Silkis Ointment (Calcitriol)

Indications

Silkis Ointment is a medication used for the topical treatment of mild to moderately severe plaque psoriasis (psoriasis vulgaris) with up to 35% or up to one-third of body surface area involvement. It contains the active ingredient calcitriol, which is a vitamin D analogue or a nonsteroidal antipsoriatic agent.

Calcitriol works by decreasing the excessive growth and inflammatory response of skin cells that cause psoriasis symptoms. By doing so, Silkis Ointment helps to improve the appearance of psoriasis lesions and alleviate associated symptoms such as redness, itching, and scaling.

Use and Dosage

Silkis Ointment should be applied to the affected area(s) of the skin twice daily. The area(s) should be clean and dry before applying the ointment.

To use Silkis Ointment, clean and dry the affected areas of the skin before applying a thin layer of the ointment twice daily, in the morning and evening. The ointment should be gently rubbed onto the skin until it is evenly distributed. Do not use more than the maximum daily recommended amount of 30g of ointment per day and do use the ointment for more than 6 weeks as safety beyond this period has not been established. Avoid getting the ointment in contact with eyes, mucous membranes or significant skin injury or damage. Talk to a healthcare professional for guidance on how to use Silkis Ointment safely and effectively.

Use Silkis Ointment exactly as prescribed by your doctor. If you miss a dose, apply it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Side Effects

Common Side Effects of Silkis Ointment (Calcitriol):

• Abnormal laboratory test results, including urine tests
• Flu-like symptoms
• High amounts of calcium in urine
• Itch
• Psoriasis symptoms
• Skin discomfort

Serious Side Effects of Silkis Ointment (Calcitriol):

• Difficulty breathing or swallowing
• Excessive thirst
• Excessive urination
• Nausea
• Rashes or blisters over the body
• Skin infection
• Swelling of the hands, feet, ankles, face, lips, mouth, or throat
• Vomiting

Forms and Strength

Silkis Ointment (Calcitriol) is available in the following forms and strength:

Silkis Ointment: Ointment

• 3mcg/g

Cautions

• Patients receiving medications known to increase serum calcium levels should use Silkis Ointment with caution.
• People who are taking calcium supplements, high doses of vitamin D, or other medicines that can increase the amount of calcium in the blood should use Silkis Ointment with caution.
• Silkis Ointment should be used with caution in patients with severe kidney disease. Note that this is not a complete list of all cautions. Please consult a healthcare professional for more information on using Silkis Ointment.
• Silkis Ointment should not be used in patients who have a known hypersensitivity to calcitriol or any of the other components of the ointment.
• Avoid using Silkis Ointment during pregnancy or while breastfeeding without consulting a healthcare professional, as it has not been studied in pregnant or breast-feeding women.
• Silkis Ointment should be used with caution in patients with known or suspected calcium metabolism disorders, such as hyperparathyroidism or tumor-induced osteomalacia.
• Avoid applying the ointment to areas with significant skin injury or damage, such as a cut or burn.
• Silkis Ointment is for external use only and should not be ingested or applied to the eyes or mucous membranes. Again, this is not an exhaustive list of all the possible cautions associated with Silkis Ointment use. Talk to a healthcare professional for more information about potential risks and precautions while using it.

Frequently Asked Questions (FAQ)

Can Silkis Ointment be used during pregnancy or while breastfeeding?

Silkis Ointment should be used with caution during pregnancy or while breastfeeding, and only under the guidance of a healthcare professional.

Can Silkis Ointment be used for children?

The safety and efficacy of Silkis Ointment in children have not been established. Please consult a healthcare professional for more information on whether it is appropriate for your child.

Is a prescription required to purchase Silkis Ointment?

Yes, a prescription is required to purchase Silkis Ointment. Please consult a healthcare professional for more information on obtaining a prescription.

Resources

• https://www.netdoctor.co.uk/medicines/skin-hair/a8632/silkis-ointment-calcitriol/
• https://www.galderma.com/sites/default/files/inline-files/Silkis%20%28calcitriol%29%20PM_E_Sep%2016%2C%202019.pdf
• https://patient.info/medicine/calcitriol-ointment-for-psoriasis-silkis
• https://www.medbroadcast.com/drug/getdrug/silkis
• https://www.oxfordonlinepharmacy.co.uk/psoriasis/silkis-ointment-3mcg-100g-calcitriol