an allergic reaction (rash, hives, swelling of the lips or face, difficulty breathing)

Forms and Strength

Biacna Topical Gel (Clindamycin/Tretinoin) is available in the following forms and strength:

Biacna Topical Gel: Topical Gel

  • 1.2/0.025%


  • Avoid exposure to sunlight, as the medication can increase sensitivity to sunlight and sunburn may occur more easily. It is recommended to use protective clothing and sunscreen when going outside.
  • Do not use other topical acne or skin products containing a peeling agent or abrasive cleansers, medicated or abrasive soaps, or products containing sulfur, resorcinol, or salicylic acid unless instructed by your healthcare provider.
  • Avoid using the medication near the eyes, mouth, and mucous membranes.
  • Do not use the gel during pregnancy or while breastfeeding unless specifically instructed by a healthcare provider.
  • Biacna topical gel may cause skin irritation, redness, or peeling. If irritation or allergic reaction occurs, the use of the medication should be discontinued, and medical attention should be sought.
  • Notify your healthcare provider if you have any medical conditions or are taking any medications before using Biacna topical gel.
  • Do not use more than the recommended amount of medication on the skin, as this may increase the risk of side effects.
  • Do not apply the medication to broken, sunburned, or irritated skin.
  • If the Biacna topical gel is accidentally ingested, seek medical attention immediately.
  • Use caution when applying the medication near the nostrils or mouth, as it may be ingested or inhaled.
  • Keep the medication out of reach of children and pets.

Frequently Asked Questions (FAQ)

How does Biacna Topical Gel work?

Biacna Topical Gel contains two active ingredients, clindamycin and tretinoin. Clindamycin is an antibiotic that helps to kill the bacteria that causes acne. Tretinoin is a form of vitamin A that helps to reduce the size of oil glands in the skin and to prevent the formation of new acne bumps.

How do I use Biacna Topical Gel?

The gel is applied once daily, in the evening. Wash your face with a mild soap and water, pat it dry and wait for 20-30 minutes before applying the gel. Apply a small amount of the gel to the affected areas of your face and gently rub it in.

Can Biacna Topical Gel be used during pregnancy or while breastfeeding?

There is no clear answer. Pregnant and breastfeeding women should talk to their doctor before using Biacna Topical Gel.


It's important to purchase Biacna Topical Gel from verified Canadian pharmacy.

Additional information

Generic name:

Clindamycin Phosphate/Tretinoin


Topical Gel



Quantities Available:



Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Ziana (Clindamycin Phosphate/Tretinoin). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Ziana (Clindamycin Phosphate/Tretinoin).