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Grisovin (generically known as Griseofulvin) is an antifungal medication used to treat fungal infections of the skin, nails, scalp, and hair. It is usually used when other medications have failed to treat the infection.
Griseofulvin, the active ingredient in Grisovin, works by interfering with fungal mitosis, preventing fungal cells from dividing and multiplying. This causes the fungus to stop growing and spreading, allowing the body's immune system to clear the infection.
Grisovin also binds to keratin in precursor cells and makes them resistant to fungal infections. The medication only works against fungal infections and does not treat infections due to bacteria or yeast.
Use and Dosage
Grisovin is a tablet that should be taken orally as directed by your doctor. To ensure optimal absorption, take it with or after a meal that contains a moderate amount of fat. If you are following a low-fat diet, be sure to speak with your doctor or pharmacist about specific dietary instructions.
Although your symptoms may get better in a few days, you will have to take griseofulvin for a long time before the infection is completely gone. The length of treatment will depend on the type of infection you have and can range from several weeks to months. Nail infections may require several months to a year or longer to treat.
It is usually taken for 2 to 4 weeks for skin infections, 4 to 6 weeks for hair and scalp infections, 4 to 8 weeks for foot infections, 3 to 4 months for fingernail infections, and at least 6 months for toenail infections. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any part you do not understand. Take griseofulvin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
For antifungal medication to be most effective, maintain a constant level of medication in your body. To achieve this, take Grisovin at evenly spaced intervals. Also, continue taking the medication for the full length of the prescribed treatment even if you start to feel better after a few days. Stopping the medication too early could result in a relapse of the infection as the fungus may continue to grow.
Common Side Effects of Grisovin (Griseofulvin):
- Diarrhea or loose stools
- Upset stomach
Serious Side Effects of Grisovin (Griseofulvin):
- Abdominal or stomach pain
- Black, tarry stools
- Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- Chest pain
- Clay-colored stools
- Cloudy urine
- Dark urine
- Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- Loss of appetite
- Mouth soreness or irritation
- Numbness, tingling, pain, or weakness in the hands or feet
- Painful or difficult urination
- Shortness of breath
- Skin rash
- Sore throat
- Swollen glands
- Unpleasant breath odor
- Unusual bleeding or bruising
- Vomiting of blood
- Yellow eyes or skin
Forms and Strength
Grisovin (Griseofulvin) is available in the following forms and strength:
- 250 mg
- The possibility of drug interactions with other medications, both prescription and over the counter, as well as herbal supplements.
- The need to monitor liver function during treatment, as Griseofulvin may cause liver damage in rare cases.
- The possibility of cross-reactivity with penicillin, although this is not common.
- The need to follow your veterinarian's directions and caution very carefully when using Griseofulvin in animals.
- Griseofulvin may cause photosensitivity (sensitivity to sunlight), avoid excessive sun exposure, or use protective clothing and sunscreen.
- Patients with porphyria (a metabolic disorder) should avoid using Griseofulvin, as it can exacerbate the condition.
- Griseofulvin should not be taken during pregnancy, as it may harm the developing fetus.
- Breastfeeding mothers should consult with their healthcare provider before taking Griseofulvin, as it may be passed into breast milk and harm the nursing infant.
- Individuals with liver disease or a history of liver problems should be cautious when taking Griseofulvin, as it may exacerbate the condition.
- Griseofulvin may interfere with certain laboratory tests, so it is recommended to inform the laboratory personnel about the medication before undergoing any tests.
Frequently Asked Questions (FAQ)
How long does it take for Grisovin to work?
The length of treatment with Grisovin can vary depending on the severity of the infection. It may take several weeks or months for symptoms to improve, continue taking the medication as directed even if symptoms have improved.
Can Grisovin be used to treat vaginal yeast infections?
No, Grisovin is not effective in treating vaginal yeast infections. It is only used for fungal infections of the skin, scalp, hair, or nails.
Can Grisovin be used in children?
Yes, Grisovin can be used in children under the supervision of a doctor. The dosage may need to be adjusted depending on the child's weight and age.
Can Grisovin be used for toenail fungus?
Yes, Grisovin can be used to treat toenail fungus, but it may take several months for the infection to clear. Other medications, such as terbinafine or itraconazole, may offer faster results.
How is Grisovin different from other antifungal medications?
Grisovin is an older medication that works by binding to the protein keratin in the skin, nails, and hair, where it is slowly released to treat the infection. Other antifungal medications, such as terbinafine and fluconazole, work by directly targeting the fungal cell.
It's important to purchase Grisovin from verified Canadian pharmacy.