Indications
Ranexa (active ingredient: ranolazine ER) is a prescription medication indicated for the following:
- Chronic Angina: Ranexa is used for the treatment of chronic angina in adults. It is typically prescribed as an adjunctive therapy for patients who have not achieved adequate symptom relief with other anti-anginal medications.
Ranexa belongs to a class of drugs known as anti-anginal agents, which work by improving blood flow to help the heart work more efficiently, thereby reducing the frequency and severity of angina episodes.
Uses and Dosage
Ranolazine is available in tablet form to be taken orally with or without food, as directed by a healthcare provider, usually twice daily. To reduce the risk of side effects, swallow the tablet whole and do not crush, split, or chew it.
Inform your doctor and pharmacist of all products you use, including prescription drugs, non-prescription drugs, and herbal products. Do not take more than the prescribed amount. Speak with your doctor or pharmacist for further information. If a dose of RANEXA tablet is missed, take the prescribed dose at the next scheduled time; do not double the next dose.
The starting dose of Ranexa is 500 mg twice daily, which may be increased to 1000 mg twice daily based on clinical symptoms. The maximum recommended dose of Ranexa is 1000 mg twice daily. Ranexa is generally safe and well-tolerated with minimal side effects.
Side Effect
Common Side Effects of Ranexa (Ranolazine Er):
- Constipation
- Dizziness
- Headache
- Nausea
Serious Side Effects of Ranexa (Ranolazine Er):
- Fast or pounding heartbeats
- Feeling tired
- Fluttering in your chest
- Lightheadedness
- Little or no urination
- Painful or difficult urination
- Shortness of breath
- Swelling in your feet or ankles
Form and Strength
Ranexa (Ranolazine Er) is available in the following forms and strength:
Ranexa: Prolonged Release Tablet
- 500 mg
Ranolazine Er: Extended-Release Tablet
- 500 mg
Caution
- Avoid consuming grapefruit or grapefruit juice while taking ranolazine, as it may increase the risk of side effects. Before consuming any grapefruit products, consult with a doctor or pharmacist to ensure it is safe to do so.
- Before taking ranolazine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. It may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
- During pregnancy, Ranexa should be used only when clearly needed. Discuss the risks and benefits with your doctor.
- One must be cautious in interpreting the results of ranolazine-mediated reductions in body weight, due to the limitations of the studies.
- Ranexa may cause side effects such as dizziness, spinning sensation, nausea, vomiting, stomach pain, constipation, headache, dry mouth, and others. Patients should be advised to consult their doctor if they experience any of these symptoms or other unusual effects.
- Ranexa should be used with caution in patients with pre-existing QT prolongation or who are taking medications that prolong the QT interval.
- Patients with certain pre-existing conditions such as liver disease, kidney disease, or electrolyte imbalances should be closely monitored when using Ranexa.
- Ranexa may cause changes in blood pressure and heart rate. Patients should be monitored for these changes and advised to report any symptoms to their healthcare provider.
Frequently Asked Questions (FAQ)
Is Ranexa effective for treating chronic stable angina?
Yes, Ranexa can be effective for treating chronic stable angina. However, follow the dosage and usage instructions provided by a healthcare professional.
How long does Ranexa take to work?
Ranexa may take a few weeks to work fully. It is important to continue taking the medication as prescribed and not to adjust the dosage without talking to a healthcare professional.
Can Ranexa be used during pregnancy or breastfeeding?
The safety of Ranexa during pregnancy and breastfeeding is not known. Women who are pregnant or breastfeeding should talk to a doctor before using Ranexa.
Is Ranexa a blood thinner?
No, Ranexa is not a blood thinner. It is used to treat angina by improving blood flow to the heart, but it does not thin the blood like other medications such as aspirin or warfarin.
Who should not take Ranexa?
Ranexa should not be taken by people with a certain type of irregular heart rhythm, severe liver disease, or an allergy to ranolazine. Inform a doctor about any medical conditions or allergies before taking Ranexa.
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