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Frontline Plus for Cats (Fipronil/methoprene) Shopper Approved

Prescription Prescription Not Required FormationFormulation: Pippettes

Frontline Plus for Cats

(Brand Option)

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Prescription Prescription Not Required FormationFormulation: Pippettes

Fipronil/methoprene

(Generic Alternative)

Select the prescribed dosage

Select the quantity to see the price.

  *  
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* This price includes a dispensing fee, medical review fee, and packing fee.

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Frontline Plus for Cats contains two active ingredients, fipronil and (S)-methoprene. It is a topical parasite treatment used to help protect cats against fleas and certain ticks.

It is intended for cats and kittens 8 weeks of age and older and is applied directly to the skin, usually between the shoulder blades where the cat cannot easily lick the application site.

Flea Infestations

Frontline Plus for Cats helps kill adult fleas that are already living on your cat.

Fleas feed on blood and can cause itching, scratching, skin irritation, and discomfort. Heavy infestations may be especially troublesome for kittens, older cats, or cats with other health problems.

Flea Eggs and Larvae

Frontline Plus does more than kill adult fleas.

The ingredient (S)-methoprene helps prevent flea eggs and larvae from developing normally. This is important because most of the flea population may actually exist in immature stages in the surrounding environment rather than as adult fleas on the cat.

Breaking the Flea Life Cycle

A flea infestation can continue when adult fleas lay eggs, which then develop into larvae, pupae, and eventually new adult fleas.

By killing adult fleas and interfering with immature flea stages, Frontline Plus helps break the flea life cycle and reduce repeated infestations.

Flea Allergy Dermatitis

Some cats are highly sensitive to flea bites and may develop flea allergy dermatitis.

Even a small number of flea bites can cause intense itching, excessive grooming, hair loss, scabs, or irritated skin in sensitive cats.

Keeping fleas under control may help reduce exposure to flea bites and the skin problems associated with them.

Tick Infestations

Frontline Plus for Cats also helps control certain species of ticks that may attach to a cat’s skin.

Ticks feed on blood and can remain attached for several days. Some species may carry infectious organisms, so checking your cat regularly and using appropriate tick protection can be important, especially for cats that spend time outdoors.

How Fipronil Works

Fipronil is the ingredient responsible for killing adult fleas and ticks.

It interferes with important chemical signals in the parasite’s nervous system. This causes uncontrolled nerve activity, eventually leading to the death of susceptible fleas and ticks.

How (S)-Methoprene Works

(S)-methoprene is known as an insect growth regulator.

Instead of mainly targeting adult fleas, it interferes with the normal development of flea eggs and larvae.

This helps prevent immature fleas from developing into reproducing adults.

Why Two Active Ingredients Are Used

The two ingredients work at different stages of the flea life cycle.

Fipronil targets adult fleas and ticks, while (S)-methoprene targets flea eggs and larvae.

Using both ingredients helps provide more complete flea control than targeting adult fleas alone.

How Frontline Plus Spreads Over the Cat

Frontline Plus is applied to the skin rather than rubbed throughout the coat.

After application, the active ingredients spread across the skin and coat through the natural oils on the skin. This allows the treatment to reach parasites that come into contact with the cat.

Why It Is Applied to the Skin

The medication should be placed directly on the skin, not just on the fur.

Parting the hair before application helps make sure the liquid reaches the skin, where it can spread properly.

Applying it only to the hair may reduce how well the product works.

Ongoing Flea Protection

Frontline Plus is generally used on a regular treatment schedule to maintain protection.

Consistent use is important because new fleas can continue to emerge from carpets, bedding, furniture, and outdoor environments even after the adult fleas on the cat have been killed.

Fleas Can Also Live in the Home

Only part of a flea infestation is found directly on your cat.

Flea eggs, larvae, and pupae can be present in pet bedding, carpets, furniture, floor cracks, and other areas of the home.

For a significant infestation, treating the cat may need to be combined with regular vacuuming, washing pet bedding, and appropriate environmental flea-control measures.

Protection for Indoor Cats

Even cats that live entirely indoors can be exposed to fleas.

Fleas may be brought into the home by other pets, people, rodents, or visiting animals. Indoor cats may therefore still benefit from flea prevention depending on their household and exposure risk.

Protection for Outdoor Cats

Cats that spend time outdoors may have greater exposure to fleas and ticks, particularly in grassy, wooded, or brush-covered areas.

Regular parasite checks and consistent preventive treatment may be especially important for these cats.

Use the Cat Formulation Only

Always use Frontline Plus specifically labeled for cats.

Do not substitute another flea or tick product simply because it has a similar name or packaging. Products made for other species may contain different concentrations or ingredients and may not be safe for cats.

Use Only in Cats of the Appropriate Age

Frontline Plus for Cats is intended for cats and kittens 8 weeks of age or older.

For younger kittens, ask a veterinarian about appropriate flea-control options rather than using the product without professional guidance.

Regular Checks Are Still Important

Even when using flea and tick prevention, regularly check your cat’s skin and coat.

Look for signs such as fleas, flea dirt, ticks, excessive scratching, hair loss, scabs, or skin irritation.

If you continue to find parasites despite correct treatment, speak with your veterinarian.

What Frontline Plus Does Not Do

Frontline Plus helps control fleas and certain ticks, but it does not treat every type of parasite.

It does not replace treatments for intestinal worms, ear mites, heartworm, or other parasites unless the specific product label states otherwise.

Getting the Best Results

For the best protection, apply Frontline Plus directly to the skin, use it on the recommended schedule, avoid skipping treatments, and manage fleas in the home environment when necessary.

Consistent use helps kill adult fleas and ticks while also preventing flea eggs and larvae from developing into new adult fleas.

Frontline Plus for Cats is a topical parasite treatment that contains fipronil and (S)-methoprene. It is designed to protect cats from fleas, certain ticks, and chewing lice.

It is generally used in cats and kittens 8 weeks of age and older.

Uses of Frontline Plus for Cats

Frontline Plus is mainly used to treat and prevent flea infestations.

It kills adult fleas that are already on the cat and also helps control flea eggs and larvae, which is important for breaking the flea life cycle.

Flea Control

Fleas can cause itching, scratching, skin irritation, and discomfort.

Some cats may also develop flea allergy dermatitis, where even a small number of flea bites can trigger intense itching and skin inflammation.

Frontline Plus helps reduce these problems by killing adult fleas and limiting the development of new fleas.

Breaking the Flea Life Cycle

The ingredient fipronil mainly targets adult fleas and ticks, while (S)-methoprene acts as an insect growth regulator.

(S)-methoprene prevents flea eggs and larvae from developing normally. This helps reduce reinfestation in both the cat and the surrounding environment.

Tick Control

Frontline Plus also helps kill and control certain types of ticks.

Depending on the product label and region, this may include ticks such as the dog tick, lone star tick, brown dog tick, and deer tick.

Ticks can attach to the skin and feed on blood. Some species can also carry infectious organisms, so regular tick control may be important for cats that spend time outdoors.

Chewing Lice

Frontline Plus may also be used to help eliminate chewing lice.

These parasites can cause irritation, itching, and damage to the coat. Treatment helps reduce the number of lice living on the cat.

Who Can Use Frontline Plus for Cats?

Frontline Plus for Cats is generally intended for cats and kittens 8 weeks of age and older.

Follow the specific age and weight requirements printed on your product package, since labeling may vary by country.

Do not use it on younger kittens unless a veterinarian recommends an appropriate alternative.

Usual Dosage

The usual dose is one full applicator applied to one cat.

For the common Frontline Plus for Cats formulation, one applicator contains approximately 0.5 mL of solution.

Use the entire contents of the applicator for one treatment unless your veterinarian or the product label gives different instructions.

How Often to Apply Frontline Plus

Frontline Plus is generally applied once every 30 days for ongoing flea and tick control.

Do not apply it more frequently than directed.

Consistent monthly treatment helps maintain protection and reduces the chance that fleas can complete their life cycle.

How to Apply the Medication

Start by removing one applicator from the package.

Part the cat’s fur at the base of the neck or between the shoulder blades until the skin is clearly visible.

Place the tip of the applicator directly against the skin and squeeze out the entire contents in one spot.

Apply It to the Skin, Not Just the Fur

The medication needs to reach the skin to spread properly.

If it is applied only to the hair, it may not work as effectively.

Parting the fur before application helps make sure the solution reaches the correct area.

Why the Shoulder Blade Area Is Used

Frontline Plus is applied high on the back of the neck because this area is difficult for most cats to reach with their tongue.

This helps reduce the chance of the cat licking and swallowing the medication before it dries.

Let the Application Site Dry

After treatment, allow the application site to dry naturally.

Avoid touching the wet area and prevent children or other pets from contacting it until it has dried.

Do Not Let the Cat Lick the Medication

Try to prevent the cat from licking the treatment area.

If you have more than one pet, keep them from grooming each other until the application sites are completely dry.

Do Not Split One Applicator Between Cats

Use one complete applicator for one cat as directed by the product label.

Do not divide a single applicator between multiple cats unless a veterinarian specifically instructs you to do so.

Do Not Apply Extra Doses

Applying more medication than recommended does not necessarily provide better protection and may increase the risk of side effects.

Use Frontline Plus according to the monthly schedule on the package or as directed by your veterinarian.

What If You Miss a Monthly Dose?

If you forget a scheduled application, apply the next dose when you remember and then continue according to the recommended schedule.

Do not apply two doses at the same time to make up for a missed treatment.

When Fleas May Still Be Seen After Treatment

You may occasionally see fleas after using Frontline Plus, especially if your home already has a significant infestation.

This does not always mean the product has failed. New fleas can continue to emerge from eggs, larvae, and pupae in carpets, bedding, furniture, and other areas of the home.

Regular environmental cleaning may be needed while the infestation is being brought under control.

Managing Fleas in the Home

For a heavy flea infestation, wash pet bedding, vacuum carpets and furniture regularly, and treat other pets in the household with appropriate products.

All animals in the home may need parasite control to prevent fleas from moving between pets.

Indoor Cats May Still Need Protection

Indoor cats can still be exposed to fleas.

Fleas may enter the home on other pets, people, rodents, or visiting animals. Whether year-round prevention is needed depends on your cat’s environment and your veterinarian’s advice.

Outdoor Cats May Have Greater Exposure

Cats that spend time outdoors may be exposed more frequently to fleas and ticks, especially in grassy, wooded, or brush-filled areas.

Monthly protection may be particularly useful for these cats.

Use Only the Cat Formulation

Always use a product specifically labeled Frontline Plus for Cats.

Do not substitute a dog flea and tick product unless a veterinarian confirms that it is appropriate. Products for different species may contain different ingredients or concentrations.

When to Contact a Veterinarian

Contact your veterinarian if your cat develops significant skin irritation, excessive drooling, vomiting, weakness, unusual behavior, or another concerning reaction after treatment.

You should also seek advice if fleas or ticks continue despite correct and consistent use.

Getting the Best Results

For the best protection, apply one full applicator directly to the skin once every 30 days, follow the age and weight requirements on the product label, and avoid skipping treatments.

Consistent monthly use helps kill adult fleas and ticks while also preventing flea eggs and larvae from developing into new adult fleas.

Common Side Effects of Frontline Plus for Cats (Fipronil/methoprene):

  • Excessive Salivation
  • Vomiting or Diarrhea
  • General Itching or Hair Loss

Serious Side Effects of Frontline Plus for Cats (Fipronil/methoprene):

  • Serious Nervous System Reactions
  • Severe or Persistent Vomiting and Diarrhea
  • Severe Skin Reaction

Frontline Plus for Cats (Fipronil/methoprene) is available in the following forms and strength:

Frontline Plus for Cats: Pippettes

  • 100/120 g/L

Fipronil/methoprene: Pippettes

  • (between 8 weeks and older)

Use Only on Cats

Frontline Plus for Cats should only be used on cats and kittens that meet the age and weight requirements on the product label.

Do not use a dog formulation on a cat unless a veterinarian specifically confirms that it is safe. Different flea and tick products may contain different ingredients or concentrations.

Do Not Use on Very Young Kittens

Frontline Plus for Cats is generally intended for kittens 8 weeks of age and older.

For younger kittens, ask your veterinarian about a safer flea-control option.

Avoid Use on Sick or Underweight Cats Without Veterinary Advice

Use extra caution if your cat is ill, weak, underweight, elderly, pregnant, nursing, or taking other medications.

A veterinarian can help determine whether Frontline Plus is appropriate in these situations.

Avoid the Eyes and Mouth

Frontline Plus is for external use only.

Do not allow the product to get into your cat’s eyes or mouth. Apply it to an area where the cat cannot easily lick it.

Prevent Licking After Application

Do not allow your cat to lick the application site before it dries.

If you have multiple pets, prevent them from grooming each other until the treated area is completely dry. Licking the product may cause excessive drooling, vomiting, or other reactions.

Apply Directly to the Skin

Part the fur and apply the medication directly to the skin, not just onto the hair.

Avoid applying it to broken, irritated, or severely inflamed skin unless your veterinarian tells you otherwise.

Do Not Overdose

Use only the amount recommended on the label.

Applying extra medication or treating more frequently than directed does not provide better protection and may increase the risk of side effects.

Do Not Combine Flea and Tick Products Without Advice

Avoid using Frontline Plus together with other flea, tick, insecticide, or pesticide products unless your veterinarian says the combination is safe.

Using multiple parasite treatments at the same time may increase the risk of adverse reactions.

Watch for Skin Reactions

Some cats may develop redness, itching, irritation, scaling, or temporary hair loss at the application site.

Contact your veterinarian if the reaction is severe, spreads, or does not improve.

Watch for Neurological Symptoms

Rare but more serious reactions may include tremors, weakness, poor coordination, unusual behavior, or seizures.

Seek veterinary care promptly if you notice any of these symptoms.

Be Careful Around Children and Other Pets

Do not allow children or other pets to touch the treated area until it is fully dry.

Wash your hands after applying the product, and avoid getting the medication on your skin or in your eyes.

Keep the Product Away From Food

Store Frontline Plus away from food, drinks, pet food, and feeding areas.

Keep the applicators out of reach of children and animals.

Follow the Correct Treatment Schedule

Frontline Plus is generally applied on a monthly schedule, but follow the directions on your specific product package.

Do not shorten the interval between doses unless your veterinarian recommends it.

Contact Your Veterinarian if Problems Occur

Contact your veterinarian if your cat develops persistent vomiting, diarrhea, severe drooling, skin irritation, weakness, tremors, seizures, difficulty breathing, or unusual behavior after treatment.

Using the correct product, dose, and application method helps reduce the risk of problems.

How often should I use Frontline Plus for Cats?

Frontline Plus for Cats is generally applied once every 30 days for ongoing flea and tick protection. Use it according to the schedule on the product label or as directed by your veterinarian.

Can my cat lick Frontline Plus?

Try to prevent your cat from licking the application site until it is completely dry. Licking the medication can cause a bitter taste and may lead to excessive drooling or other temporary reactions. If you have multiple pets, keep them from grooming each other until the treated areas have dried.

Can I bathe my cat after applying Frontline Plus?

Avoid bathing or shampooing your cat immediately after application. Follow the specific bathing instructions on your product label, since frequent bathing or shampooing may affect how long the treatment remains effective.

Can Frontline Plus be used on kittens?

Frontline Plus for Cats is generally intended for kittens 8 weeks of age and older. For younger kittens, ask your veterinarian about an appropriate flea-control option.

Can Frontline Plus be used on indoor cats?

Yes. Indoor cats can still be exposed to fleas through other pets, people, rodents, or animals that enter the home. Your veterinarian can help determine whether regular flea and tick prevention is appropriate for your indoor cat.

Does Frontline Plus kill flea eggs and larvae?

Yes. Frontline Plus contains (S)-methoprene, an insect growth regulator that helps prevent flea eggs and larvae from developing normally. This works together with fipronil, which kills adult fleas, to help break the flea life cycle.

Does Frontline Plus kill ticks?

Yes. Frontline Plus for Cats is used to control certain tick species. The exact tick species covered can vary by regional product labeling, so check your package for the specific claims.

Why am I still seeing fleas after using Frontline Plus?

Seeing fleas after treatment does not always mean the product has failed. Flea eggs, larvae, and pupae may still be present in carpets, bedding, furniture, and other areas of the home. New adult fleas can continue emerging for a while. Regular vacuuming, washing pet bedding, and treating all pets appropriately can help control a household infestation.

Can I use Frontline Plus with another flea treatment?

Do not combine Frontline Plus with another flea, tick, or pesticide treatment unless your veterinarian says it is safe. Using multiple parasite products together may increase the risk of side effects.

What should I do if I miss a monthly treatment?

Apply the next dose when you remember and then continue according to the recommended schedule. Do not apply two doses at once or use extra medication to make up for a missed treatment.

Can Frontline Plus cause side effects?

Yes, although many cats tolerate it well. Possible effects include temporary skin irritation, itching, hair changes at the application site, drooling, vomiting, or diarrhea. More serious neurological reactions are uncommon but require veterinary attention.

What should I do if my cat has a reaction?

Contact your veterinarian if your cat develops persistent vomiting, severe skin irritation, weakness, tremors, seizures, difficulty breathing, or other unusual symptoms. For severe or rapidly worsening symptoms, seek urgent veterinary care.

Can Frontline Plus be used on pregnant or nursing cats?

If your cat is pregnant, nursing, elderly, sick, weak, or taking other medications, ask your veterinarian before using Frontline Plus. Your veterinarian can help determine whether the product is appropriate.

Can I use Frontline Plus for Cats on dogs or other animals?

No. Use Frontline Plus for Cats only on the species listed on the label. Do not use it on other animals unless a veterinarian specifically recommends an appropriate product for that species.

How should I store Frontline Plus?

Keep the applicators in their original packaging and store them according to the label directions. Keep the product away from children, pets, food, and drinks until you are ready to use it.

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Additional Information Book
Generic name:

Fipronil/methoprene, Fipronil S/methoprene

Formulation:

Pipettes, Pippettes

Strength(s):

(between 8 weeks or older), 100/120g/L

Quantities Available:

3

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Frontline Plus for Cats can I order at once from a Canadian pharmacy?

When ordering Frontline Plus for Cats (fipronil/methoprene) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate treatment for pets without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Frontline Plus for Cats is available with a concentration of 100/120g/L and is applied at a dosage of 0.5 ml per application, administered once monthly. For a 90-day supply, this means you would order 3 applicators (3 months x 1 applicator per month).

Do you sell fipronil/methoprene?

Yes, we sell fipronil/methoprene at our website, and you can enjoy competitive prices. However, to purchase fipronil/methoprene, you will need a valid prescription from a veterinarian. We require this to ensure the safe and appropriate dispensing of the medication. You can provide your prescription by mailing, faxing, or uploading it through your online account.

Do you offer shipping of Frontline Plus for Cats (fipronil/methoprene) to the United States?

Yes, we ship Frontline Plus for Cats (fipronil/methoprene) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Frontline Plus for Cats (Fipronil/methoprene). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Frontline Plus for Cats (Fipronil/methoprene).