Indications
Rexulti (brexpiprazole) is a prescription medication used to treat schizophrenia, bipolar disorder, and major depressive disorder (MDD). It is an atypical antipsychotic drug that works by changing the activity of certain natural substances in the brain. Rexulti is known for being effective in treating major depressive disorder and reducing symptoms associated with it. It can also help improve thinking, mood, and behavior, as well as reduce the risk of suicidal thoughts or attempts among those suffering from depression or other mental illnesses.
In the case of schizophrenia, Rexulti can be used as a monotherapy or in combination with other medications, and for MDD it is prescribed as an add-on treatment to an antidepressant to help build on any progress that has already been made. Rexulti is not approved for the treatment of people with dementia-related psychosis.
Uses and Dosage
Rexulti comes in the form of Rexulti to take by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition, response to treatment, and other drugs you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.
The recommended starting dose of Rexulti is 1 mg once daily, and it may be increased to 2 mg, 3 mg, or 4 mg once daily depending on the condition being treated and the individual patient's response to the medication.
Side effect
Common Side Effects of Rexulti (Brexpiprazole):
- Dizziness
- Drowsiness
- Headache
- Lightheadedness
- Fatigue
- Increased appetite
- Weight gain
- Restlessness
- Agitation
- Stuffy nose
Serious Side Effects of Rexulti (Brexpiprazole):
- Fainting
- Hypotension
- Increase in blood sugar level
- Sleep apnea
- Tardive dyskinesia characterized by uncontrolled movements
- Trouble swallowing
- Unusual strong urges
Form and strength
Rexulti (Brexpiprazole) is available in the following forms and strength:
Rexulti: Tablet
- 0.25mg
- 0.5mg
- 1mg
- 2mg
- 3mg
- 4mg
Caution
- The safety of Rexulti during pregnancy and breastfeeding has not been established, and it should only be used if the potential benefits outweigh the potential risks to the fetus or infant. Consult with a healthcare provider before taking brexpiprazole during pregnancy or while breastfeeding.
- brexpiprazole can interact with other medications such as fluoxetine and paroxetine, which may increase the risk of adverse reactions.
- Rexulti can cause side effects, although the specific side effects vary among individuals.
- The safety and efficacy of Rexulti have not been established in pediatric patients.
- Elderly patients with dementia-related psychosis treated with antipsychotic drugs such as brexpiprazole are at an increased risk of death.
- Rexulti has a boxed warning, indicating that it carries a significant risk of serious or even life-threatening adverse effects.
Frequently Asked Questions (FAQ)
What are the important safety considerations for taking Rexulti?
Rexulti comes with important safety information and a boxed warning, which includes an increased risk of death in elderly patients with dementia-related psychosis.
Can I enroll in a patient support program for brexpiprazole?
Yes, there is a patient support program called the Patient Enrollment Line (PEL) that can help answer questions related to access, treatment, and insurance.
How is Rexulti taken?
Rexulti is usually taken orally once per day with or without food, as directed by a healthcare provider.
How long does it take for brexpiprazole to start working?
Brexpiprazole may start to have an effect on symptoms within the first few weeks of treatment, but it can take several weeks to see the full effects of the medication.
How should Rexulti be stored?
Rexulti should be stored at room temperature away from moisture and heat. It should be kept in its original packaging and out of the reach of children.
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