Before taking Nexletol, tell your healthcare provider about your complete medical history, including any allergies, medical conditions, and medications you take.
Allergic Reactions
Do not take Nexletol if you are allergic to bempedoic acid or any of the ingredients in the medication.
Seek immediate medical attention if you develop signs of a serious allergic reaction, such as:
- Rash or hives
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing
Tendon Problems
Nexletol may increase the risk of tendon injury, including tendon rupture.
The risk may be higher in people who:
- Are over 60 years of age
- Have a history of tendon disorders
- Use certain medications that can affect tendons
Contact your healthcare provider immediately if you experience:
- Sudden tendon pain
- Swelling
- Bruising
- Difficulty moving a joint
Liver and Kidney Problems
If you have liver disease or kidney disease, your healthcare provider may monitor you more closely during treatment.
Regular blood tests may be recommended to help assess liver and kidney function while taking Nexletol.
Gout and High Uric Acid Levels
Nexletol may increase uric acid levels and can trigger gout flare-ups in some people.
Tell your healthcare provider if you have a history of gout or develop symptoms such as:
- Sudden joint pain
- Joint swelling
- Redness or warmth around a joint
Pregnancy and Breastfeeding
If you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed, talk to your healthcare provider before taking Nexletol.
The safety of Nexletol during pregnancy and breastfeeding has not been fully established. Your healthcare provider will determine whether the potential benefits of treatment outweigh any potential risks.
Drug Interactions
Nexletol may interact with other medications, vitamins, herbal products, and supplements.
Before starting treatment, tell your healthcare provider about everything you take, including:
- Prescription medications
- Over-the-counter products
- Vitamins
- Herbal supplements
This helps reduce the risk of potential drug interactions.
Muscle Pain
Some people may experience muscle pain, tenderness, or weakness while taking Nexletol.
Although uncommon, muscle symptoms may occasionally be a sign of a serious condition called rhabdomyolysis, which involves muscle breakdown and can lead to kidney problems.
Contact your healthcare provider if you develop unexplained muscle pain, weakness, or severe muscle symptoms.
Dizziness and Blurred Vision
Nexletol may cause dizziness or blurred vision in some people.
Until you know how the medication affects you, avoid driving, operating machinery, or performing activities that require alertness and clear vision.
Surgery and Medical Procedures
If you are scheduled for surgery or a medical procedure, tell your healthcare provider that you are taking Nexletol.
Your healthcare team can determine whether any special precautions are needed before, during, or after the procedure.
Regular follow-up appointments and cholesterol monitoring can help ensure Nexletol remains safe and effective throughout your treatment.
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