Sandomigraine (Pizotifen) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet


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Prescription Prescription Required FormationFormulation: Tablet


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Sandomigraine (generically known Pizotifen) is aprescription medication primarily used as a preventive medication for migraine headaches. It works by blocking the action of certain brain chemicals responsible for causing migraines.

Sandomigraine is not used to treat headaches once they have started, but it can be helpful in reducing the frequency and severity of migraines when taken regularly.

Use and Dosage

Pizotifen comes in the form of Tablet to take by mouth usually to three tablets each day. Take the tablets with water or other liquid. They can be taken with or without food. They should be swallowed whole with water or after food to reduce the likelihood of stomach upset. Chewing the tablet may alter the way the medication is absorbed by your body and may lead to reduced effectiveness.

The usual dose for adults is 0.5 to 1.5 mg daily, divided into one or two doses. The dosage may be adjusted based on your age, weight, and response to treatment. Do not exceed the recommended dose unless directed by your doctor. Take the tablets with or after food to reduce the likelihood of stomach upset. It may take several weeks for the medication to start working, continue taking it even if you do not notice immediate improvement.

Take Sandomigraine exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is less than 4 hours until your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Side Effects

Common Side Effects of Sandomigraine (Pizotifen):

  • Dizziness
  • Drowsiness
  • Dry mouth
  • Fatigue
  • Increased appetite
  • Nausea
  • Weight gain

Serious Side Effects of Sandomigraine (Pizotifen):

  • Aggressive behavior or agitation in children
  • Changes in sleep
  • Changes in weight
  • Dark urine
  • Decreased interest in activities
  • Diarrhea
  • Difficulty breathing
  • Hallucinations
  • Hives
  • Loss of appetite
  • Low blood pressure
  • Muscle and joint pain
  • Nausea
  • Pale stools
  • Poor concentration
  • Seizures
  • Sensation of tingling or prickling
  • Swelling of the throat or mouth
  • Thoughts of suicide
  • Vision changes
  • Vomiting
  • Weight loss
  • Yellowing of the skin or whites of the eyes

Forms and Strength

Sandomigraine (Pizotifen) is available in the following forms and strength:

Pizotifen: Tablet

  • 0.5 mg


  • Use with caution in patients with epilepsy.
  • Withdrawal symptoms like depression, tremor, nausea, anxiety, malaise, dizziness, sleep disturbance may occur if the medication is suddenly discontinued.
  • Sandomigraine may cause drowsiness or dizziness and may impair the ability to operate machinery or drive a car.
  • Follow the dosage instructions carefully and not exceed the recommended dose.
  • Sandomigraine may interact with other medications including antidepressants, sedatives, and certain blood pressure medications. inform the doctor about all medications being taken.
  • It should not be used during pregnancy or breastfeeding without consulting a doctor.

Frequently Asked Questions (FAQ)

Can Sandomigran be taken during pregnancy or breastfeeding?

It is not recommended to take Sandomigran during pregnancy or breastfeeding, as its safety has not been established.

Is Sandomigran a triptan?

No, Sandomigran is not a triptan. It belongs to a class of drugs called serotonin antagonists.

Can Sandomigran be used to treat acute migraines?

No, Sandomigran is not effective in treating acute migraines. It is only used for prevention.

Can Sandomigran be used in children?

Yes, Sandomigran can be used in children over 2 years of age for migraine prevention. However, dosages may need to be adjusted based on weight.


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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Sandomigraine (Pizotifen). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Sandomigraine (Pizotifen).