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Prescription Required
Formulation: Tablet
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Glyxambi contains two active ingredients: empagliflozin and linagliptin. It is a prescription medication used to help manage type 2 diabetes mellitus in adults.
It is usually prescribed along with a healthy diet, regular exercise, and other parts of a diabetes treatment plan.
Type 2 diabetes develops when the body does not use insulin effectively or does not make enough insulin to keep blood sugar within a healthy range.
Glyxambi helps lower blood sugar in two different ways because each active ingredient works through a separate mechanism.
Empagliflozin belongs to a group of medicines called sodium-glucose co-transporter 2 (SGLT2) inhibitors.
The kidneys normally filter glucose from the blood and then reabsorb much of it back into the bloodstream.
Empagliflozin blocks part of this reabsorption process.
When empagliflozin blocks SGLT2 proteins in the kidneys, more glucose stays in the urine instead of returning to the blood.
The extra glucose is then removed from the body through urination.
This helps lower the amount of glucose circulating in the bloodstream.
Linagliptin belongs to a group of medicines called DPP-4 inhibitors.
It works by increasing the activity of natural hormones called incretins.
These hormones are released after you eat and help the body manage blood sugar.
Incretin hormones help the pancreas release more insulin when blood sugar is high.
They also help reduce the amount of glucose released by the liver.
By preventing the breakdown of these hormones, linagliptin allows their effects to last longer.
Empagliflozin and linagliptin work in different parts of the body.
Empagliflozin helps the kidneys remove excess glucose, while linagliptin helps improve the body’s insulin response and reduce glucose production by the liver.
Using both mechanisms together may provide better blood sugar control than either approach alone in some patients.
Glyxambi can help lower fasting blood sugar, which is the glucose level measured after you have not eaten for several hours.
This is one important measure of diabetes control.
Linagliptin helps the body respond more effectively when blood sugar rises after eating.
This can help reduce large increases in post-meal blood sugar.
With regular use, Glyxambi can help lower A1C levels.
A1C reflects your average blood sugar over approximately the previous two to three months and is often used to measure long-term diabetes control.
The empagliflozin component has also been associated with important cardiovascular benefits in certain adults with type 2 diabetes and established cardiovascular disease.
Your healthcare provider may consider your heart health when deciding whether Glyxambi is appropriate for your treatment plan.
Glyxambi does not contain insulin.
Instead, it helps your body lower blood sugar by increasing glucose removal through the urine and improving the body’s natural hormonal response to glucose.
Glyxambi helps control blood sugar, but it does not cure diabetes.
Treatment may need to continue long term along with healthy eating, regular physical activity, and blood sugar monitoring.
Glyxambi works best when combined with a suitable diet and exercise program.
Medication can help control blood sugar, but it does not replace lifestyle measures recommended by your healthcare provider.
Your healthcare provider may monitor your blood sugar, A1C, kidney function, blood pressure, and overall response to treatment.
These checks help determine whether Glyxambi is working well and whether your treatment needs to be adjusted.
Glyxambi may be prescribed when blood sugar remains above target and your healthcare provider believes that combining an SGLT2 inhibitor and a DPP-4 inhibitor may provide additional benefit.
The decision depends on your blood sugar control, kidney function, cardiovascular history, and other medications.
Type 2 diabetes can change over time, so your treatment plan may also need to change.
Your healthcare provider may adjust your medication, add another treatment, or recommend different goals depending on your blood sugar results and overall health.
Take Glyxambi exactly as prescribed and continue following your recommended diet, exercise, blood sugar monitoring, and medical follow-up plan.
Consistent treatment can help improve long-term blood sugar control and reduce the risk of complications related to poorly controlled diabetes.
Glyxambi is taken by mouth once daily, usually in the morning.
It can be taken with or without food, so you can choose the option that is easiest to follow consistently unless your healthcare provider gives you different instructions.
Take the tablet with a glass of water.
Swallow it whole and avoid crushing, chewing, or splitting it unless your healthcare provider or pharmacist specifically tells you that your tablet can be divided.
A common starting dose is 10 mg empagliflozin/5 mg linagliptin once daily.
Your healthcare provider may choose this dose based on your blood sugar levels, kidney function, other medications, and overall treatment needs.
If additional blood sugar control is needed and the medication is well tolerated, the dose may be increased to 25 mg empagliflozin/5 mg linagliptin once daily.
Do not increase the dose on your own.
Try to take Glyxambi at about the same time every morning.
A regular schedule can help you remember your medication and provide more consistent blood sugar control.
Your dose is individualized according to factors such as your A1C, blood sugar readings, kidney function, other medical conditions, and response to treatment.
Always follow the dosing instructions provided by your healthcare provider.
Taking more Glyxambi than prescribed will not necessarily improve blood sugar control and may increase the risk of side effects.
Do not take additional tablets unless your healthcare provider specifically tells you to.
Do not stop taking Glyxambi without talking to your healthcare provider.
Stopping treatment may cause your blood sugar to rise and make your diabetes more difficult to control.
The empagliflozin component causes more glucose and fluid to leave the body through the urine.
Drink enough fluids unless your healthcare provider has told you to limit your fluid intake, especially during hot weather, exercise, or illness.
Check your blood sugar as directed by your healthcare provider.
Your provider may also monitor your A1C, kidney function, and blood pressure to make sure Glyxambi is working safely and effectively.
Take Glyxambi once daily in the morning, use it consistently, follow your prescribed dose, and continue your recommended diet and exercise plan.
Contact your healthcare provider if your blood sugar remains too high or too low, or if you develop concerning side effects.
Glyxambi (Empagliflozin/Linagliptin) is available in the following forms and strength:
Glyxambi should not be used in people who are on dialysis.
Tell your healthcare provider if you have kidney disease before starting treatment. Kidney function may affect whether Glyxambi is appropriate for you and how closely you need to be monitored.
Do not take Glyxambi if you are allergic to empagliflozin, linagliptin, or any other ingredient in the medication.
Seek immediate medical attention if you develop swelling of the face, lips, tongue, or throat, severe rash, or difficulty breathing.
The empagliflozin component can increase the risk of diabetic ketoacidosis, a serious condition caused by a buildup of acids called ketones in the blood.
This can sometimes occur even when blood sugar is not extremely high.
Seek urgent medical attention if you develop nausea, vomiting, abdominal pain, unusual tiredness, difficulty breathing, or fruity-smelling breath.
Linagliptin has been associated with rare cases of pancreatitis, or inflammation of the pancreas.
Tell your healthcare provider if you have a history of pancreatitis. Seek medical attention if you develop severe, persistent abdominal pain, especially if it spreads to your back or is accompanied by vomiting.
Glyxambi may increase the risk of urinary tract infections (UTIs) because empagliflozin causes more glucose to leave the body through the urine.
Symptoms may include burning during urination, frequent urination, pelvic discomfort, fever, or blood in the urine.
Contact your healthcare provider if these symptoms occur.
Empagliflozin can also increase the risk of genital fungal or yeast infections.
Symptoms may include itching, redness, irritation, unusual discharge, or discomfort in the genital area.
Tell your healthcare provider if you have frequent or recurring infections.
Glyxambi can cause the body to lose more fluid through urination.
This may lead to dehydration, dizziness, or low blood pressure, especially in older adults, people with kidney problems, or those taking diuretics.
Drink enough fluids unless your healthcare provider has told you to restrict your fluid intake.
Diuretics, sometimes called water pills, can increase fluid loss.
Taking them with Glyxambi may increase the risk of dehydration, dizziness, or low blood pressure. Your healthcare provider may monitor your blood pressure and kidney function more closely.
Glyxambi does not usually cause significant hypoglycemia when used by itself.
However, the risk of low blood sugar increases when it is taken with insulin or certain other diabetes medicines.
Symptoms may include shakiness, sweating, dizziness, hunger, confusion, weakness, or headache.
Contact your healthcare provider promptly if you develop persistent vomiting, severe abdominal pain, signs of dehydration, frequent infections, or unusual changes in blood sugar.
Seek urgent medical attention for symptoms of ketoacidosis, a severe allergic reaction, or another rapidly worsening condition.
While taking Glyxambi, your healthcare provider may monitor your blood sugar, A1C, kidney function, blood pressure, and overall response to treatment.
Regular follow-up helps make sure the medication continues to work safely and effectively.
Glyxambi is usually taken once daily, with or without food, as directed by your healthcare provider. Swallow the tablet whole with a glass of water. Do not crush, chew, or split the tablet unless your healthcare provider or pharmacist specifically tells you that it is safe to do so.
No. Glyxambi is approved for type 2 diabetes, not type 1 diabetes. People with type 1 diabetes require insulin, and Glyxambi is not a substitute for insulin treatment.
Some people may lose a small amount of weight while taking Glyxambi, mainly because the empagliflozin component causes extra glucose to leave the body through the urine. Any weight loss can vary from person to person and should not be considered a guaranteed effect of the medication.
Yes, Glyxambi may be used with certain other diabetes medications. However, combining it with insulin or medicines that increase insulin release may raise the risk of low blood sugar. Your healthcare provider may need to adjust your treatment and monitor your blood sugar more closely. Always tell your healthcare provider about all diabetes medicines, supplements, and other medications you use before starting Glyxambi.
| Generic name: | Empagliflozin/Linagliptin |
|---|---|
| Formulation: | Tablet |
| Strength(s): | 10/5mg, 25/5mg |
| Quantities Available: | 30, 90 |
Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.
Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.
When ordering Glyxambi (empagliflozin/linagliptin) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.
Here’s what you need to know:
Dosage and Quantity: Glyxambi is commonly prescribed in 10/5mg or 25/5mg tablets, taken once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).
No, we do not sell empagliflozin/linagliptin directly on our website. However, you can still enjoy competitive prices on Glyxambi, which contains empagliflozin and linagliptin as an active ingredient. To purchase Glyxambi from us, you will need a valid prescription from your healthcare provider. We require this to dispense the medication safely. You can conveniently submit your prescription by mail, fax, or upload it through your online account.
Yes, we ship Glyxambi (empagliflozin/linagliptin) to both the United States and Puerto Rico.
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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Glyxambi (Empagliflozin/Linagliptin). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Glyxambi (Empagliflozin/Linagliptin).
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