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Invokana is a prescription medication used to treat type 2 diabetes. It contains the active substance canagliflozin. Canagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor indicated: It works by helping the kidneys remove sugar from the blood, ultimately lowering blood sugar levels.

Canagliflozin is used together with diet and exercise to treat adults with type 2 diabetes. It is not for people with type 1 diabetes and is not used to lower blood sugar levels in those without diabetes. Invokana is effective to lower the risk of end-stage kidney disease, cardiovascular events, and worsening of kidney function in people with type 2 diabetes.

Uses and Dosage

Invokana comes in the form of a tablet to take by mouth as directed by your doctor, usually once daily before the first meal of the day. The dosage of Invokana is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

The recommended starting dosage for Invokana is 100mg, taken orally once daily before the first meal of the day. This dosage can be adjusted based on factors such as the patient's medical condition, response to treatment, and other medications they may be taking. However, the maximum recommended dosage for Invokana is 300mg per day for additional glycemic control. Patients should only take the dosage prescribed by their doctor and inform them of all the products they are using.

Side Effects

Common Side Effects of Invokana (Canagliflozin):

  • Constipation
  • Dizziness
  • Dry mouth
  • Fatigue
  • Frequent urination
  • Lightheadedness
  • Nausea
  • Thirst

Serious Side Effects of Invokana (Canagliflozin)

  • Signs of a bladder infection (fever, burning or pain when urinating, urgent urination)
  • Signs of kidney problems (change in urine output, swelling of lower extremities)
  • Signs of hyperkalemia or elevated levels of potassium in the blood (muscle weakness, irregular heartbeat)
  • Hypoglycemia (sudden sweating, tremors, hunger, blurred vision, tingling of hands or feet)
  • Hyperglycemia (thirst, increased urination, confusion, drowsiness, fruity breath odor)

Form and Strength

Invokana (Canagliflozin) is available in the following forms and strengths:

Invokana: Tablet

  • 100 mg
  • 300 mg


  • If you display signs and symptoms of metabolic acidosis, ketoacidosis should be assessed regardless of their blood glucose level. If ketoacidosis is suspected, INVOKANA treatment should be discontinued, and the patient should be promptly evaluated and treated.
  • Consider temporarily discontinuing of INVOKANA in settings of reduced oral intake or fluid losses. If acute kidney injury occurs, discontinue and promptly treat. Monitor renal function during therapy.
  • Before taking canagliflozin (INVOKANA), inform one's doctor or pharmacist if they are allergic to it, or if they have any other allergies, as the medication may contain inactive ingredients which can cause allergic reactions or other problems.
  • During pregnancy, canagliflozin should be used only when clearly needed and after discussing the risks and benefits with a healthcare professional.
  • There have been reports of serious, life-threatening genital infections associated with the use of the medication, including cases of pain, tenderness, erythema, or swelling in the genital or perineal area, along with fever or malaise.
  • If hypersensitivity reactions occur, the use of INVOKANA should be discontinued, and the patient should be treated according to the standard of care, and monitored until signs and symptoms resolve.
  • Drinking alcohol while taking INVOKANA can increase the risk of hypoglycemia (low blood sugar) and dehydration, so it is important to limit alcohol consumption while taking the medication.
  • INVOKANA is not recommended for use during pregnancy, and women who are pregnant or planning to become pregnant should discuss alternative treatment options with their doctor.

Frequently Asked Questions (FAQ)

Can Invokana be taken with other diabetes medications?

Yes, INVOKANA can be taken with other diabetes medications, but you should consult a doctor before taking any new medications to avoid potential drug interactions.

Can Invokana cause dehydration?

Yes, INVOKANA can cause dehydration, and it is important to drink enough fluids while taking the medication.

Can Canagliflozin cause low blood pressure?

Yes, Canagliflozin can cause low blood pressure, and patients should be cautious when rising from a sitting or lying position to avoid dizziness or fainting.

How long does it take for Canagliflozin to start working?

Canagliflozin can lower blood sugar levels within a few days of starting the medication, but it may take up to 2-3 months to see the full effect.

Can INVOKANA help people lose weight?

It is possible that some people may experience weight loss while taking INVOKANA, but it is not a primary goal of the medication.


Additional information

Generic name:



Film Coated Tablet, Tablet


100mg, 300mg

Quantities Available:

30, 60, 90


Additional Information Book

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Invokana (Canagliflozin). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Invokana (Canagliflozin).