Indications
Nizoral (active ingredient: ketoconazole) is a prescription medication indicated for the following:
- Fungal Infections: Nizoral is used for the treatment of fungal infections such as tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athlete's foot), and tinea versicolor (a fungal infection that causes lighter or darker patches on the skin).
- Seborrheic Dermatitis: It is also indicated for the treatment of seborrheic dermatitis, a skin condition that causes flaky, itchy, and red skin.
Nizoral belongs to a class of drugs known as imidazole derivatives, which work by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. This action disrupts the fungal cell membrane integrity, leading to fungal cell death and ultimately treating the fungal infection.
Uses and Dosage
Ketoconazole is available in tablet form and should be taken orally once a day, preferably at the same time each day. Read the directions on the prescription label carefully and follow them exactly as directed by your doctor. If you are unsure about any part of the instructions, consult your doctor or pharmacist for clarification. Do not take more or less of the medication or take it more frequently than prescribed by your doctor.
The recommended dosages of ketoconazole for adults can range from 200 to 400 mg per day orally, with the initial dose starting at 200 mg. The dose may be increased as needed, and clinical responsiveness should be monitored. However, note that the specific dosage for an individual should be determined by their doctor based on factors such as their age, weight, and medical history.
Side Effect
Common Side Effects of Nizoral (Ketoconazole):
- Changes in the color or texture of your hair
- Constipation
- Diarrhea
- Dry skin
- Headache
- Heartburn
- Mild itching
- Stomach pain
- Thinning hair
Serious Side Effects of Nizoral (Ketoconazole):
- Difficulty breathing or swallowing
- Hives
- Hoarseness
- Itching
- Rash
- Swelling of the eyes, face, lips, tongue, hands, feet, ankles, or lower legs
- Tiredness or weakness
Form and Strength
Nizoral (Ketoconazole) is available in the following forms and strength:
Ketoconazole: Tablet
- 200mg
Caution
- Drinking alcohol while taking ketoconazole increases the risk of liver damage and uncomfortable symptoms such as flushing, rash, nausea, headache, and swelling of hands and feet. Avoid alcoholic beverages, including wine and beer, as well as medications that contain alcohol such as cough syrup, when taking ketoconazole.
- When undergoing surgery or dental procedures, inform the medical staff that you are taking ketoconazole to ensure proper care.
- Inform your doctor if you are pregnant, plan to become pregnant, or are currently breastfeeding. If you become pregnant while taking ketoconazole, contact your doctor immediately.
- When taking antacids containing aluminum, calcium, or magnesium (such as Maalox, Mylanta, Tums, and others), take them one hour before or two hours after taking ketoconazole.
- Inform your doctor and pharmacist if you are allergic to ketoconazole or any other medications, or any of the ingredients in ketoconazole tablets. Refer to the Medication Guide or ask your pharmacist for a list of ingredients.
Frequently Asked Questions (FAQ)
What is ketoconazole used for?
Ketoconazole is an antifungal medication used to treat various fungal infections.
Can ketoconazole cause hair loss or shedding?
Some people may experience hair loss or shedding when using ketoconazole shampoo, but this is not a common side effect.
How should I take ketoconazole tablets?
Take ketoconazole tablets exactly as prescribed by your doctor. Follow the dosage instructions provided, and do not take more or less of the medication than recommended.
Can I use ketoconazole if I am allergic to other antifungal medications?
If you are allergic to other antifungal medications, it is important to inform your doctor before taking ketoconazole, as you may still be at risk of an allergic reaction.
What should I do if I miss a dose of ketoconazole?
If you miss a dose of ketoconazole, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
Resources
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018533s040lbl.pdf
- https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-limits-usage-nizoral-ketoconazole-oral-tablets-due-potentially
- https://nizoral.com/
- https://www.mayoclinic.org/drugs-supplements/ketoconazole-topical-route/description/drg-20067739
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