Indications
Hepsera is a prescription antiviral medication used to treat chronic hepatitis B in adults and children over 12 years of age. It contains an active ingredient called Adefovir dipivoxil. Adefovir is in a class of medications called nucleotide analogs. It works by blocking an enzyme that is necessary for the hepatitis B virus to replicate, thereby slowing the growth and spread of the virus in the body. By reducing viral replication, Hepsera can help to reduce inflammation and damage to the liver caused by the virus.
Hepsera is not a cure for hepatitis B, but it can help to manage the condition and prevent complications. It cannot prevent the spread of hepatitis B to other people.
Use and Dosage
Adefovir is available in tablet form and should be taken orally with or without food as prescribed by your doctor, generally once a day. The appropriate dosage will depend on your medical condition and response to treatment and take Adefovir regularly to obtain the maximum benefits.
Do not use Adefovir as the sole treatment for patients infected with both hepatitis B and HIV. Before and during treatment, an HIV test is recommended to ensure you receive appropriate care. Please speak with your doctor or pharmacist for further information.
To help you remember, take it at the same time each day. Do not increase or decrease the dosage or discontinue the medication without the guidance of your doctor or pharmacist. Make sure you refill your prescription before it runs out.
While taking Adefovir, there is a possibility of certain issues, such as worsening of your condition, decreased response to treatment, or being infected with the virus again with resistant strains. If new symptoms arise during or after treatment, immediately inform your doctor.
Side Effects
Common Side Effects of Hepsera (Adefovir):
- Diarrhea
- Gas
- Headache
- Indigestion
- Rash
- Runny nose
- Sore throat
- Weakness
Serious Side Effects of Hepsera (Adefovir):
- Blood in the urine
- Change in frequency of urination or amount of urine
- Dark urine
- Diarrhea
- Difficult breathing
- Drowsiness
- Gas
- General tiredness and weakness
- Increased thirst
- Light-colored stools
- Loss of appetite
- Nausea and vomiting
- Swelling of the feet or lower legs
- Upper right abdomen or stomach pain
- Upset stomach
- Yellow eyes and skin
Forms and Strength
Hepsera (Adefovir) is available in the following forms and strength:
Hepsera: Tablet
- 10 mg
Adefovir: Tablet
- 10 mg
Cautions
- Hepsera may cause liver problems, including worsening of hepatitis B after you stop taking it.
- Hepsera can also cause kidney problems, including kidney failure and Fanconi syndrome.
- Hepsera may lead to lactic acidosis, which is a build-up of lactic acid in the body and can be fatal in some cases.
- Hepsera may cause a decrease in bone mineral density, which can increase the risk of fractures.
- People who are allergic to adefovir dipivoxil or any of the ingredients in Hepsera should not take this medication.
- Hepsera may cause a decrease in phosphate levels, which can cause muscle weakness, bone pain, and other symptoms.
- Hepsera may interact with other medications, tell your doctor about all the medications, and supplements you are taking before starting treatment with Hepsera.
- Pregnant women should talk to their doctor about the risks and benefits of taking this medication.
- Hepsera is not recommended for use in children under 12 years of age.
Frequently Asked Questions (FAQ)
How long do I have to take Adefovir (Hepsera)?
You should continue to take Adefovir (Hepsera) for as long as your provider instructs you to. It isn't known what the ideal amount of time you should take the medication for your HBV infection is. But many people have taken Adefovir (Hepsera) for several years without serious problems.
Can Hepsera (Adefovir) be used during pregnancy?
Pregnant women should talk to their doctor about the potential risks and benefits of taking Hepsera during pregnancy. Hepsera should only be used during pregnancy if the potential benefits outweigh the potential risks.
Are there any interactions between Hepsera (Adefovir) and other medications or supplements?
Hepsera may interact with other medications or supplements, tell your doctor about all the medications, and supplements you are taking before starting treatment with Hepsera.
Can children take Hepsera (Adefovir)?
Hepsera is not recommended for use in children under 12 years of age.
Resources
- https://www.everydayhealth.com/drugs/adefovir
- https://medlineplus.gov/druginfo/meds/a605024.html
- https://www.drugs.com/mtm/hepsera.html
- https://www.goodrx.com/adefovir/what-is
- https://www.webmd.com/drugs/2/drug-64166/hepsera-oral/details
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021449s020lbl.pdf
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