Indications
Relafen (Nabumetone) is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis and rheumatoid arthritis. It helps reduce pain, swelling, and joint stiffness associated with these conditions. It works by blocking the production of hormones that cause pain and inflammation in the body.
Nabumetone can be taken orally or applied directly to the affected area through a topical form. It exhibits anti-inflammatory, analgesic, and antipyretic properties, and is known to reduce pain, swelling, and joint stiffness commonly associated with arthritis. Compared to other similar medications in its class, Nabumetone is associated with a lower risk of stomach-related side effects.
Uses and Dosage
To take Nabumetone, you should take it orally as a tablet, usually once or twice daily, with or without food. Do not lie down for at least 10 minutes after taking this drug. To prevent stomach upset, take it with food, milk, or an antacid.
If there is anything you do not understand about taking Nabumetone, ask your doctor or pharmacist to explain it to you. Take it at the same time every day and follow the directions on your prescription label carefully and do not take more or less of it or take it more often than prescribed.
- For osteoarthritis and rheumatoid arthritis, Nabumetone is usually prescribed at a starting dose of 1000mg to be taken once or twice daily with or without food. Some patients may benefit from an increased dose of 1500mg to 2000mg per day.
- To reduce the risk of renal effects, the lowest effective dose should be used for chronic treatment. Patients weighing less than 50kg may not require dosages beyond 1000mg, so adjustments to the dose should be made based on the individual patient's response to initial therapy.
Side Effect
Common Side Effects of Relafen (Nabumetone):
- Constipation
- Diarrhea
- Difficulty falling asleep or staying asleep
- Dizziness
- Dry mouth
- Gas or bloating
- Headache
- Increased sweating
- Loss of appetite
- Nausea
- Nervousness
- Ringing in the ears
- Sores in the mouth
Serious Side Effects of Relafen (Nabumetone):
- Back pain
- Blisters
- Cloudy, discolored, or bloody urine
- Difficult or painful urination
- Difficulty breathing or swallowing
- Fast heartbeat
- Fever
- Flu-like symptoms
- Hives
- Hoarseness
- Itching
- Lack of energy
- Pain in the upper right part of the stomach
- Pale skin
- Rash
- Shortness of breath or difficulty breathing
- Swelling of the abdomen, feet, ankles, or lower legs
- Swelling of the eyes, face, lips, tongue, throat, arms, or hands
- Unexpected weight gain
- Yellowing of the skin or eyes
Form and Strength
Relafen (Nabumetone) is available in the following forms and strength:
Relafen: Tablet
- 500 mg
Nabumetone: Tablet
- 500 mg
- 750 mg
Caution
- Using NSAIDs like Relafen may increase the risk of heart attack, stroke, and other cardiovascular events, particularly when taken for prolonged periods or at high doses.
- Drinking alcohol while taking Relafen may increase the risk of stomach bleeding and other side effects. It is best to avoid alcohol while taking this medication.
- To reduce your risk of side effects while taking Relafen, you should take it exactly as prescribed, avoid drinking alcohol or taking other NSAIDs while taking it, and talk to your doctor before taking any new medications or supplements.
- Avoid taking other NSAIDs (such as ibuprofen or aspirin) while taking Relafen, as it can increase your risk of side effects. You should also talk to your doctor before taking any new medications, including over-the-counter drugs and herbal supplements.
- Do not stop taking Relafen suddenly without talking to your doctor first. Your doctor may need to gradually taper your dose to avoid withdrawal symptoms.
- Relafen can cause dizziness and drowsiness. Do not drive or operate heavy machinery until you know how Relafen affects you.
- Talk to your doctor before taking any other medications while on Relafen. This includes other over-the-counter medications, herbal supplements, and prescription drugs. Certain medications may interact with Relafen and cause adverse side effects.
- If you miss a dose of Relafen, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Frequently Asked Questions (FAQ)
Can I take Relafen with food?
Yes, you can take Relafen with food to help reduce the risk of stomach upset.
Can Relafen be addictive?
No, Relafen is not known to be addictive.
How long does it take for Relafen to start working?
Relafen may take several weeks to start working to reduce pain and inflammation.
Can Relafen be taken for a long period of time?
Relafen should be taken for the shortest duration possible to manage symptoms, due to an increased risk of side effects with prolonged use.
Resources
- https://www.drugs.com/relafen.html
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/019583s025lbl.pdf
- https://www.everydayhealth.com/drugs/nabumetone
- https://www.webmd.com/drugs/2/drug-7004/relafen-oral/details
- https://medlineplus.gov/druginfo/meds/a692022.html
- https://www.rxlist.com/relafen-drug.htm
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