Optimmune (Cyclosporine) Shopper Approved

Prescription Prescription Required FormationFormulation: Eye Ointment


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Prescription Prescription Required FormationFormulation: Eye Ointment


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Optimmune is a prescription ophthalmic ointment specially formulated for dogs with immune system disorders, including dry eye, discharge, and discomfort. It is available as an ophthalmic ointment containing 0.2% cyclosporine. This ointment can be stored for up to 24 months without refrigeration. The ointment contains the immunosuppressant Cyclosporine which can effectively relieve swelling, and irritation associated with persistent eye conditions.

Cyclosporine is used to manage chronic keratoconjunctivitis sicca (KCS) and chronic superficial keratitis (CSK) in dogs. Optimmune works by decreasing inflammation and immune-mediated destruction of the tear-producing glands, thus helping to treat dry eye syndrome in dogs. Optimmune is also used to treat common eye infections in dogs.

Uses and Dosage

Cyclosporine ophthalmic can be administered as an ointment that is instilled in the eye two times a day. Use the instilled ointment approximately 12 hours apart and adhere to the instructions on your prescription label carefully.

For cyclosporine eye drops, it is recommended to use them at the same times each day as directed. Follow your prescription label strictly and consult your doctor or pharmacist if you have any questions or do not comprehend any part of the instructions. Avoid using more or less of the eye drops or use them more often than prescribed by your physician.

To use Cyclosporine Eye Ointment (such as Optimmune), first wash your hands thoroughly. Then, tilt your dog's head back slightly and pull down on their lower eyelid to create a small pocket. Squeeze a small amount of ointment (as prescribed by your veterinarian) into the pocket and release the lower eyelid. Allow your dog to blink a few times to spread the ointment evenly over the eye's surface. Be careful not to touch the tip of the tube to your dog's eye or any other surface to prevent contamination.

Side Effects

Common Side Effects of Optimmune (Cyclosporine):

  • Blurred vision or other vision changes
  • Burning, itching, stinging, redness, or pain of the eyes
  • Eye discharge
  • Eyelid swelling
  • Feeling that something is in the eye
  • Headache

Serious Side Effects of Optimmune (Cyclosporine):

  • Face, throat, eyes, and tongue swelling
  • Hives
  • Itching
  • Shortness of breath

Form and Strength

Optimmune (Cyclosporine) is available in the following forms and strength:

Cyclosporine: Eye Ointment

  • 0.2%


  • Optimmune should not be used in dogs with a known hypersensitivity to cyclosporine.
  • Optimmune should be used with caution in dogs with a history of hereditary or congenital immunodeficiency.
  • Optimmune should not be used in dogs with a viral or fungal eye infection.
  • Optimmune should be used with caution in dogs with a corneal ulcer, as it may delay the healing process.
  • Optimmune may cause a temporary burning or stinging sensation in the eye.
  • The safety of Optimmune has not been established in breeding or pregnant dogs, so caution should be taken when using it in these animals.
  • Optimmune should be used with caution in dogs with a history of malignant neoplasia or renal dysfunction, as cyclosporine may exacerbate these conditions.
  • Prolonged use of Optimmune may increase the risk of secondary infections or the development of resistance to the medication.
  • Optimmune may cause blurred vision or other changes in vision in some dogs, particularly with higher doses.
  • Optimmune should not be used in conjunction with other immunosuppressive medications without veterinary guidance.
  • Optimmune may not be effective in all cases of dry eye or other eye conditions, so follow up with your veterinarian regularly to assess its effectiveness and adjust treatment as needed.
  • Optimmune may cause some side effects, such as redness, irritation, or discharge from the eye. If you notice these or any other side effects, contact your veterinarian.
  • Optimmune may interact with other medications, so inform your veterinarian of any other medications your dog is taking.

Frequently Asked Questions (FAQ)

What is Optimmune?

Optimmune is a prescription ophthalmic (eye) ointment containing the active ingredient cyclosporine. It is used to treat keratoconjunctivitis sicca (dry eye) in dogs.

Is Optimmune safe for dogs?

Optimmune is generally safe for use in dogs when used as directed by a veterinarian. However, like all medications, it may cause side effects in some dogs. Contact your veterinarian if you notice any unusual symptoms or side effects in your dog.

Can Optimmune be used for cats?

Optimmune has not been approved for use in cats. The safety and efficacy of the medication in cats has not been established.

How long should I use Optimmune?

Follow the instructions provided by your veterinarian carefully. In general, Optimmune is used twice daily, every day for the rest of your dog's life.


Additional information

Generic name:



Eye Ointment



Quantities Available:

5g, 10g


Additional Information Book

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Optimmune (Cyclosporine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Optimmune (Cyclosporine).