Uniphyl SR (Theophylline)

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Uniphyl SR Brand

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Theophylline (Generic alternate to Uniphyl SR) Generic
Dosage Quantity & Price
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Uniphyl is a bronchodilator medication prescribed for the treatment of the symptoms and reversible airflow obstruction associated with chronic asthma and other chronic lung diseases, such as emphysema and chronic bronchitis. It can be indicated regularly to prevent wheezing and shortness of breath.

Uniphyl is a sustained-release tablet containing theophylline, which is a bronchodilator. It works by relaxing the muscles in the airways of the lungs, making it easier to breathe.

Theophylline also helps to reduce the sensitivity of the lungs to irritants, which can trigger asthma symptoms. Uniphyl SR (Sustained Release) is a long-acting medication that is designed to deliver theophylline over a period of 24 hours, providing sustained relief of asthma and COPD (Chronic Obstructive Pulmonary Disease) symptoms.

Use and Dosage

Theophylline comes in the form of an extended-release table to take by mouth as directed by your doctor, usually once a day in the morning or evening. Do not crush or chew the tablets. Doing so can release all the drug at once, increasing side effects risk. The tablet should be swallowed whole tablet with a full glass of water. Scored tablets may be split into two equal parts, if necessary, based on the healthcare provider's recommendation.

The recommended dosage of Theophylline ER (Extended Release) 24-hour scored tablet can vary depending on the patient's age, weight, medical history, and response to treatment. Follow the dosage instructions provided by the healthcare provider. However, the general dosing range for Theophylline ER 24-hour scored tablet is 400-600 mg per day, taken once or twice daily.

If you miss a dose of Uniphyl SR, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.

Side Effects

Common Side Effects of Uniphyl SR (Theophylline):

  • Diarrhea
  • Difficulty falling asleep or staying asleep
  • Headache
  • Irritability
  • Nausea
  • Restlessness
  • Stomach pain
  • Upset stomach
  • Vomiting

Serious Side Effects of Uniphyl SR (Theophylline):

  • Central nervous system excitement
  • Difficulty urinating (elderly males with prostates)
  • Exfoliative dermatitis
  • Fast heart rate, flutter
  • High calcium levels (hypercalcemia) (with concomitant hyperthyroid disease)
  • Increased or rapid heart rate
  • Increased urination (transient)
  • Insomnia
  • Irregular heartbeat
  • Irritability
  • Rash
  • Restlessness
  • Seizures
  • Skeletal muscle tremors

Forms and Strength

Uniphyl SR (Theophylline) is available in the following forms and strength:

Theophylline: ER 24hour Scored Tablet

  • 400mg
  • 600mg


  • Uniphyl SR should not be used in patients who are allergic to theophylline or any of the other ingredients in the medication.
  • Theophylline should be used with caution in patients with a history of seizures, as the medication can lower the seizure threshold.
  • Theophylline should be used with caution in patients with liver or kidney disease, as the medication is metabolized in the liver and excreted by the kidneys.
  • Uniphyl SR may interact with certain other medications, such as cimetidine, erythromycin, fluvoxamine, and others. Tell your doctor or pharmacist about all medications you are currently taking before beginning treatment with Uniphyl SR.
  • Uniphyl SR may cause side effects such as headache, nausea, vomiting, tremors, and others. If you experience any unusual or severe side effects while taking Uniphyl SR, contact your doctor right away.
  • Theophylline should be used with caution in patients with heart disease, as the medication can increase heart rate and may cause arrhythmias.
  • Uniphyl SR should be used with caution in pregnant women, as there is limited information about its safety during pregnancy. Discuss the risks and benefits of using the medication during pregnancy with your doctor.
  • Theophylline may interact with certain foods and beverages, such as caffeine, alcohol, and charcoal-grilled foods. Avoid or limit these substances while taking Uniphyl.
  • The tablet should be swallowed whole and not crushed, chewed, or dissolved, as it can cause too much of the medication to be released at once and lead to serious side effects.
  • Uniphyl SR should be stored in a cool, dry place away from heat and moisture.
  • Theophylline should not be used to treat sudden breathing problems or asthma attacks, as it is not a rescue medication. A quick-relief medication such as albuterol should be used instead.

Frequently Asked Questions (FAQ)

What should I do if I miss a dose of Uniphyl?

If you miss a dose of Uniphyl, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.

Is Uniphyl SR available without a prescription?

No, Uniphyl SR is a prescription medicine that should only be taken as directed by your doctor.

Can Theophylline be taken by children?

It should not be used for children under 12 years of age without the advice of a doctor.

How long does Theophylline take to start working?

Theophylline may take several days to achieve its full effect. Take it regularly as prescribed by your doctor to get the maximum benefit.


It's important to purchase Uniphyl SR from verified Canadian pharmacy.

Additional information

Generic name:



ER 24hour Scored Tablet, Extended Release 24hour Tablet


400mg, 600mg

Quantities Available: