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Synjardy contains two active ingredients: empagliflozin and metformin hydrochloride. It is a prescription medication used to help improve blood sugar control in adults with type 2 diabetes mellitus.
Synjardy is used together with a healthy diet and regular physical activity to help manage blood glucose levels. It may be prescribed when treatment with diet and exercise alone, or other diabetes medications, does not provide enough blood sugar control.
Synjardy is not used to treat type 1 diabetes and should not be used to treat diabetic ketoacidosis (DKA), a serious condition caused by a buildup of ketones in the blood.
Synjardy is used to improve glycemic control, which means helping maintain healthier blood sugar levels, in adults with type 2 diabetes.
Type 2 diabetes occurs when the body does not use insulin properly or does not produce enough insulin to control blood glucose levels. Over time, uncontrolled high blood sugar can increase the risk of complications affecting the heart, kidneys, nerves, eyes, and blood vessels.
By combining two medications that work in different ways, Synjardy helps lower blood sugar more effectively as part of a complete diabetes management plan.
Synjardy combines two diabetes medications: empagliflozin and metformin.
Empagliflozin
Empagliflozin belongs to a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors.
It works by blocking the SGLT2 protein in the kidneys. Normally, this protein helps return glucose from the urine back into the bloodstream. By blocking SGLT2, empagliflozin allows more glucose to leave the body through urine, which helps lower blood sugar levels.
Metformin
Metformin belongs to a class of medications called biguanides.
It helps lower blood sugar by reducing the amount of glucose produced by the liver and improving the body’s sensitivity to insulin. This allows the body to use insulin more effectively and helps glucose move from the bloodstream into cells where it can be used for energy.
When used as prescribed, Synjardy may help:
Synjardy works best when taken along with recommended diet, exercise, and regular monitoring as advised by your healthcare provider.
Synjardy helps manage type 2 diabetes but does not cure the condition. Continue following your diabetes care plan, including healthy eating, physical activity, and regular medical checkups.
Your healthcare provider may monitor your blood sugar levels, kidney function, and overall response to treatment to ensure Synjardy remains safe and effective for you.
Synjardy is available as an oral tablet containing two medications: empagliflozin and metformin. Take Synjardy exactly as prescribed by your healthcare provider.
It is usually taken twice daily with meals to help reduce stomach-related side effects from metformin. Take each dose at approximately the same time every day to help maintain consistent blood sugar control and make it easier to remember.
Swallow Synjardy tablets whole with water. Do not split, crush, dissolve, or chew the tablets, as this may affect how the medication is released and absorbed.
Drink enough fluids while taking Synjardy to help prevent dehydration, especially if you experience increased urination, hot weather, illness, or fluid loss.
Tell your healthcare provider and pharmacist about all medications, vitamins, supplements, and herbal products you take. Some products may affect how Synjardy works or increase the risk of side effects.
The dose of Synjardy is individualized based on factors such as:
For patients who are already taking empagliflozin and metformin separately, the healthcare provider may switch to Synjardy using a tablet strength that provides a similar total daily dose of each medication.
For patients starting treatment or changing therapy, the dose may be adjusted gradually based on blood sugar response and tolerability.
The maximum recommended daily dose of Synjardy is:
Your healthcare provider will determine the appropriate dose and should not exceed these maximum daily limits.
Do not increase, decrease, or stop taking Synjardy without first speaking with your healthcare provider.
Synjardy (Empagliflozin/metformin hcl) is available in the following forms and strength:
Talk to your healthcare provider about whether alcohol is safe for you while taking Synjardy and how much you can consume.
Alcohol may increase the risk of low blood sugar (hypoglycemia), especially when combined with other diabetes medications. It may also increase the risk of lactic acidosis, a rare but serious condition associated with metformin.
Avoid excessive alcohol consumption and follow your healthcare provider’s recommendations.
Synjardy should not be used in people with severe kidney impairment because both empagliflozin and metformin depend on kidney function for safe use.
Your healthcare provider will check your kidney function before starting Synjardy and may continue monitoring it during treatment.
Tell your healthcare provider if you have kidney disease, dehydration, or conditions that may affect kidney function.
Synjardy should not be used in people with a history of diabetic ketoacidosis (DKA) unless specifically directed by a healthcare provider.
Seek medical attention if you develop symptoms that may suggest ketoacidosis, such as nausea, vomiting, stomach pain, unusual tiredness, difficulty breathing, or confusion.
Synjardy may cause low blood sugar, especially when taken with other medications that lower blood glucose, such as insulin or sulfonylureas.
Symptoms of low blood sugar may include:
Your healthcare provider may adjust the doses of your other diabetes medications to reduce the risk of hypoglycemia.
Metformin, one of the ingredients in Synjardy, can rarely cause a serious condition called lactic acidosis, which is a buildup of lactic acid in the blood.
The risk may be higher in people with kidney problems, severe dehydration, excessive alcohol use, liver problems, heart failure, or certain serious infections.
Seek immediate medical attention if you experience symptoms such as:
Empagliflozin increases the amount of glucose removed through urine, which may increase the risk of genital yeast infections.
Symptoms may include:
People with a history of frequent genital infections may have a higher risk. Contact your healthcare provider if symptoms occur.
Older adults may have a higher risk of side effects, particularly those related to kidney function, dehydration, dizziness, and low blood pressure.
Your healthcare provider may monitor kidney function more closely and adjust treatment if needed.
Very high or very low blood sugar levels may cause blurred vision, dizziness, drowsiness, or difficulty concentrating.
Do not drive, operate machinery, or perform activities requiring alertness or clear vision until you know how Synjardy affects you and your blood sugar levels are controlled.
There is limited information about the safety of Synjardy during pregnancy.
Talk to your healthcare provider if you are pregnant, planning to become pregnant, or think you may be pregnant. Your healthcare provider will discuss the potential benefits and risks and determine whether another treatment may be more appropriate.
Metformin may improve ovulation in some people with insulin resistance or certain menstrual irregularities. This may increase the chance of becoming pregnant.
If pregnancy is not desired, discuss reliable birth control options with your healthcare provider or pharmacist while taking Synjardy.
No. Synjardy is not appropriate for everyone. Before starting Synjardy, your healthcare provider will review your medical history, kidney function, current medications, and other health conditions to determine whether it is a safe and suitable treatment option for you. Synjardy may not be appropriate for people with certain conditions, including severe kidney problems, a history of diabetic ketoacidosis (DKA), or certain situations that increase the risk of lactic acidosis. Always tell your healthcare provider about all prescription medications, over-the-counter products, vitamins, and supplements you take before starting Synjardy.
Yes. Synjardy may cause low blood sugar (hypoglycemia), especially when it is taken with other medications that lower blood sugar, such as insulin or sulfonylureas. Symptoms of low blood sugar may include shaking, sweating, hunger, dizziness, confusion, weakness, fast heartbeat, or irritability. Your healthcare provider may adjust the dose of your other diabetes medications to reduce the risk of hypoglycemia. Learn how to recognize and manage low blood sugar and follow your healthcare provider’s instructions.
Synjardy begins working after the first dose by helping lower blood sugar through two different mechanisms. Empagliflozin starts working by helping the kidneys remove glucose through urine, while metformin begins reducing glucose production in the liver and improving the body’s response to insulin. However, noticeable improvements in blood sugar levels may take several weeks of regular use. Your healthcare provider will monitor your blood sugar and adjust your treatment if needed. Continue taking Synjardy as prescribed, even if you do not notice immediate changes.
Take Synjardy exactly as prescribed by your healthcare provider. It is usually taken twice daily with meals to help reduce stomach-related side effects from metformin. Take it at the same times each day to maintain consistent blood sugar control. Swallow the tablet whole with water. Do not crush, chew, split, or dissolve the tablet. Follow your healthcare provider’s instructions regarding diet, exercise, blood sugar monitoring, and any other diabetes medications you use.
| Generic name: | Empagliflozin/Metformin, Empagliflozin/Metformin hcl, Empagliflozin/metformin hcl |
|---|---|
| Formulation: | ER Tablet, Film Coated Tablet, Tablet |
| Strength(s): | 5/500mg, 5/1000mg, 12.5/500mg, 12.5/1000mg |
| Quantities Available: | 60, 100, 120, 180 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Synjardy (empagliflozin/metformin HCL) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Synjardy is available in various strengths, including: 5/500 mg,
5/1000 mg, 12.5/500 mg, and 12.5/1000 mg. The dosage prescribed will depend on your specific treatment plan.
For example, if you are prescribed Synjardy 12.5/1000 mg twice daily, you would order 180 tablets for a 90-day supply (90 days x 2 tablets per day).
No, we do not sell empagliflozin/metformin HCL directly. However, you can still enjoy competitive prices on Synjardy, which contains empagliflozin/metformin HCL as its active ingredient. To purchase Synjardy from our website, you will need a valid prescription from your healthcare provider. We require this to dispense the medication safely and legally. You can conveniently submit your prescription by mailing it, faxing it, or uploading it through your online account on our website.
Yes, we ship Synjardy (empagliflozin/metformin hcl) to both the United States and Puerto Rico.
Watch how Online Pharmacies Canada is helping customers save money on their medications.
Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Synjardy (Empagliflozin/metformin hcl). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Synjardy (Empagliflozin/metformin hcl).
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